In vitro system capable of differentiating fast Ca2+-triggered content mixing from lipid exchange for mechanistic studies of neurotransmitter release

RIM Proteins Tether Ca2+ Channels to Presynaptic Active Zones via a Direct PDZ-Domain Interaction

(2011) Pascal S. Kaeser et al.   CELL

Subnanometre single-molecule localization, registration and distance measurements

(2010) Alexandros Pertsinidis et al.   NATURE

Molecular mechanism of the synaptotagmin–SNARE interaction in Ca2+-triggered vesicle fusion

(2010) Marija Vrljic et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

One SNARE complex is sufficient for membrane fusion

(2010) Geert van den Bogaart et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Binding of the complexin N terminus to the SNARE complex potentiates synaptic-vesicle fusogenicity

(2010) Mingshan Xue et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis

(2010) Ok-Ho Shin et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Single-molecule FRET–derived model of the synaptotagmin 1–SNARE fusion complex

(2010) Ucheor B Choi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Complexin Clamps Asynchronous Release by Blocking a Secondary Ca2+ Sensor via Its Accessory α Helix

(2010) Xiaofei Yang et al.   NEURON

Dynamic Ca2+-Dependent Stimulation of Vesicle Fusion by Membrane-Anchored Synaptotagmin 1

(2010) H. K. Lee et al.   SCIENCE

A single-vesicle content mixing assay for SNARE-mediated membrane fusion

(2010) Jiajie Diao et al.   Nature Communications

Single-Molecule Studies of the Neuronal SNARE Fusion Machinery

(2009) Axel T. Brunger et al.   Annual Review of Biochemistry

Calcium-Dependent Lateral Organization in Phosphatidylinositol 4,5-Bisphosphate (PIP2)- and Cholesterol-Containing Monolayers

(2009) Ilya Levental et al.   BIOCHEMISTRY

Lipid Mixing and Content Release in Single-Vesicle, SNARE-Driven Fusion Assay with 1–5 ms Resolution

(2009) Tingting Wang et al.   BIOPHYSICAL JOURNAL

The Ca2+Affinity of Synaptotagmin 1 Is Markedly Increased by a Specific Interaction of Its C2B Domain with Phosphatidylinositol 4,5-Bisphosphate

(2009) Anand Radhakrishnan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synaptotagmin-1 functions as a Ca2+ sensor for spontaneous release

(2009) Jun Xu et al.   NATURE NEUROSCIENCE

Effects of linker sequences on vesicle fusion mediated by lipid-anchored DNA oligonucleotides

(2009) Y.-H. M. Chan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Discrimination between docking and fusion of liposomes reconstituted with neuronal SNARE-proteins using FCS

(2009) A. Cypionka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alternative Zippering as an On-Off Switch for SNARE-Mediated Fusion

(2009) C. G. Giraudo et al.   SCIENCE

Complexin Controls the Force Transfer from SNARE Complexes to Membranes in Fusion

(2009) A. Maximov et al.   SCIENCE

Advances in Single-Molecule Fluorescence Methods for Molecular Biology

(2008) Chirlmin Joo et al.   Annual Review of Biochemistry

Synaptic Vesicles Are Constitutively Active Fusion Machines that Function Independently of Ca 2+

(2008) Matthew Holt et al.   CURRENT BIOLOGY

Imaging the assembly and disassembly kinetics ofcis-SNARE complexes on native plasma membranes

(2008) Dana Bar-On et al.   FEBS LETTERS

Synaptotagmin arrests the SNARE complex before triggering fast, efficient membrane fusion in response to Ca2+

(2008) Michael C Chicka et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Single-particle kinetics of influenza virus membrane fusion

(2008) D. L. Floyd et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Video-Rate Far-Field Optical Nanoscopy Dissects Synaptic Vesicle Movement

(2008) V. Westphal et al.   SCIENCE

Conformational Switch of Syntaxin-1 Controls Synaptic Vesicle Fusion

(2008) Stefan H. Gerber et al.   SCIENCE

Accessory Proteins Stabilize the Acceptor Complex for Synaptobrevin, the 1:1 Syntaxin/SNAP-25 Complex

(2008) Keith Weninger et al.   STRUCTURE