Co-infection withMycobacterium tuberculosisand human immunodeficiency virus: an overview and motivation for systems approaches

The Immune Response in Tuberculosis

(2013) Anne O'Garra et al.   Annual Review of Immunology

Susceptibility to Mycobacterium tuberculosis Infection in HIV-Positive Patients Is Associated With CARD8 Genetic Variant

(2013) Alessandra Pontillo et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Host Responses to Melioidosis and Tuberculosis Are Both Dominated by Interferon-Mediated Signaling

(2013) Gavin C. K. W. Koh et al.   PLoS One

Genomic responses in mouse models poorly mimic human inflammatory diseases

(2013) Junhee Seok et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HIV Infection Disrupts the Sympatric Host–Pathogen Relationship in Human Tuberculosis

(2013) Lukas Fenner et al.   PLoS Genetics

Corticosteroid-modulated Immune Activation in the Tuberculosis Immune Reconstitution Inflammatory Syndrome

(2012) Graeme Meintjes et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Natural killer cell degranulation capacity predicts early onset of the immune reconstitution inflammatory syndrome (IRIS) in HIV-infected patients with tuberculosis

(2012) P. Pean et al.   BLOOD

Risk of Progression to Active Tuberculosis Following Reinfection With Mycobacterium tuberculosis

(2012) Jason R. Andrews et al.   CLINICAL INFECTIOUS DISEASES

IL-10 high producing genotype predisposes HIV infected individuals to TB infection

(2012) Sharada Ramaseri Sunder et al.   HUMAN IMMUNOLOGY

Understanding TB latency using computational and dynamic modelling procedures

(2012) Gesham Magombedze et al.   INFECTION GENETICS AND EVOLUTION

The non-human primate model of tuberculosis

(2012) D. Kaushal et al.   JOURNAL OF MEDICAL PRIMATOLOGY

An integrated map of genetic variation from 1,092 human genomes

(2012)   NATURE

Common variants at 11p13 are associated with susceptibility to tuberculosis

(2012) Thorsten Thye et al.   NATURE GENETICS

Dual RNA-seq of pathogen and host

(2012) Alexander J. Westermann et al.   NATURE REVIEWS MICROBIOLOGY

Host-pathogen coevolution in human tuberculosis

(2012) S. Gagneux   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Annotation of the M. tuberculosis Hypothetical Orfeome: Adding Functional Information to More than Half of the Uncharacterized Proteins

(2012) Tobias Doerks et al.   PLoS One

Genome-Wide Expression Profiling Identifies Type 1 Interferon Response Pathways in Active Tuberculosis

(2012) Tom H. M. Ottenhoff et al.   PLoS One

Detectable Changes in The Blood Transcriptome Are Present after Two Weeks of Antituberculosis Therapy

(2012) Chloe I. Bloom et al.   PLoS One

Deciphering the genetic architecture of variation in the immune response to Mycobacterium tuberculosis infection

(2012) L. B. Barreiro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of P-TEFb at Sites of Dual HIV/TB Infection, and Inhibition of MTB-Induced HIV Transcriptional Activation by the Inhibitor of CDK9, Indirubin-3′-Monoxime

(2011) Zahra Toossi et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

HIV and Tuberculosis: a Deadly Human Syndemic

(2011) C. K. Kwan et al.   CLINICAL MICROBIOLOGY REVIEWS

HIV-1 infection alters CD4+memory T-cell phenotype at the site of disease in extrapulmonary tuberculosis

(2011) Kerryn Matthews et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Interferon release does not add discriminatory value to smear-negative HIV-tuberculosis algorithms

(2011) M. X. Rangaka et al.   EUROPEAN RESPIRATORY JOURNAL

HIV-1/Mycobacterium tuberculosisCoinfection Immunology: How Does HIV-1 Exacerbate Tuberculosis?

(2011) Collin R. Diedrich et al.   INFECTION AND IMMUNITY

Contribution of microarray data to the advancement of knowledge on the Mycobacterium tuberculosis interactome: Use of the random partial least squares approach

(2011) Gaston K. Mazandu et al.   INFECTION GENETICS AND EVOLUTION

A hybrid multi-compartment model of granuloma formation and T cell priming in Tuberculosis

(2011) Simeone Marino et al.   JOURNAL OF THEORETICAL BIOLOGY

Natural History of Tuberculosis: Duration and Fatality of Untreated Pulmonary Tuberculosis in HIV Negative Patients: A Systematic Review

(2011) Edine W. Tiemersma et al.   PLoS One

Scoring Protein Relationships in Functional Interaction Networks Predicted from Sequence Data

(2011) Gaston K. Mazandu et al.   PLoS One

The utility of the new generation of humanized mice to study HIV-1 infection: transmission, prevention, pathogenesis, and treatment

(2011) Bradford K Berges et al.   Retrovirology

High prevalence of subclinical tuberculosis in HIV-1-infected persons without advanced immunodeficiency: implications for TB screening

(2011) T. Oni et al.   THORAX

A role for systems epidemiology in tuberculosis research

(2011) Iñaki Comas et al.   TRENDS IN MICROBIOLOGY

A Systems Biology Approach to Infectious Disease Research: Innovating the Pathogen-Host Research Paradigm

(2011) A. Aderem et al.   mBio

A multifaceted approach to modeling the immune response in tuberculosis

(2011) Simeone Marino et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Genetic Epidemiology of Tuberculosis Susceptibility: Impact of Study Design

(2011) Catherine M. Stein   PLoS Pathogens

Assessing the human immune system through blood transcriptomics

(2010) Damien Chaussabel et al.   BMC BIOLOGY

Genome-wide Analysis of the Host Intracellular Network that Regulates Survival of Mycobacterium tuberculosis

(2010) Dhiraj Kumar et al.   CELL

HIV Infection–Related Tuberculosis: Clinical Manifestations and Treatment

(2010) Timothy R. Sterling et al.   CLINICAL INFECTIOUS DISEASES

Clinical management of tuberculosis and HIV-1 co-infection

(2010) C. Schutz et al.   EUROPEAN RESPIRATORY JOURNAL

Hypercytokinaemia accompanies HIV-tuberculosis immune reconstitution inflammatory syndrome

(2010) R. Tadokera et al.   EUROPEAN RESPIRATORY JOURNAL

Human gene expression profiles of susceptibility and resistance in tuberculosis

(2010) J Maertzdorf et al.   GENES AND IMMUNITY

An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis

(2010) Matthew P. R. Berry et al.   NATURE

Cell type–specific gene expression differences in complex tissues

(2010) Shai S Shen-Orr et al.   NATURE METHODS

Systemic Administration of Antiretrovirals Prior to Exposure Prevents Rectal and Intravenous HIV-1 Transmission in Humanized BLT Mice

(2010) Paul W. Denton et al.   PLoS One

Short-term and long-term risk of tuberculosis associated with CD4 cell recovery during antiretroviral therapy in South Africa

(2009) Stephen D Lawn et al.   AIDS

Dissection of Regenerating T-Cell Responses against Tuberculosis in HIV-infected Adults Sensitized byMycobacterium tuberculosis

(2009) Katalin A. Wilkinson et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

HIV-1 Infection Impairs the Bronchoalveolar T-Cell Response to Mycobacteria

(2009) Barbara Kalsdorf et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Incomplete Reconstitution of T Cell Subsets on Combination Antiretroviral Therapy in the AIDS Clinical Trials Group Protocol 384

(2009) Gregory K. Robbins et al.   CLINICAL INFECTIOUS DISEASES

Proliferation of weakly suppressive regulatory CD4+ T cells is associated with over-active CD4+ T-cell responses in HIV-positive patients with mycobacterial immune restoration disease

(2009) Nabila Seddiki et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Past, present and future directions in human genetic susceptibility to tuberculosis

(2009) Marlo Möller et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Anti-TNF immunotherapy reduces CD8+ T cell–mediated antimicrobial activity against Mycobacterium tuberculosis in humans

(2009) Heiko Bruns et al.   JOURNAL OF CLINICAL INVESTIGATION

Tuberculosis-Associated Immune Restoration Syndrome in HIV-1-Infected Patients Involves Tuberculin-Specific CD4 Th1 Cells and KIR-Negative    T Cells

(2009) A. Bourgarit et al.   JOURNAL OF IMMUNOLOGY

Selective Expression of Human Immunodeficiency Virus Nef in Specific Immune Cell Populations of Transgenic Mice Is Associated with Distinct AIDS-Like Phenotypes

(2009) Z. Hanna et al.   JOURNAL OF VIROLOGY

Deconvolution of Blood Microarray Data Identifies Cellular Activation Patterns in Systemic Lupus Erythematosus

(2009) Alexander R. Abbas et al.   PLoS One

A Critical Role for CD8 T Cells in a Nonhuman Primate Model of Tuberculosis

(2009) Crystal Y. Chen et al.   PLoS Pathogens

Fatal unmasking tuberculosis immune reconstitution disease with bronchiolitis obliterans organizing pneumonia: the role of macrophages

(2008) Stephen D Lawn et al.   AIDS

Type 1 Helper T Cells and FoxP3-positive T Cells in HIV–Tuberculosis-associated Immune Reconstitution Inflammatory Syndrome

(2008) Graeme Meintjes et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

A Modular Analysis Framework for Blood Genomics Studies: Application to Systemic Lupus Erythematosus

(2008) Damien Chaussabel et al.   IMMUNITY

Systems biology of innate immunity

(2008) Daniel E. Zak et al.   IMMUNOLOGICAL REVIEWS

Mycobacterial T Cell Responses in HIV‐Infected Patients with Advanced Immunosuppression

(2008) Abdulrahman S. Hammond et al.   JOURNAL OF INFECTIOUS DISEASES

Early Depletion ofMycobacterium tuberculosis–Specific T Helper 1 Cell Responses after HIV‐1 Infection

(2008) Christof Geldmacher et al.   JOURNAL OF INFECTIOUS DISEASES

Systems biology of persistent infection: tuberculosis as a case study

(2008) Douglas Young et al.   NATURE REVIEWS MICROBIOLOGY

Antiretroviral Pre-exposure Prophylaxis Prevents Vaginal Transmission of HIV-1 in Humanized BLT Mice

(2008) Paul W Denton et al.   PLOS MEDICINE