Alterations in the adenosine metabolism and CD39/CD73 adenosinergic machinery cause loss of Treg cell function and autoimmunity in ADA-deficient SCID

Lentiviral-mediated gene therapy leads to improvement of B-cell functionality in a murine model of Wiskott-Aldrich syndrome

(2011) Marita Bosticardo et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

ATP Inhibits the Generation and Function of Regulatory T Cells Through the Activation of Purinergic P2X Receptors

(2011) U. Schenk et al.   Science Signaling

Defect of regulatory T cells in patients with Omenn syndrome

(2010) Barbara Cassani et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

cAMP/CREB-mediated Transcriptional Regulation of Ectonucleoside Triphosphate Diphosphohydrolase 1 (CD39) Expression

(2010) Hui Liao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Homeostatic expansion of autoreactive immunoglobulin-secreting cells in theRag2mouse model of Omenn syndrome

(2010) Barbara Cassani et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Different Extent of B and T Cell Immune Reconstitution after Hematopoietic Stem Cell Transplantation and Enzyme Replacement Therapies in SCID Patients with Adenosine Deaminase Deficiency

(2010) F. Serana et al.   JOURNAL OF IMMUNOLOGY

Long-term outcome after hematopoietic stem cell transplantation of a single-center cohort of 90 patients with severe combined immunodeficiency

(2009) B. Neven et al.   BLOOD

ADA-deficient SCID is associated with a specific microenvironment and bone phenotype characterized by RANKL/OPG imbalance and osteoblast insufficiency

(2009) A. V. Sauer et al.   BLOOD

How I treat ADA deficiency

(2009) H. B. Gaspar et al.   BLOOD

New insights into the pathogenesis of adenosine deaminase-severe combined immunodeficiency and progress in gene therapy

(2009) Aisha V Sauer et al.   Current Opinion in Allergy and Clinical Immunology

Generation and Accumulation of Immunosuppressive Adenosine by Human CD4+CD25highFOXP3+Regulatory T Cells

(2009) Magis Mandapathil et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gene Therapy for Immunodeficiency Due to Adenosine Deaminase Deficiency

(2009) Alessandro Aiuti et al.   NEW ENGLAND JOURNAL OF MEDICINE

Regulatory T Cells and Immune Tolerance

(2008) Shimon Sakaguchi et al.   CELL

Homeostasis of Naive and Memory T Cells

(2008) Charles D. Surh et al.   IMMUNITY

Single-center analysis of long-term outcome after hematopoietic cell transplantation in children with congenital severe T cell immunodeficiency

(2008) Evelina Mazzolari et al.   IMMUNOLOGIC RESEARCH

Apoptosis as a mechanism of T-regulatory cell homeostasis and suppression

(2008) Esma S Yolcu et al.   IMMUNOLOGY AND CELL BIOLOGY

Adenosine receptors: therapeutic aspects for inflammatory and immune diseases

(2008) György Haskó et al.   NATURE REVIEWS DRUG DISCOVERY