Regulation of IL-6 Secretion by Astrocytes via TLR4 in the Fragile X Mouse Model

Mapping tenascin-C interaction with toll-like receptor 4 reveals a new subset of endogenous inflammatory triggers

(2017) Lorena Zuliani-Alvarez et al.   Nature Communications

Altered Developmental Expression of the Astrocyte-Secreted Factors Hevin and SPARC in the Fragile X Mouse Model

(2017) Jessica Wallingford et al.   Frontiers in Molecular Neuroscience

The extracellular matrix glycoprotein tenascin-C and matrix metalloproteinases modify cerebellar structural plasticity by exposure to an enriched environment

(2016) Vera Stamenkovic et al.   Brain Structure & Function

FMRP Expression Levels in Mouse Central Nervous System Neurons Determine Behavioral Phenotype

(2016) Jason Arsenault et al.   HUMAN GENE THERAPY

Postnatal activation of TLR4 in astrocytes promotes excitatory synaptogenesis in hippocampal neurons

(2016) Yi Shen et al.   JOURNAL OF CELL BIOLOGY

Deficiency of tenascin-C and attenuation of blood-brain barrier disruption following experimental subarachnoid hemorrhage in mice

(2016) Masashi Fujimoto et al.   JOURNAL OF NEUROSURGERY

Astrocyte-secreted thrombospondin-1 modulates synapse and spine defects in the fragile X mouse model

(2016) Connie Cheng et al.   Molecular Brain

Synaptic Plasticity, a Prominent Contributor to the Anxiety in Fragile X Syndrome

(2016) Tao Yang et al.   NEURAL PLASTICITY

Altered Neuronal and Circuit Excitability in Fragile X Syndrome

(2015) Anis Contractor et al.   NEURON

Astrocytes Control Synapse Formation, Function, and Elimination

(2015) Won-Suk Chung et al.   Cold Spring Harbor Perspectives in Biology

Persistent astrocyte activation in the fragile X mouse cerebellum

(2015) Laura K. K. Pacey et al.   Brain and Behavior

Biological role of Toll-like receptor-4 in the brain

(2014) Teresa Trotta et al.   JOURNAL OF NEUROIMMUNOLOGY

Fmr1 KO and Fenobam Treatment Differentially Impact Distinct Synapse Populations of Mouse Neocortex

(2014) Gordon X. Wang et al.   NEURON

Astrocyte-Secreted Matricellular Proteins in CNS Remodelling during Development and Disease

(2014) Emma V. Jones et al.   NEURAL PLASTICITY

The role of cell adhesion molecules (CAMs) in defining synapse-specific function and plasticity

(2013) Seung-Hee Lee et al.   Animal Cells and Systems

Brain IL-6 and autism

(2013) H. Wei et al.   NEUROSCIENCE

Brain IL-6 elevation causes neuronal circuitry imbalances and mediates autism-like behaviors

(2012) Hongen Wei et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Astrocytes and Developmental Plasticity in Fragile X

(2012) Connie Cheng et al.   NEURAL PLASTICITY

Toll-like Receptor Expression and Activation in Astroglia: Differential Regulation by HIV-1 Tat, gp120, and Morphine

(2011) Nazira El-Hage et al.   IMMUNOLOGICAL INVESTIGATIONS

IL-6 is increased in the cerebellum of autistic brain and alters neural cell adhesion, migration and synaptic formation

(2011) Hongen Wei et al.   Journal of Neuroinflammation

A stabilising influence: Integrins in regulation of synaptic plasticity

(2011) Andrew B. McGeachie et al.   NEUROSCIENCE RESEARCH

Evidence of reactive astrocytes but not peripheral immune system activation in a mouse model of Fragile X syndrome

(2010) Christopher J. Yuskaitis et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Contributions of astrocytes to synapse formation and maturation — Potential functions of the perisynaptic extracellular matrix

(2010) Andreas Faissner et al.   BRAIN RESEARCH REVIEWS

Astrocyte TLR4 activation induces a proinflammatory environment through the interplay between MyD88-dependent NFκB signaling, MAPK, and Jak1/Stat1 pathways

(2010) Roser Gorina et al.   GLIA

IL-6 Trans-Signaling Modulates TLR4-Dependent Inflammatory Responses via STAT3

(2010) C. J. Greenhill et al.   JOURNAL OF IMMUNOLOGY

Astrocytes Prevent Abnormal Neuronal Development in the Fragile X Mouse

(2010) S. Jacobs et al.   JOURNAL OF NEUROSCIENCE

Extracellular Matrix: Functions in the Nervous System

(2010) C. S. Barros et al.   Cold Spring Harbor Perspectives in Biology

Lipopolysaccharide-induced interleukin-6 production is controlled by glycogen synthase kinase-3 and STAT3 in the brain

(2009) Eléonore Beurel et al.   Journal of Neuroinflammation

STAT3 tyrosine phosphorylation is critical for interleukin 1 beta and interleukin-6 production in response to lipopolysaccharide and live bacteria

(2009) Lobelia Samavati et al.   MOLECULAR IMMUNOLOGY

Tenascin-C is an endogenous activator of Toll-like receptor 4 that is essential for maintaining inflammation in arthritic joint disease

(2009) Kim Midwood et al.   NATURE MEDICINE

The State of Synapses in Fragile X Syndrome

(2009) Brad E. Pfeiffer et al.   NEUROSCIENTIST