Contribution of Mast Cell-Derived Interleukin-1β to Uric Acid Crystal-Induced Acute Arthritis in Mice

Human mast cells drive memory CD4+ T cells toward an inflammatory IL-22+ phenotype

(2013) Nicolas Gaudenzio et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Selective ablation of mast cells or basophils reduces peanut-induced anaphylaxis in mice

(2013) Laurent L. Reber et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Role of Interleukin-1 Inhibitors in the Management of Gout

(2013) Tran H. Tran et al.   PHARMACOTHERAPY

Rilonacept (Interleukin-1 Trap) in the prevention of acute gout flares during initiation of urate-lowering therapy: Results of a phase II randomized, double-blind, placebo-controlled trial

(2012) H. Ralph Schumacher et al.   ARTHRITIS AND RHEUMATISM

Critical Role for Mast Cells in Interleukin-1β-Driven Skin Inflammation Associated with an Activating Mutation in the Nlrp3 Protein

(2012) Yuumi Nakamura et al.   IMMUNITY

Inflammasome Activators Induce Interleukin-1α Secretion via Distinct Pathways with Differential Requirement for the Protease Function of Caspase-1

(2012) Olaf Groß et al.   IMMUNITY

Inflammasomes in health and disease

(2012) Till Strowig et al.   NATURE

Uric acid as a danger signal in gout and its comorbidities

(2012) Kenneth L. Rock et al.   Nature Reviews Rheumatology

New models for analyzing mast cell functions in vivo

(2012) Laurent L. Reber et al.   TRENDS IN IMMUNOLOGY

Neutrophil-derived IL-1β Is Sufficient for Abscess Formation in Immunity against Staphylococcus aureus in Mice

(2012) John S. Cho et al.   PLoS Pathogens

NLRP3 inflammasome-mediated neutrophil recruitment and hypernociception depend on leukotriene B4 in a murine model of gout

(2011) Flávio A. Amaral et al.   ARTHRITIS AND RHEUMATISM

Reduced mast cell and basophil numbers and function in Cpa3-Cre; Mcl-1fl/fl mice

(2011) J. N. Lilla et al.   BLOOD

Mast Cell Interleukin-2 Production Contributes to Suppression of Chronic Allergic Dermatitis

(2011) Alon Y. Hershko et al.   IMMUNITY

Cre-Mediated Cell Ablation Contests Mast Cell Contribution in Models of Antibody- and T Cell-Mediated Autoimmunity

(2011) Thorsten B. Feyerabend et al.   IMMUNITY

Progress and controversies in treatment

(2011) Nicola Dalbeth   Nature Reviews Rheumatology

Bone destruction by receptor activator of nuclear factor κB ligand-expressing T cells in chronic gouty arthritis

(2011) Sung-Ji Lee et al.   ARTHRITIS RESEARCH & THERAPY

How interleukin-1β induces gouty arthritis

(2010) Charles A. Dinarello   ARTHRITIS AND RHEUMATISM

Engagement of fatty acids with toll-like receptor 2 drives interleukin-1β production via the ASC/caspase 1 pathway in monosodium urate monohydrate crystal-induced gouty arthritis

(2010) Leo A. B. Joosten et al.   ARTHRITIS AND RHEUMATISM

Serum total tryptase levels are increased in patients with active chronic urticaria

(2010) M. Ferrer et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Selective ablation of basophils in mice reveals their nonredundant role in acquired immunity against ticks

(2010) Takeshi Wada et al.   JOURNAL OF CLINICAL INVESTIGATION

The NLRP3 Inflammasome: A Sensor for Metabolic Danger?

(2010) K. Schroder et al.   SCIENCE

Mast Cell-Derived TNF Can Exacerbate Mortality during Severe Bacterial Infections in C57BL/6-KitW-sh/W-sh Mice

(2009) Adrian M. Piliponsky et al.   AMERICAN JOURNAL OF PATHOLOGY

Resident macrophages initiating and driving inflammation in a monosodium urate monohydrate crystal-induced murine peritoneal model of acute gout

(2009) William John Martin et al.   ARTHRITIS AND RHEUMATISM

Mast cells mediate neutrophil recruitment and vascular leakage through the NLRP3 inflammasome in histamine-independent urticaria

(2009) Yuumi Nakamura et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors

(2009) François Ghiringhelli et al.   NATURE MEDICINE