An Improved Targeted cAMP Sensor to Study the Regulation of Adenylyl Cyclase 8 by Ca2+ Entry through Voltage-Gated Channels

Extracellular calcium influx activates adenylate cyclase 1 and potentiates insulin secretion in MIN6 cells

(2013) Tetsuya Kitaguchi et al.   BIOCHEMICAL JOURNAL

cAMP measurements with FRET-based sensors in excitable cells

(2012) Katy L. Everett et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Direct Binding Between Orai1 and AC8 Mediates Dynamic Interplay Between Ca2+ and cAMP Signaling

(2012) D. Willoughby et al.   Science Signaling

An Ion-insensitive cAMP Biosensor for Long Term Quantitative Ratiometric Fluorescence Resonance Energy Transfer (FRET) Measurements under Variable Physiological Conditions

(2011) Petrus S. Salonikidis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A mTurquoise-Based cAMP Sensor for Both FLIM and Ratiometric Read-Out Has Improved Dynamic Range

(2011) Jeffrey B. Klarenbeek et al.   PLoS One

Adenylyl cyclase 8 is central to glucagon-like peptide 1 signalling and effects of chronically elevated glucose in rat and human pancreatic beta cells

(2010) B. Roger et al.   DIABETOLOGIA

Sub-picomolar relaxin signalling by a pre-assembled RXFP1, AKAP79, AC2, β-arrestin 2, PDE4D3 complex

(2010) Michelle L Halls et al.   EMBO JOURNAL

cAMP Mediators of Pulsatile Insulin Secretion from Glucose-stimulated Single β-Cells

(2010) Olof Idevall-Hagren et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AKAP79/150 Interacts with AC8 and Regulates Ca2+-dependent cAMP Synthesis in Pancreatic and Neuronal Systems

(2010) Debbie Willoughby et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AKAP79 Interacts with Multiple Adenylyl Cyclase (AC) Isoforms and Scaffolds AC5 and -6 to α-Amino-3-hydroxyl-5-methyl-4-isoxazole-propionate (AMPA) Receptors

(2010) Riad Efendiev et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bright cyan fluorescent protein variants identified by fluorescence lifetime screening

(2010) Joachim Goedhart et al.   NATURE METHODS

The Calcium Store Sensor, STIM1, Reciprocally Controls Orai and CaV1.2 Channels

(2010) Y. Wang et al.   SCIENCE

Distinct pools of cAMP centre on different isoforms of adenylyl cyclase in pituitary-derived GH3B6 cells

(2009) S. Wachten et al.   JOURNAL OF CELL SCIENCE

Direct demonstration of discrete Ca2+ microdomains associated with different isoforms of adenylyl cyclase

(2009) D. Willoughby et al.   JOURNAL OF CELL SCIENCE

The Intracellular II-III Loops of Cav1.2 and Cav1.3 Uncouple L-Type Voltage-Gated Ca2+ Channels from Glucagon-Like Peptide-1 Potentiation of Insulin Secretion in INS-1 Cells via Displacement from Lipid Rafts

(2009) S. M. P. Jacobo et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The role of membrane microdomains in shaping β2-adrenergic receptor-mediated cAMP dynamics

(2009) Lisa M. DiPilato et al.   Molecular BioSystems

Capacitative Ca2+ Entry via Orai1 and Stromal Interacting Molecule 1 (STIM1) Regulates Adenylyl Cyclase Type 8

(2009) A. C. L. Martin et al.   MOLECULAR PHARMACOLOGY

Glucose-Induced Cyclic AMP Oscillations Regulate Pulsatile Insulin Secretion

(2008) Oleg Dyachok et al.   Cell Metabolism

Oscillatory control of insulin secretion

(2008) A TENGHOLM et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

A modular switch for spatial Ca2+ selectivity in the calmodulin regulation of CaV channels

(2008) Ivy E. Dick et al.   NATURE

A genetically encoded fluorescent sensor of ERK activity

(2008) C. D. Harvey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epac-selective cAMP analogs: New tools with which to evaluate the signal transduction properties of cAMP-regulated guanine nucleotide exchange factors

(2007) George G. Holz et al.   CELLULAR SIGNALLING