Calmodulin-controlled spatial decoding of oscillatory Ca2+ signals by calcineurin

Calmodulin Transduces Ca2+ Oscillations into Differential Regulation of Its Target Proteins

(2013) Nikolai Slavov et al.   ACS Chemical Neuroscience

Modulation of ER stress and apoptosis by endoplasmic reticulum calcium leak via translocon during unfolded protein response: involvement of GRP78

(2013) Mehdi Hammadi et al.   FASEB JOURNAL

A Calcineurin Docking Motif (LXVP) in Dynamin-related Protein 1 Contributes to Mitochondrial Fragmentation and Ischemic Neuronal Injury

(2013) Andrew M. Slupe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insulin Secretion and Ca2+Dynamics in β-Cells Are Regulated by PERK (EIF2AK3) in Concert with Calcineurin

(2013) Rong Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Improved Targeted cAMP Sensor to Study the Regulation of Adenylyl Cyclase 8 by Ca2+ Entry through Voltage-Gated Channels

(2013) Katy L. Everett et al.   PLoS One

Nonlinear Decoding and Asymmetric Representation of Neuronal Input Information by CaMKIIα and Calcineurin

(2013) Hajime Fujii et al.   Cell Reports

Genetically encoded calcium indicators for multi-color neural activity imaging and combination with optogenetics

(2013) Jasper Akerboom et al.   Frontiers in Molecular Neuroscience

Anchored phosphatases modulate glucose homeostasis

(2012) Simon A Hinke et al.   EMBO JOURNAL

Distinct Dendritic Spine and Nuclear Phases of Calcineurin Activation after Exposure to Amyloid-  Revealed by a Novel Fluorescence Resonance Energy Transfer Assay

(2012) H.-Y. Wu et al.   JOURNAL OF NEUROSCIENCE

Endoplasmic reticulum–mitochondria contacts: function of the junction

(2012) Ashley A. Rowland et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Balanced interactions of calcineurin with AKAP79 regulate Ca2+–calcineurin–NFAT signaling

(2012) Huiming Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Calcium Input Frequency, Duration and Amplitude Differentially Modulate the Relative Activation of Calcineurin and CaMKII

(2012) Lu Li et al.   PLoS One

How cells process information: Quantification of spatiotemporal signaling dynamics

(2012) Ambhighainath Ganesan et al.   PROTEIN SCIENCE

Calcineurin Inhibition and New-Onset Diabetes Mellitus After Transplantation

(2012) Harini A. Chakkera et al.   TRANSPLANTATION

Reporting from the Field: Genetically Encoded Fluorescent Reporters Uncover Signaling Dynamics in Living Biological Systems

(2011) Sohum Mehta et al.   Annual Review of Biochemistry

A model for Ca2+ oscillations stimulated by the type 5 metabotropic glutamate receptor: An unusual mechanism based on repetitive, reversible phosphorylation of the receptor

(2011) Geneviève Dupont et al.   BIOCHIMIE

Cardiomyocyte calcineurin signaling in subcellular domains: From the sarcolemma to the nucleus and beyond

(2011) Joerg Heineke et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Calmodulin binding proteins provide domains of local Ca2+ signaling in cardiac myocytes

(2011) Jeffrey J. Saucerman et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Structural Basis for Activation of Calcineurin by Calmodulin

(2011) Julie Rumi-Masante et al.   JOURNAL OF MOLECULAR BIOLOGY

An Improved Cerulean Fluorescent Protein with Enhanced Brightness and Reduced Reversible Photoswitching

(2011) Michele L. Markwardt et al.   PLoS One

Architecture and dynamics of an A-kinase anchoring protein 79 (AKAP79) signaling complex

(2011) M. G. Gold et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ER Tubules Mark Sites of Mitochondrial Division

(2011) J. R. Friedman et al.   SCIENCE

Inhibition of Drp1-dependent mitochondrial fragmentation and apoptosis by a polypeptide antagonist of calcineurin

(2010) G M Cereghetti et al.   CELL DEATH AND DIFFERENTIATION

Oscillatory signaling processes: the how, the why and the where

(2010) Raymond Cheong et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

An intimate liaison: spatial organization of the endoplasmic reticulum–mitochondria relationship

(2010) Olga Martins de Brito et al.   EMBO JOURNAL

Visualization of PKA activity in plasma membrane microdomains

(2010) Charlene Depry et al.   Molecular BioSystems

Signaling diversity of PKA achieved via a Ca2+-cAMP-PKA oscillatory circuit

(2010) Qiang Ni et al.   Nature Chemical Biology

Spontaneous network activity visualized by ultrasensitive Ca2+ indicators, yellow Cameleon-Nano

(2010) Kazuki Horikawa et al.   NATURE METHODS

Transgenic Overexpression of Active Calcineurin in β-Cells Results in Decreased β-Cell Mass and Hyperglycemia

(2010) Ernesto Bernal-Mizrachi et al.   PLoS One

Calcineurin Interacts with PERK and Dephosphorylates Calnexin to Relieve ER Stress in Mammals and Frogs

(2010) Mariana Bollo et al.   PLoS One

Decoding cytosolic Ca2+ oscillations

(2010) Anant B. Parekh   TRENDS IN BIOCHEMICAL SCIENCES

Physical and Functional Interaction Between Calcineurin and the Cardiac L-Type Ca 2+ Channel

(2009) Samvit Tandan et al.   CIRCULATION RESEARCH

The A-kinase anchor protein AKAP121 is a negative regulator of cardiomyocyte hypertrophy

(2009) Bernard Abrenica et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators

(2009) Lin Tian et al.   NATURE METHODS

A Renewed Model of CNA Regulation Involving Its C-Terminal Regulatory Domain and CaM†

(2008) Hailong Wang et al.   BIOCHEMISTRY

Calmodulin Mediates Differential Sensitivity of CaMKII and Calcineurin to Local Ca2+ in Cardiac Myocytes

(2008) Jeffrey J. Saucerman et al.   BIOPHYSICAL JOURNAL

A Molecular Switch for Targeting between Endoplasmic Reticulum (ER) and Mitochondria

(2008) Yuliang Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential Integration of Ca2+-Calmodulin Signal in Intact Ventricular Myocytes at Low and High Affinity Ca2+-Calmodulin Targets

(2008) Qiujing Song et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oscillatory control of insulin secretion

(2008) A TENGHOLM et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Spatiotemporal Analysis of Differential Akt Regulation in Plasma Membrane Microdomains

(2008) Xinxin Gao et al.   MOLECULAR BIOLOGY OF THE CELL

Visualization of phosphatase activity in living cells with a FRET-based calcineurin activity sensor

(2008) Robert H. Newman et al.   Molecular BioSystems

Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria

(2008) G. M. Cereghetti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ca2+ oscillation frequency decoding in cardiac cell hypertrophy: Role of calcineurin/NFAT as Ca2+ signal integrators

(2008) M. Colella et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA