Interleukin-6 Receptor Blockade Enhances CD39+ Regulatory T Cell Development in Rheumatoid Arthritis and in Experimental Arthritis

Adoptive Transfer of Human Gingiva-Derived Mesenchymal Stem Cells Ameliorates Collagen-Induced Arthritis via Suppression of Th1 and Th17 Cells and Enhancement of Regulatory T Cell Differentiation

(2013) Maogen Chen et al.   ARTHRITIS AND RHEUMATISM

Induced CD4+Foxp3+ Regulatory T Cells in Immune Tolerance

(2012) Angelina M. Bilate et al.   Annual Review of Immunology

Brief Report: Inhibition of interleukin-6 function corrects Th17/Treg cell imbalance in patients with rheumatoid arthritis

(2012) Maxime Samson et al.   ARTHRITIS AND RHEUMATISM

Response to Comment on "Expression of Helios in Peripherally Induced Foxp3+ Regulatory T Cells"

(2012) R. A. Gottschalk et al.   JOURNAL OF IMMUNOLOGY

Alterations in the adenosine metabolism and CD39/CD73 adenosinergic machinery cause loss of Treg cell function and autoimmunity in ADA-deficient SCID

(2011) A. V. Sauer et al.   BLOOD

Immunotherapeutic implication of IL-6 blockade

(2011) Toshio Tanaka et al.   Immunotherapy

TNFα: Activator or inhibitor of regulatory T cells?

(2011) Jérôme Biton et al.   JOINT BONE SPINE

Segregated Regulatory CD39+CD4+ T Cell Function: TGF- -Producing Foxp3- and IL-10-Producing Foxp3+ Cells Are Interdependent for Protection against Collagen-Induced Arthritis

(2011) I. Kochetkova et al.   JOURNAL OF IMMUNOLOGY

Interplay between TNF and Regulatory T Cells in a TNF-Driven Murine Model of Arthritis

(2011) Jérôme Biton et al.   JOURNAL OF IMMUNOLOGY

Helios Expression Is a Marker of T Cell Activation and Proliferation

(2011) Tatiana Akimova et al.   PLoS One

2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative

(2010) Daniel Aletaha et al.   ARTHRITIS AND RHEUMATISM

Blockade of interleukin-6 signaling suppresses experimental autoimmune uveoretinitis by the inhibition of inflammatory Th17 responses

(2010) Satoshi Hohki et al.   EXPERIMENTAL EYE RESEARCH

Cell and cytokine imbalances in rheumatoid synovitis

(2010) Marie-Christophe Boissier   JOINT BONE SPINE

Blocking of IL-6 suppresses experimental autoimmune myasthenia gravis

(2010) Revital Aricha et al.   JOURNAL OF AUTOIMMUNITY

Although IL-6 Trans-Signaling Is Sufficient To Drive Local Immune Responses, Classical IL-6 Signaling Is Obligate for the Induction of T Cell-Mediated Autoimmunity

(2010) R. Lissilaa et al.   JOURNAL OF IMMUNOLOGY

IL-35 Stimulation of CD39+ Regulatory T Cells Confers Protection against Collagen II-Induced Arthritis via the Production of IL-10

(2010) I. Kochetkova et al.   JOURNAL OF IMMUNOLOGY

Expression of Helios, an Ikaros Transcription Factor Family Member, Differentiates Thymic-Derived from Peripherally Induced Foxp3+ T Regulatory Cells

(2010) A. M. Thornton et al.   JOURNAL OF IMMUNOLOGY

IL-6 blockade preferentially inhibits Th17 differentiation in collagen-induced arthritis

(2010) Hiroto Yoshida et al.   RHEUMATOLOGY INTERNATIONAL

Proinflammatory role of the Th17 cytokine interleukin-22 in collagen-induced arthritis in C57BL/6 mice

(2009) Lies Geboes et al.   ARTHRITIS AND RHEUMATISM

The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4+T cells

(2009) Oliver Dienz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CD39+Foxp3+ Regulatory T Cells Suppress Pathogenic Th17 Cells and Are Impaired in Multiple Sclerosis

(2009) J. M. Fletcher et al.   JOURNAL OF IMMUNOLOGY

Interleukin-6 blockade suppresses autoimmune arthritis in mice by the inhibition of inflammatory Th17 responses

(2008) Minoru Fujimoto et al.   ARTHRITIS AND RHEUMATISM

Crucial role of the interleukin-6/interleukin-17 cytokine axis in the induction of arthritis by glucose-6-phosphate isomerase

(2008) Keiichi Iwanami et al.   ARTHRITIS AND RHEUMATISM

IL-6 blockade inhibits the induction of myelin antigen-specific Th17 cells and Th1 cells in experimental autoimmune encephalomyelitis

(2008) Satoshi Serada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Defects in CTLA-4 are associated with abnormal regulatory T cell function in rheumatoid arthritis

(2008) F. Flores-Borja et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA