Intranasal deferoxamine improves performance in radial arm water maze, stabilizes HIF-1α, and phosphorylates GSK3β in P301L tau transgenic mice

Brain Glucose Hypometabolism and Oxidative Stress in Preclinical Alzheimer's Disease

(2010) Lisa Mosconi et al.   Annals of the New York Academy of Sciences

Up-Regulation of Hypoxia-Inducible Factor (HIF)-1α and HIF-Target Genes in Cortical Neurons by the Novel Multifunctional Iron Chelator Anti-Alzheimer Drug, M30

(2010) Y. Avramovich-Tirosh et al.   Current Alzheimer Research

Novel drug targets based on metallobiology of Alzheimer's disease

(2010) Sanghamitra Bandyopadhyay et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

GSK3 signalling in neural development

(2010) Eun-Mi Hur et al.   NATURE REVIEWS NEUROSCIENCE

Long-chain 3-hydroxy fatty acids accumulating in LCHAD and MTP deficiencies induce oxidative stress in rat brain

(2010) Anelise M. Tonin et al.   NEUROCHEMISTRY INTERNATIONAL

The pattern of human tau phosphorylation is the result of priming and feedback events in primary hippocampal neurons

(2010) J. Bertrand et al.   NEUROSCIENCE

Dysregulation of Insulin Signaling, Glucose Transporters, O -GlcNAcylation, and Phosphorylation of Tau and Neurofilaments in the Brain

(2009) Yanqiu Deng et al.   AMERICAN JOURNAL OF PATHOLOGY

Central nervous insulin resistance: a promising target in the treatment of metabolic and cognitive disorders?

(2009) M. Hallschmid et al.   DIABETOLOGIA

Deferoxamine-induced neurite outgrowth and synapse formation in postnatal rat dorsal root ganglion (DRG) cell cultures

(2009) Marcin Nowicki et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

The induction of HIF-1 reduces astrocyte activation by amyloid beta peptide

(2009) David Schubert et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Intranasal delivery to the central nervous system: Mechanisms and experimental considerations

(2009) Shyeilla V. Dhuria et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Intranasal Deferoxamine Provides Increased Brain Exposure and Significant Protection in Rat Ischemic Stroke

(2009) L. R. Hanson et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Experimental Diabetes Mellitus Exacerbates Tau Pathology in a Transgenic Mouse Model of Alzheimer's Disease

(2009) Yazi D. Ke et al.   PLoS One

Iron Depletion by Deferoxamine Up-Regulates Glucose Uptake and Insulin Signaling in Hepatoma Cells and in Rat Liver

(2008) Paola Dongiovanni et al.   AMERICAN JOURNAL OF PATHOLOGY

Amyloid Activates GSK-3β to Aggravate Neuronal Tauopathy in Bigenic Mice

(2008) Dick Terwel et al.   AMERICAN JOURNAL OF PATHOLOGY

Promotion of osteogenesis through β-catenin signaling by desferrioxamine

(2008) Zhi-Hu Qu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The role of interleukin-1 in neuroinflammation and Alzheimer disease: an evolving perspective

(2008) Solomon S Shaftel et al.   Journal of Neuroinflammation

Intranasal drug targeting of hypocretin-1 (orexin-A) to the central nervous system

(2008) Shyeilla V. Dhuria et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Delivery of interferon-β to the monkey nervous system following intranasal administration

(2008) R.G. Thorne et al.   NEUROSCIENCE