A Review of the Inhibition of the Mitochondrial ATP Synthase by IF1 in vivo: Reprogramming Energy Metabolism and Inducing Mitohormesis

Mitochondrial cAMP-PKA signaling: What do we really know?

(2018) Yasmine Ould Amer et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

The role of the ATPase inhibitor factor 1 (IF 1 ) in cancer cells adaptation to hypoxia and anoxia

(2018) G. Sgarbi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

LZ205, a newly synthesized flavonoid compound, exerts anti-inflammatory effect by inhibiting M1 macrophage polarization through regulating PI3K/AKT/mTOR signaling pathway

(2018) Dongsheng Bai et al.   EXPERIMENTAL CELL RESEARCH

Assembly of the membrane domain of ATP synthase in human mitochondria

(2018) Jiuya He et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-resolution cryo-EM analysis of the yeast ATP synthase in a lipid membrane

(2018) Anurag P. Srivastava et al.   SCIENCE

Structure, mechanism, and regulation of the chloroplast ATP synthase

(2018) Alexander Hahn et al.   SCIENCE

Reactive Oxygen Species Deficiency Due to Ncf1-Mutation Leads to Development of Adenocarcinoma and Metabolomic and Lipidomic Remodeling in a New Mouse Model of Dextran Sulfate Sodium-Induced Colitis

(2018) Lina Carvalho et al.   Frontiers in Immunology

The Role of Mitochondrial H+-ATP Synthase in Cancer

(2018) Pau B. Esparza-Moltó et al.   Frontiers in Oncology

Loss of hepatic LRPPRC alters mitochondrial bioenergetics, regulation of permeability transition and trans-membrane ROS diffusion

(2017) Alexanne Cuillerier et al.   HUMAN MOLECULAR GENETICS

Control of Mitochondrial Remodeling by the ATPase Inhibitory Factor 1 Unveils a Pro-survival Relay via OPA1

(2017) Danilo Faccenda et al.   Cell Reports

Mitochondrial ROS Production Protects the Intestine from Inflammation through Functional M2 Macrophage Polarization

(2017) Laura Formentini et al.   Cell Reports

PDE2A2 regulates mitochondria morphology and apoptotic cell death via local modulation of cAMP/PKA signalling

(2017) Stefania Monterisi et al.   eLife

The ATPase Inhibitory Factor 1 (IF1): A master regulator of energy metabolism and of cell survival

(2016) Javier García-Bermúdez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Mitonuclear communication in homeostasis and stress

(2016) Pedro M. Quirós et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Regulation of mitochondrial functions by protein phosphorylation and dephosphorylation

(2016) Sangbin Lim et al.   Cell and Bioscience

Mitochondrial ROS Signaling in Organismal Homeostasis

(2015) Gerald S. Shadel et al.   CELL

The Opa1-Dependent Mitochondrial Cristae Remodeling Pathway Controls Atrophic, Apoptotic, and Ischemic Tissue Damage

(2015) Tatiana Varanita et al.   Cell Metabolism

Evolution of Mitochondria as Signaling Organelles

(2015) Navdeep S. Chandel   Cell Metabolism

The Mitochondrial Permeability Transition Pore: Channel Formation by F-ATP Synthase, Integration in Signal Transduction, and Role in Pathophysiology

(2015) Paolo Bernardi et al.   PHYSIOLOGICAL REVIEWS

Down-regulation of oxidative phosphorylation in the liver by expression of the ATPase inhibitory factor 1 induces a tumor-promoter metabolic state

(2015) Fulvio Santacatterina et al.   Oncotarget

Acetaminophen cytotoxicity is ameliorated in a human liver organotypic co-culture model

(2015) Leonard J. Nelson et al.   Scientific Reports

PKA Phosphorylates the ATPase Inhibitory Factor 1 and Inactivates Its Capacity to Bind and Inhibit the Mitochondrial H+-ATP Synthase

(2015) Javier García-Bermúdez et al.   Cell Reports

The H+-ATP synthase: A gate to ROS-mediated cell death or cell survival

(2014) Inmaculada Martínez-Reyes et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Mitohormesis

(2014) Jeanho Yun et al.   Cell Metabolism

In vivo inhibition of the mitochondrial H+-ATP synthase in neurons promotes metabolic preconditioning

(2014) L. Formentini et al.   EMBO JOURNAL

Loss of LRPPRC causes ATP synthase deficiency

(2014) A. Mourier et al.   HUMAN MOLECULAR GENETICS

Unraveling the Truth About Antioxidants: Mitohormesis explains ROS-induced health benefits

(2014) Michael Ristow   NATURE MEDICINE

Advances in targeting cyclic nucleotide phosphodiesterases

(2014) Donald H. Maurice et al.   NATURE REVIEWS DRUG DISCOVERY

cAMP signaling in subcellular compartments

(2014) Konstantinos Lefkimmiatis et al.   PHARMACOLOGY & THERAPEUTICS

Pathway of binding of the intrinsically disordered mitochondrial inhibitor protein to F1-ATPase

(2014) J. V. Bason et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An uncoupling channel within the c-subunit ring of the F1FO ATP synthase is the mitochondrial permeability transition pore

(2014) K. N. Alavian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The ATP synthase: the understood, the uncertain and the unknown

(2013) John E. Walker   BIOCHEMICAL SOCIETY TRANSACTIONS

Mitochondrial Cristae Shape Determines Respiratory Chain Supercomplexes Assembly and Respiratory Efficiency

(2013) Sara Cogliati et al.   CELL

Role of the c subunit of the FOATP synthase in mitochondrial permeability transition

(2013) Massimo Bonora et al.   CELL CYCLE

IF1 limits the apoptotic-signalling cascade by preventing mitochondrial remodelling

(2013) D Faccenda et al.   CELL DEATH AND DIFFERENTIATION

Mitochondrial Ca2+ Uptake Induces Cyclic AMP Generation in the Matrix and Modulates Organelle ATP Levels

(2013) Giulietta Di Benedetto et al.   Cell Metabolism

Degradation of IF1 controls energy metabolism during osteogenic differentiation of stem cells

(2013) María Sánchez-Aragó et al.   EMBO REPORTS

Ca2+and cAMP cross-talk in mitochondria

(2013) Giulietta Di Benedetto et al.   JOURNAL OF PHYSIOLOGY-LONDON

Dimers of mitochondrial ATP synthase form the permeability transition pore

(2013) V. Giorgio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression, regulation and clinical relevance of the ATPase inhibitory factor 1 in human cancers

(2013) M Sánchez-Aragó et al.   Oncogenesis

Mitochondria-Mediated Energy Adaption in Cancer: The H+-ATP Synthase-Geared Switch of Metabolism in Human Tumors

(2012) María Sánchez-Aragó et al.   ANTIOXIDANTS & REDOX SIGNALING

Role of Mitochondrial Ca2+ in the Regulation of Cellular Energetics

(2012) Brian Glancy et al.   BIOCHEMISTRY

The Mitochondrial ATPase Inhibitory Factor 1 Triggers a ROS-Mediated Retrograde Prosurvival and Proliferative Response

(2012) Laura Formentini et al.   MOLECULAR CELL

Mitochondria as sensors and regulators of calcium signalling

(2012) Rosario Rizzuto et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Kynurenines in the mammalian brain: when physiology meets pathology

(2012) Robert Schwarcz et al.   NATURE REVIEWS NEUROSCIENCE

Protein Phosphorylation and Prevention of Cytochrome Oxidase Inhibition by ATP: Coupled Mechanisms of Energy Metabolism Regulation

(2011) Rebeca Acin-Perez et al.   Cell Metabolism

Mitochondrial and Nuclear Genomic Responses to Loss ofLRPPRCExpression

(2010) Vishal M. Gohil et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Up-regulation of the ATPase Inhibitory Factor 1 (IF1) of the Mitochondrial H+-ATP Synthase in Human Tumors Mediates the Metabolic Shift of Cancer Cells to a Warburg Phenotype

(2010) Laura Sánchez-Cenizo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

LRPPRC and SLIRP Interact in a Ribonucleoprotein Complex That Regulates Posttranscriptional Gene Expression in Mitochondria

(2010) Florin Sasarman et al.   MOLECULAR BIOLOGY OF THE CELL

Cyclic AMP Produced inside Mitochondria Regulates Oxidative Phosphorylation

(2009) Rebeca Acin-Perez et al.   Cell Metabolism

IEX-1 targets mitochondrial F1Fo-ATPase inhibitor for degradation

(2008) L Shen et al.   CELL DEATH AND DIFFERENTIATION

Regulation of Mitochondrial Structure and Function by the F1Fo-ATPase Inhibitor Protein, IF1

(2008) Michelangelo Campanella et al.   Cell Metabolism

cAMP-dependent protein kinase regulates the mitochondrial import of the nuclear encoded NDUFS4 subunit of complex I

(2008) Domenico De Rasmo et al.   CELLULAR SIGNALLING