The SLE Transcriptome Exhibits Evidence of Chronic Endotoxin Exposure and Has Widespread Dysregulation of Non-Coding and Coding RNAs

Polarization of Primary Human Monocytes by IFN-  Induces Chromatin Changes and Recruits RNA Pol II to the TNF-  Promoter

(2014) S. Garrett et al.   JOURNAL OF IMMUNOLOGY

IFN-  Skews Monocytes into CD56+-Expressing Dendritic Cells with Potent Functional Activities In Vitro and In Vivo

(2014) C. Papewalis et al.   JOURNAL OF IMMUNOLOGY

Activated Renal Macrophages Are Markers of Disease Onset and Disease Remission in Lupus Nephritis

(2014) L. Schiffer et al.   JOURNAL OF IMMUNOLOGY

TLR4 Ligands Induce IFN-  Production by Mouse Conventional Dendritic Cells and Human Monocytes after IFN-  Priming

(2014) C. Richez et al.   JOURNAL OF IMMUNOLOGY

Ubiquitously transcribed genes use alternative polyadenylation to achieve tissue-specific expression

(2013) S. Lianoglou et al.   GENES & DEVELOPMENT

Distinct Autoantibody Profiles in Systemic Lupus Erythematosus Patients are Selectively Associated with TLR7 and TLR9 Upregulation

(2013) Sudhir Kumar Chauhan et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Splicing factor SF2/ASF rescues IL-2 production in T cells from systemic lupus erythematosus patients by activating IL-2 transcription

(2013) V. R. Moulton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional genomics identifies type I interferon pathway as central for host defense against Candida albicans

(2013) Sanne P. Smeekens et al.   Nature Communications

Brief Report: Large-scale analysis of tumor necrosis factor α levels in systemic lupus erythematosus

(2012) Corinna E. Weckerle et al.   ARTHRITIS AND RHEUMATISM

Autoimmunity Initiates in Nonhematopoietic Cells and Progresses via Lymphocytes in an Interferon-Dependent Autoimmune Disease

(2012) Alevtina Gall et al.   IMMUNITY

PDTC attenuate LPS-induced kidney injury in systemic lupus erythematosus-prone MRL/lpr Mice

(2012) Jin-Xia Zhai et al.   MOLECULAR BIOLOGY REPORTS

Landscape of transcription in human cells

(2012) Sarah Djebali et al.   NATURE

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

(2012) Cole Trapnell et al.   Nature Protocols

Inhibition of polyadenylation reduces inflammatory gene induction

(2012) A. Kondrashov et al.   RNA

Interferon-alpha Subtype 11 Activates NK Cells and Enables Control of Retroviral Infection

(2012) Kathrin Gibbert et al.   PLoS Pathogens

Inhibition of miR-193a Expression by Max and RXR  Activates K-Ras and PLAU to Mediate Distinct Aspects of Cellular Transformation

(2011) D. Iliopoulos et al.   CANCER RESEARCH

The ubiquitin hydrolase USP22 contributes to 3′-end processing of JAK-STAT-inducible genes

(2011) Edmond Chipumuro et al.   FASEB JOURNAL

Monocyte polarization: the relationship of genome-wide changes in H4 acetylation with polarization

(2011) Z Zhang et al.   GENES AND IMMUNITY

Coordinated Post-transcriptional Regulation of Hsp70.3 Gene Expression by MicroRNA and Alternative Polyadenylation

(2011) Michael Tranter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Examining Associations of Circulating Endotoxin With Nutritional Status, Inflammation, and Mortality in Hemodialysis Patients

(2011) Usama Feroze et al.   JOURNAL OF RENAL NUTRITION

Transcriptional Activators Enhance Polyadenylation of mRNA Precursors

(2011) Takashi Nagaike et al.   MOLECULAR CELL

Antisense expression increases gene expression variability and locus interdependency

(2011) Z. Xu et al.   Molecular Systems Biology

Translocated LPS Might Cause Endotoxin Tolerance in Circulating Monocytes of Cystic Fibrosis Patients

(2011) Rosa del Campo et al.   PLoS One

miR-212 Increases Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand Sensitivity in Non–Small Cell Lung Cancer by Targeting the Antiapoptotic Protein PED

(2010) Mariarosaria Incoronato et al.   CANCER RESEARCH

Bacterial lipopolysaccharide enhances deposition of immune complexes and exacerbates nephritis in BXSB lupus-prone mice

(2010) N. A. GRANHOLM et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Alternative Splicing Factor/Splicing Factor 2 Regulates the Expression of the ζ Subunit of the Human T Cell Receptor-associated CD3 Complex

(2010) Vaishali R. Moulton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cytokine-Induced Monocyte Characteristics in SLE

(2010) Zhe Zhang et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Changes in Apoptotic Gene Expression in Lymphocytes from Rheumatoid Arthritis and Systemic Lupus Erythematosus Patients Compared with Healthy Lymphocytes

(2010) Paul Eggleton et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Microbial Translocation Correlates with the Severity of Both HIV‐1 and HIV‐2 Infections

(2010) Salma Nowroozalizadeh et al.   JOURNAL OF INFECTIOUS DISEASES

Macrophage activation and coronary atherosclerosis in systemic lupus erythematosus and rheumatoid arthritis

(2010) Young Hee Rho et al.   ARTHRITIS CARE & RESEARCH

Increased ERK and JNK activities correlate with disease activity in patients with systemic lupus erythematosus

(2009) Y Molad et al.   ANNALS OF THE RHEUMATIC DISEASES

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Widespread Shortening of 3′UTRs by Alternative Cleavage and Polyadenylation Activates Oncogenes in Cancer Cells

(2009) Christine Mayr et al.   CELL

Global H4 acetylation analysis by ChIP-chip in systemic lupus erythematosus monocytes

(2009) Z Zhang et al.   GENES AND IMMUNITY

Effects of interferon-beta therapy on innate and adaptive immune responses to the human endogenous retroviruses HERV-H and HERV-W, cytokine production, and the lectin complement activation pathway in multiple sclerosis

(2009) Thor Petersen et al.   JOURNAL OF NEUROIMMUNOLOGY

HIV-1 RNA Dysregulates the Natural TLR Response to Subclinical Endotoxemia in Kenyan Female Sex-Workers

(2009) Richard T. Lester et al.   PLoS One

Early onset of autoimmune disease by the retroviral integrase inhibitor raltegravir

(2009) G. B. Beck-Engeser et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ethnic and sex differences in circulating endotoxin levels: A novel marker of atherosclerotic and cardiovascular risk in a British multi-ethnic population

(2008) Michelle A. Miller et al.   ATHEROSCLEROSIS

Trex1 Prevents Cell-Intrinsic Initiation of Autoimmunity

(2008) Daniel B. Stetson et al.   CELL

Pathogenic Role of NF-κB Activation in Tubulointerstitial Inflammatory Lesions in Human Lupus Nephritis

(2008) Ling Zheng et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Circulating endotoxin and systemic immune activation in sporadic amyotrophic lateral sclerosis (sALS)

(2008) Rongzhen Zhang et al.   JOURNAL OF NEUROIMMUNOLOGY

Extracellular signal–regulated kinase 1/2 signalling in SLE T cells is influenced by oestrogen and disease activity

(2008) S Gorjestani et al.   LUPUS

Genome-Wide Analysis of MEF2 Transcriptional Program Reveals Synaptic Target Genes and Neuronal Activity-Dependent Polyadenylation Site Selection

(2008) Steven W. Flavell et al.   NEURON