Combined Use of Emodin and Ginsenoside Rb1 Exerts Synergistic Neuroprotection in Cerebral Ischemia/Reperfusion Rats

Panax notoginsenoside saponins Rb1 regulates the expressions of Akt/ mTOR/PTEN signals in the hippocampus after focal cerebral ischemia in rats

(2018) Yi-Tian Yan et al.   BEHAVIOURAL BRAIN RESEARCH

Multiple and complex influences of connexins and pannexins on cell death

(2018) Jérôme Gilleron et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Thrombolytic therapies for ischemic stroke: Triumphs and future challenges

(2018) Aimen Moussaddy et al.   NEUROPHARMACOLOGY

2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association

(2018) William J. Powers et al.   STROKE

Effects of Panax notoginseng ginsenoside Rb1 on abnormal hippocampal microenvironment in rats

(2017) Shiyun Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Effects and mechanisms of compound Chinese medicine and major ingredients on microcirculatory dysfunction and organ injury induced by ischemia/reperfusion

(2017) Jing-Yan Han et al.   PHARMACOLOGY & THERAPEUTICS

Reduction of Ischemic Brain Edema by Combined use of Paeoniflorin and Astragaloside IV via Down-Regulating Connexin 43

(2017) Heling Chu et al.   PHYTOTHERAPY RESEARCH

Emodin from Polygonum multiflorum ameliorates oxidative toxicity in HT22 cells and deficits in photothrombotic ischemia

(2016) Sung Min Ahn et al.   JOURNAL OF ETHNOPHARMACOLOGY

Antidepressants Impact Connexin 43 Channel Functions in Astrocytes

(2016) Tiffany Jeanson et al.   Frontiers in Cellular Neuroscience

Translational Stroke Research on Blood-Brain Barrier Damage: Challenges, Perspectives, and Goals

(2016) Yejie Shi et al.   Translational Stroke Research

Heart Disease and Stroke Statistics—2016 Update

(2015) Dariush Mozaffarian et al.   CIRCULATION

Active Compounds of Rhubarb Root and Rhizome in Animal Model Experiments of Focal Cerebral Ischemia

(2015) Ai-ju Liu et al.   Evidence-based Complementary and Alternative Medicine

Neuroprotection of Sanhua Decoction against Focal Cerebral Ischemia/Reperfusion Injury in Rats through a Mechanism Targeting Aquaporin 4

(2015) Lin Lu et al.   Evidence-based Complementary and Alternative Medicine

Mildly Reduced Brain Swelling and Improved Neurological Outcome in Aquaporin-4 Knockout Mice following Controlled Cortical Impact Brain Injury

(2015) Xiaoming Yao et al.   JOURNAL OF NEUROTRAUMA

Reduced brain edema and infarct volume in aquaporin-4 deficient mice after transient focal cerebral ischemia

(2015) Xiaoming Yao et al.   NEUROSCIENCE LETTERS

Ginseng: a promising neuroprotective strategy in stroke

(2015) Vaibhav Rastogi et al.   Frontiers in Cellular Neuroscience

Protective effect of ginsenoside Rb1 on integrity of blood–brain barrier following cerebral ischemia

(2015) Wei Chen et al.   EXPERIMENTAL BRAIN RESEARCH

Secondary Prevention after Ischemic Stroke or Transient Ischemic Attack

(2014) Sripal Bangalore et al.   AMERICAN JOURNAL OF MEDICINE

Ginsenosides: prospective for sustainable biotechnological production

(2014) Hosakatte Niranjana Murthy et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Blood-Brain Barrier Is Not a Barrier in the Development of New Drugs for Ischemic Stroke

(2014) Wei-Ye Liu et al.   CNS Neuroscience & Therapeutics

Rhubarb root and rhizome-based Chinese herbal prescriptions for acute ischemic stroke: A systematic review and meta-analysis

(2014) Lin Lu et al.   COMPLEMENTARY THERAPIES IN MEDICINE

Ginsenoside Rg1 provides neuroprotection against blood brain barrier disruption and neurological injury in a rat model of cerebral ischemia/reperfusion through downregulation of aquaporin 4 expression

(2014) Yun Zhou et al.   PHYTOMEDICINE

Gap Junction Intercellular Communication Mediated by Connexin43 in Astrocytes Is Essential for Their Resistance to Oxidative Stress

(2013) Hoa T. Le et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Development, maintenance and disruption of the blood-brain barrier

(2013) Birgit Obermeier et al.   NATURE MEDICINE

Aquaporin water channels in the nervous system

(2013) Marios C. Papadopoulos et al.   NATURE REVIEWS NEUROSCIENCE

Antisense oligodeoxynucleotides targeting connexin43 reduce cerebral astrocytosis and edema in a rat model of traumatic brain injury

(2013) Zhongliang Wu et al.   NEUROLOGICAL RESEARCH

Guidelines for the Early Management of Patients With Acute Ischemic Stroke

(2013) Edward C. Jauch et al.   STROKE

Compatibility art of traditional Chinese medicine: From the perspective of herb pairs

(2012) Shengpeng Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Neuronal gap junctions: making and breaking connections during development and injury

(2012) Andrei B. Belousov et al.   TRENDS IN NEUROSCIENCES

Caveolin-1 regulates nitric oxide-mediated matrix metalloproteinases activity and blood-brain barrier permeability in focal cerebral ischemia and reperfusion injury

(2011) Yong Gu et al.   JOURNAL OF NEUROCHEMISTRY

Thrombolysis at 3–4.5 Hours after Acute Ischemic Stroke Onset – Evidence from the Canadian Alteplase for Stroke Effectiveness Study (CASES) Registry

(2010) Nandavar Shobha et al.   CEREBROVASCULAR DISEASES

The complexity of neurobiological processes in acute ischemic stroke

(2009) R. Brouns et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

Gene expression profiling of astrocytes from hyperammonemic mice reveals altered pathways for water and potassium homeostasisin vivo

(2008) Uta Lichter-Konecki et al.   GLIA

AQP4 knockout impairs proliferation, migration and neuronal differentiation of adult neural stem cells

(2008) H. Kong et al.   JOURNAL OF CELL SCIENCE

Aggravation of infarct formation by brain swelling in a large territorial stroke: a target for neuroprotection?

(2008) Maureen Walberer et al.   JOURNAL OF NEUROSURGERY