Targeted mutations in a highly conserved motif of the nsp1  protein impair the interferon antagonizing activity of porcine reproductive and respiratory syndrome virus

Identification of porcine reproductive and respiratory syndrome virus ORF1a-encoded non-structural proteins in virus-infected cells

(2012) Y. Li et al.   JOURNAL OF GENERAL VIROLOGY

Nonstructural Protein 2 of Porcine Reproductive and Respiratory Syndrome Virus Inhibits the Antiviral Function of Interferon-Stimulated Gene 15

(2012) Z. Sun et al.   JOURNAL OF VIROLOGY

Severe Acute Respiratory Syndrome Coronavirus Protein nsp1 Is a Novel Eukaryotic Translation Inhibitor That Represses Multiple Steps of Translation Initiation

(2012) K. G. Lokugamage et al.   JOURNAL OF VIROLOGY

Efficient -2 frameshifting by mammalian ribosomes to synthesize an additional arterivirus protein

(2012) Y. Fang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SARS Coronavirus nsp1 Protein Induces Template-Dependent Endonucleolytic Cleavage of mRNAs: Viral mRNAs Are Resistant to nsp1-Induced RNA Cleavage

(2011) Cheng Huang et al.   PLoS Pathogens

Porcine Reproductive and Respiratory Syndrome Virus Inhibits Type I Interferon Signaling by Blocking STAT1/STAT2 Nuclear Translocation

(2010) D. Patel et al.   JOURNAL OF VIROLOGY

The Crystal Structure of Porcine Reproductive and Respiratory Syndrome Virus Nonstructural Protein Nsp1  Reveals a Novel Metal-Dependent Nuclease

(2010) F. Xue et al.   JOURNAL OF VIROLOGY

Development of an 8-plex Luminex assay to detect swine cytokines for vaccine development: Assessment of immunity after porcine reproductive and respiratory syndrome virus (PRRSV) vaccination

(2010) Steven Lawson et al.   VACCINE

Modulation of type I interferon induction by porcine reproductive and respiratory syndrome virus and degradation of CREB-binding protein by non-structural protein 1 in MARC-145 and HeLa cells

(2010) Oekyung Kim et al.   VIROLOGY

Nonstructural protein 1α subunit-based inhibition of NF-κB activation and suppression of interferon-β production by porcine reproductive and respiratory syndrome virus

(2010) Cheng Song et al.   VIROLOGY

The PRRSV replicase: Exploring the multifunctionality of an intriguing set of nonstructural proteins

(2010) Ying Fang et al.   VIRUS RESEARCH

Modulation of host cell responses and evasion strategies for porcine reproductive and respiratory syndrome virus

(2010) Dongwan Yoo et al.   VIRUS RESEARCH

Porcine Reproductive and Respiratory Syndrome Virus Nonstructural Protein 1  Modulates Host Innate Immune Response by Antagonizing IRF3 Activation

(2009) L. K. Beura et al.   JOURNAL OF VIROLOGY

A two-pronged strategy to suppress host protein synthesis by SARS coronavirus Nsp1 protein

(2009) Wataru Kamitani et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Identification of two auto-cleavage products of nonstructural protein 1 (nsp1) in porcine reproductive and respiratory syndrome virus infected cells: nsp1 function as interferon antagonist

(2009) Z. Chen et al.   VIROLOGY

Severe Acute Respiratory Syndrome Coronavirus nsp1 Suppresses Host Gene Expression, Including That of Type I Interferon, in Infected Cells

(2008) K. Narayanan et al.   JOURNAL OF VIROLOGY