Nonstructural Protein 2 of Porcine Reproductive and Respiratory Syndrome Virus Inhibits the Antiviral Function of Interferon-Stimulated Gene 15

Discovery of a small arterivirus gene that overlaps the GP5 coding sequence and is important for virus production

(2011) A. E. Firth et al.   JOURNAL OF GENERAL VIROLOGY

Novel structural protein in porcine reproductive and respiratory syndrome virus encoded by an alternative ORF5 present in all arteriviruses

(2011) C. R. Johnson et al.   JOURNAL OF GENERAL VIROLOGY

Arterivirus and Nairovirus Ovarian Tumor Domain-Containing Deubiquitinases Target Activated RIG-I To Control Innate Immune Signaling

(2011) P. B. van Kasteren et al.   JOURNAL OF VIROLOGY

Molecular basis for ubiquitin and ISG15 cross-reactivity in viral ovarian tumor domains

(2011) M. Akutsu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for the removal of ubiquitin and interferon-stimulated gene 15 by a viral ovarian tumor domain-containing protease

(2011) T. W. James et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Emerging Role of ISG15 in Antiviral Immunity

(2010) Brian Skaug et al.   CELL

Inhibition of Hepatitis C Virus Replication by IFN-Mediated ISGylation of HCV-NS5A

(2010) M.-J. Kim et al.   JOURNAL OF IMMUNOLOGY

Interferon-Stimulated Gene 15 and the Protein ISGylation System

(2010) Dongxian Zhang et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Deubiquitinating and Interferon Antagonism Activities of Coronavirus Papain-Like Proteases

(2010) M. A. Clementz et al.   JOURNAL OF VIROLOGY

The Cysteine Protease Domain of Porcine Reproductive and Respiratory Syndrome Virus Nonstructural Protein 2 Possesses Deubiquitinating and Interferon Antagonism Functions

(2010) Z. Sun et al.   JOURNAL OF VIROLOGY

The ISG15 Conjugation System Broadly Targets Newly Synthesized Proteins: Implications for the Antiviral Function of ISG15

(2010) Larissa A. Durfee et al.   MOLECULAR CELL

The PRRSV replicase: Exploring the multifunctionality of an intriguing set of nonstructural proteins

(2010) Ying Fang et al.   VIRUS RESEARCH

ISG15 over-expression inhibits replication of the Japanese encephalitis virus in human medulloblastoma cells

(2009) Nai-Wan Hsiao et al.   ANTIVIRAL RESEARCH

Influenza B mutant viruses with truncated NS1 proteins grow efficiently in Vero cells and are immunogenic in mice

(2009) N. Wressnigg et al.   JOURNAL OF GENERAL VIROLOGY

Immunodominant epitopes in nsp2 of porcine reproductive and respiratory syndrome virus are dispensable for replication, but play an important role in modulation of the host immune response

(2009) Z. Chen et al.   JOURNAL OF GENERAL VIROLOGY

The Porcine Reproductive and Respiratory Syndrome Virus nsp2 Cysteine Protease Domain Possesses both trans- and cis-Cleavage Activities

(2009) J. Han et al.   JOURNAL OF VIROLOGY

Porcine Reproductive and Respiratory Syndrome Virus Nonstructural Protein 1  Modulates Host Innate Immune Response by Antagonizing IRF3 Activation

(2009) L. K. Beura et al.   JOURNAL OF VIROLOGY

Identification of two auto-cleavage products of nonstructural protein 1 (nsp1) in porcine reproductive and respiratory syndrome virus infected cells: nsp1 function as interferon antagonist

(2009) Z. Chen et al.   VIROLOGY

The nsp1  and nsp1 papain-like autoproteinases are essential for porcine reproductive and respiratory syndrome virus RNA synthesis

(2008) M. V. Kroese et al.   JOURNAL OF GENERAL VIROLOGY

Live Attenuated Influenza Viruses Containing NS1 Truncations as Vaccine Candidates against H5N1 Highly Pathogenic Avian Influenza

(2008) J. Steel et al.   JOURNAL OF VIROLOGY

ISG15 inhibits Ebola VP40 VLP budding in an L-domain-dependent manner by blocking Nedd4 ligase activity

(2008) A. Okumura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vaccinia Virus E3 Protein Prevents the Antiviral Action of ISG15

(2008) Susana Guerra et al.   PLoS Pathogens

Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures

(2007) R. E. Randall et al.   JOURNAL OF GENERAL VIROLOGY