Pathology and function of nuclear amyloid

Biophysical Underpinnings of the Repeat Length Dependence of Polyglutamine Amyloid Formation

(2014) Elizabeth Landrum et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effect of Nanoparticles on the Biochemical and Behavioral Aging Phenotype of the Nematode Caenorhabditis elegans

(2013) Andrea Scharf et al.   ACS Nano

Biology and Genetics of Prions Causing Neurodegeneration

(2013) Stanley B. Prusiner   Annual Review of Genetics

PolyQ Proteins Interfere with Nuclear Degradation of Cytosolic Proteins by Sequestering the Sis1p Chaperone

(2013) Sae-Hun Park et al.   CELL

Centenary of Lewy bodies (1912–2012)

(2013) Bernd Holdorff et al.   JOURNAL OF NEURAL TRANSMISSION

Structural visualization of key steps in human transcription initiation

(2013) Yuan He et al.   NATURE

Proteostasis of polyglutamine varies among neurons and predicts neurodegeneration

(2013) Andrey S Tsvetkov et al.   Nature Chemical Biology

Biomarker Modeling of Alzheimer’s Disease

(2013) Clifford R. Jack et al.   NEURON

Chemical Strategies for Controlling Protein Folding and Elucidating the Molecular Mechanisms of Amyloid Formation and Toxicity

(2012) Sara Butterfield et al.   JOURNAL OF MOLECULAR BIOLOGY

Evolution and function of CAG/polyglutamine repeats in protein–protein interaction networks

(2012) Martin H. Schaefer et al.   NUCLEIC ACIDS RESEARCH

Amyloid-like Aggregates Sequester Numerous Metastable Proteins with Essential Cellular Functions

(2011) Heidi Olzscha et al.   CELL

Quantitative feature extraction reveals the status quo of protein fibrillation in the cell nucleus

(2011) Florian Arnhold et al.   Integrative Biology

Intranuclear inclusions in epithelial cells of benign proliferative breast lesions

(2011) O. Harada et al.   JOURNAL OF CLINICAL PATHOLOGY

Axonal inclusions in spinocerebellar ataxia type 3

(2010) Kay Seidel et al.   ACTA NEUROPATHOLOGICA

Dynamic as well as stable protein interactions contribute to genome function and maintenance

(2010) Peter Hemmerich et al.   CHROMOSOME RESEARCH

Targeting intrinsically disordered proteins in neurodegenerative and protein dysfunction diseases: another illustration of the D2concept

(2010) Vladimir N Uversky   Expert Review of Proteomics

B2 attenuates polyglutamine-expanded androgen receptor toxicity in cell and fly models of spinal and bulbar muscular atrophy

(2010) Isabella Palazzolo et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Huntington's disease: from molecular pathogenesis to clinical treatment

(2010) Christopher A Ross et al.   LANCET NEUROLOGY

Novel Pentameric Thiophene Derivatives forin Vitroandin VivoOptical Imaging of a Plethora of Protein Aggregates in Cerebral Amyloidoses

(2009) Andreas Åslund et al.   ACS Chemical Biology

Structural integrity of β-sheet assembly

(2009) Karen E. Marshall et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Transcriptional dysregulation of coding and non-coding genes in cellular models of Huntington's disease

(2009) Angela Bithell et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

SUMOylation attenuates the aggregation propensity and cellular toxicity of the polyglutamine expanded ataxin-7

(2009) Alexandre Janer et al.   HUMAN MOLECULAR GENETICS

Monoclonal Antibodies Recognize Distinct Conformational Epitopes Formed by Polyglutamine in a Mutant Huntingtin Fragment

(2009) Justin Legleiter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional Amyloids As Natural Storage of Peptide Hormones in Pituitary Secretory Granules

(2009) S. K. Maji et al.   SCIENCE

PolyQ fibrillation in the cell nucleus: who's bad?

(2009) Anna von Mikecz   TRENDS IN CELL BIOLOGY

Macromolecular Crowding and Confinement: Biochemical, Biophysical, and Potential Physiological Consequences

(2008) Huan-Xiang Zhou et al.   Annual Review of Biophysics

Targeting Proteins for Destruction by the Ubiquitin System: Implications for Human Pathobiology

(2008) Alan L. Schwartz et al.   Annual Review of Pharmacology and Toxicology

Nuclear polyglutamine-containing protein aggregates as active proteolytic centers

(2008) Min Chen et al.   JOURNAL OF CELL BIOLOGY

Amyloid formation by globular proteins under native conditions

(2008) Fabrizio Chiti et al.   Nature Chemical Biology

Polyglutamine neurodegeneration: protein misfolding revisited

(2008) Aislinn J. Williams et al.   TRENDS IN NEUROSCIENCES