Antagonizing Interferon-Mediated Immune Response by Porcine Reproductive and Respiratory Syndrome Virus

Targeted mutations in a highly conserved motif of the nsp1  protein impair the interferon antagonizing activity of porcine reproductive and respiratory syndrome virus

(2013) Y. Li et al.   JOURNAL OF GENERAL VIROLOGY

Arterivirus molecular biology and pathogenesis

(2013) E. J. Snijder et al.   JOURNAL OF GENERAL VIROLOGY

Porcine Reproductive and Respiratory Syndrome Virus Nsp1  Inhibits Interferon-Activated JAK/STAT Signal Transduction by Inducing Karyopherin- 1 Degradation

(2013) R. Wang et al.   JOURNAL OF VIROLOGY

Enhancing neutralizing antibody production by an interferon-inducing porcine reproductive and respiratory syndrome virus strain

(2013) Rong Wang et al.   VACCINE

Variable interference with interferon signal transduction by different strains of porcine reproductive and respiratory syndrome virus

(2013) Rong Wang et al.   VETERINARY MICROBIOLOGY

Amino acid at position 176 was essential for porcine reproductive and respiratory syndrome virus (PRRSV) non-structural protein 1α (nsp1α) as an inhibitor to the induction of IFN-β

(2012) Xibao Shi et al.   CELLULAR IMMUNOLOGY

Nonstructural Protein 2 of Porcine Reproductive and Respiratory Syndrome Virus Inhibits the Antiviral Function of Interferon-Stimulated Gene 15

(2012) Z. Sun et al.   JOURNAL OF VIROLOGY

Porcine reproductive and respiratory syndrome virus activates the transcription of interferon alpha/beta (IFN-α/β) in monocyte-derived dendritic cells (Mo-DC)

(2012) Hanmo Zhang et al.   VETERINARY MICROBIOLOGY

Induction of type I interferons by a novel porcine reproductive and respiratory syndrome virus isolate

(2012) Yuchen Nan et al.   VIROLOGY

Experimental infection of United States swine with a Chinese highly pathogenic strain of porcine reproductive and respiratory syndrome virus

(2012) Baoqing Guo et al.   VIROLOGY

Interplay between Interferon-Mediated Innate Immunity and Porcine Reproductive and Respiratory Syndrome Virus

(2012) Yan Sun et al.   Viruses-Basel

Porcine reproductive and respiratory syndrome virus nucleocapsid protein modulates interferon-β production by inhibiting IRF3 activation in immortalized porcine alveolar macrophages

(2011) Mingeun Sagong et al.   ARCHIVES OF VIROLOGY

Endoribonuclease activities of porcine reproductive and respiratory syndrome virus nsp11 was essential for nsp11 to inhibit IFN-β induction

(2011) Xibao Shi et al.   MOLECULAR IMMUNOLOGY

Interaction between innate immunity and porcine reproductive and respiratory syndrome virus

(2011) Yongming Sang et al.   ANIMAL HEALTH RESEARCH REVIEWS

The cysteine protease domain of porcine reproductive and respiratory syndrome virus non-structural protein 2 antagonizes interferon regulatory factor 3 activation

(2010) H. Li et al.   JOURNAL OF GENERAL VIROLOGY

Porcine Reproductive and Respiratory Syndrome Virus Inhibits Type I Interferon Signaling by Blocking STAT1/STAT2 Nuclear Translocation

(2010) D. Patel et al.   JOURNAL OF VIROLOGY

North American Porcine Reproductive and Respiratory Syndrome Viruses Inhibit Type I Interferon Production by Plasmacytoid Dendritic Cells

(2010) G. Calzada-Nova et al.   JOURNAL OF VIROLOGY

The Cysteine Protease Domain of Porcine Reproductive and Respiratory Syndrome Virus Nonstructural Protein 2 Possesses Deubiquitinating and Interferon Antagonism Functions

(2010) Z. Sun et al.   JOURNAL OF VIROLOGY

Differential expression and activity of the porcine type I interferon family

(2010) Yongming Sang et al.   PHYSIOLOGICAL GENOMICS

Marked differences between MARC-145 cells and swine alveolar macrophages in IFNβ-induced activation of antiviral state against PRRSV

(2010) D. He et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Modulation of type I interferon induction by porcine reproductive and respiratory syndrome virus and degradation of CREB-binding protein by non-structural protein 1 in MARC-145 and HeLa cells

(2010) Oekyung Kim et al.   VIROLOGY

Nonstructural protein 1α subunit-based inhibition of NF-κB activation and suppression of interferon-β production by porcine reproductive and respiratory syndrome virus

(2010) Cheng Song et al.   VIROLOGY

Porcine reproductive and respiratory syndrome virus (PRRSV) could be sensed by professional beta interferon-producing system and had mechanisms to inhibit this action in MARC-145 cells

(2010) Xibao Shi et al.   VIRUS RESEARCH

Modulation of host cell responses and evasion strategies for porcine reproductive and respiratory syndrome virus

(2010) Dongwan Yoo et al.   VIRUS RESEARCH

Interferons and viral infections

(2009) Volker Fensterl et al.   BIOFACTORS

Structure and Cleavage Specificity of the Chymotrypsin-Like Serine Protease (3CLSP/nsp4) of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV)

(2009) Xinsheng Tian et al.   JOURNAL OF MOLECULAR BIOLOGY

Biochemical Characterization of Arterivirus Nonstructural Protein 11 Reveals the Nidovirus-Wide Conservation of a Replicative Endoribonuclease

(2009) D. D. Nedialkova et al.   JOURNAL OF VIROLOGY

Porcine Reproductive and Respiratory Syndrome Virus Nonstructural Protein 1  Modulates Host Innate Immune Response by Antagonizing IRF3 Activation

(2009) L. K. Beura et al.   JOURNAL OF VIROLOGY

Characterization of the cytokine and maturation responses of pure populations of porcine plasmacytoid dendritic cells to porcine viruses and toll-like receptor agonists

(2009) Gabriela Calzada-Nova et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Adenovirus-Mediated Expression of Interferon-α Delays Viral Replication and Reduces Disease Signs in Swine Challenged with Porcine Reproductive and Respiratory Syndrome Virus

(2009) S.L. Brockmeier et al.   VIRAL IMMUNOLOGY

Identification of two auto-cleavage products of nonstructural protein 1 (nsp1) in porcine reproductive and respiratory syndrome virus infected cells: nsp1 function as interferon antagonist

(2009) Z. Chen et al.   VIROLOGY

Porcine reproductive and respiratory syndrome virus (PRRSV) suppresses interferon-β production by interfering with the RIG-I signaling pathway

(2008) Rui Luo et al.   MOLECULAR IMMUNOLOGY