Complexin inhibits spontaneous release and synchronizes Ca2+-triggered synaptic vesicle fusion by distinct mechanisms

Genetic analysis of the Complexin trans-clamping model for cross-linking SNARE complexes in vivo

(2014) R. W. Cho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Re-examining how complexin inhibits neurotransmitter release

(2014) Thorsten Trimbuch et al.   eLife

Studying protein-reconstituted proteoliposome fusion with content indicators in vitro

(2013) Jiajie Diao et al.   BIOESSAYS

Subtle Interplay between Synaptotagmin and Complexin Binding to the SNARE Complex

(2013) Junjie Xu et al.   JOURNAL OF MOLECULAR BIOLOGY

Complexin-1 Enhances the On-Rate of Vesicle Docking via Simultaneous SNARE and Membrane Interactions

(2013) Jiajie Diao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Neurotransmitter Release: The Last Millisecond in the Life of a Synaptic Vesicle

(2013) Thomas C. Südhof   NEURON

Fusion pore formation and expansion induced by Ca2+and synaptotagmin 1

(2013) Ying Lai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Native α-synuclein induces clustering of synaptic-vesicle mimics via binding to phospholipids and synaptobrevin-2/VAMP2

(2013) Jiajie Diao et al.   eLife

Complexin arrests a pool of docked vesicles for fast Ca2+-dependent release

(2012) Jörg Malsam et al.   EMBO JOURNAL

Complexin Controls Spontaneous and Evoked Neurotransmitter Release by Regulating the Timing and Properties of Synaptotagmin Activity

(2012) R. A. Jorquera et al.   JOURNAL OF NEUROSCIENCE

C-Terminal Complexin Sequence Is Selectively Required for Clamping and Priming But Not for Ca2+ Triggering of Synaptic Exocytosis

(2012) Y. J. Kaeser-Woo et al.   JOURNAL OF NEUROSCIENCE

Molecular machines governing exocytosis of synaptic vesicles

(2012) Reinhard Jahn et al.   NATURE

Studying calcium-triggered vesicle fusion in a single vesicle-vesicle content and lipid-mixing system

(2012) Minjoung Kyoung et al.   Nature Protocols

Reconstitution of the Vital Functions of Munc18 and Munc13 in Neurotransmitter Release

(2012) C. Ma et al.   SCIENCE

Synaptic proteins promote calcium-triggered fast transition from point contact to full fusion

(2012) Jiajie Diao et al.   eLife

A conformational switch in complexin is required for synaptotagmin to trigger synaptic fusion

(2011) Shyam S Krishnakumar et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Complexin cross-links prefusion SNAREs into a zigzag array

(2011) Daniel Kümmel et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Complexin activates and clamps SNAREpins by a common mechanism involving an intermediate energetic state

(2011) Feng Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

In vitro system capable of differentiating fast Ca2+-triggered content mixing from lipid exchange for mechanistic studies of neurotransmitter release

(2011) M. Kyoung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Binding of the complexin N terminus to the SNARE complex potentiates synaptic-vesicle fusogenicity

(2010) Mingshan Xue et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A single-vesicle content mixing assay for SNARE-mediated membrane fusion

(2010) Jiajie Diao et al.   Nature Communications

Tilting the Balance between Facilitatory and Inhibitory Functions of Mammalian and Drosophila Complexins Orchestrates Synaptic Vesicle Exocytosis

(2009) Mingshan Xue et al.   NEURON

Alternative Zippering as an On-Off Switch for SNARE-Mediated Fusion

(2009) C. G. Giraudo et al.   SCIENCE

Complexin Controls the Force Transfer from SNARE Complexes to Membranes in Fusion

(2009) A. Maximov et al.   SCIENCE

Membrane Fusion: Grappling with SNARE and SM Proteins

(2009) T. C. Sudhof et al.   SCIENCE

Complexin and Ca2+ stimulate SNARE-mediated membrane fusion

(2008) Tae-Young Yoon et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Construction and use of new cloning vectors for the rapid isolation of recombinant proteins from Escherichia coli

(2008) C.J. Rocco et al.   PLASMID

Accessory Proteins Stabilize the Acceptor Complex for Synaptobrevin, the 1:1 Syntaxin/SNAP-25 Complex

(2008) Keith Weninger et al.   STRUCTURE