The Endothelial ADMA/NO Pathway in Hypoxia-Related Chronic Respiratory Diseases

Effects of Dimethylarginine Dimethylaminohydrolase–1 Overexpression on the Response of the Pulmonary Vasculature to Hypoxia

(2013) Adel Bakr et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Symmetrical Dimethylarginine Predicts Mortality in the General Population

(2013) M. Odette Gore et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Regulation of erythropoiesis by hypoxia-inducible factors

(2013) Volker H. Haase   BLOOD REVIEWS

The yin and yang of nitric oxide in cancer progression

(2013) A. J. Burke et al.   CARCINOGENESIS

Riociguat for the Treatment of Pulmonary Arterial Hypertension

(2013) Hossein-Ardeschir Ghofrani et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Relationship between Lung Inflammation and Cardiovascular Disease

(2012) Stephan Van Eeden et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Online trapping and enrichment ultra performance liquid chromatography–tandem mass spectrometry method for sensitive measurement of “arginine-asymmetric dimethylarginine cycle” biomarkers in human exhaled breath condensate

(2012) Iole Maria Di Gangi et al.   ANALYTICA CHIMICA ACTA

Genetic and Pharmacological Inhibition of Dimethylarginine Dimethylaminohydrolase 1 Is Protective in Endotoxic Shock

(2012) Manasi Nandi et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Hypoxia-Inducible Factors in Physiology and Medicine

(2012) Gregg L. Semenza   CELL

NOS2 enhances KRAS-induced lung carcinogenesis, inflammation and microRNA-21 expression

(2012) Hirokazu Okayama et al.   INTERNATIONAL JOURNAL OF CANCER

Molecular pathogenesis of pulmonary arterial hypertension

(2012) Marlene Rabinovitch   JOURNAL OF CLINICAL INVESTIGATION

The role of hypoxia-inducible factor 1 in atherosclerosis: Figure 1

(2012) Linggen Gao et al.   JOURNAL OF CLINICAL PATHOLOGY

Interaction of the cardiovascular risk marker asymmetric dimethylarginine (ADMA) with the human cationic amino acid transporter 1 (CAT1)

(2012) Joachim Strobel et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Nitric oxide signaling in hypoxia

(2012) J. J. David Ho et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

The role of dimethylarginine dimethylaminohydrolase (DDAH) in pulmonary fibrosis

(2012) Wiebke Janssen et al.   JOURNAL OF PATHOLOGY

Asymmetric Dimethylarginine Is Increased in Asthma

(2011) Jeremy A. Scott et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Dysregulation of the HIF pathway due to VHL mutation causing severe erythrocytosis and pulmonary arterial hypertension

(2011) J. Bond et al.   BLOOD

Inducible NOS Inhibition Reverses Tobacco-Smoke-Induced Emphysema and Pulmonary Hypertension in Mice

(2011) Michael Seimetz et al.   CELL

cAMP Phosphodiesterase Inhibitors Increases Nitric Oxide Production by Modulating Dimethylarginine Dimethylaminohydrolases

(2011) Soni Savai Pullamsetti et al.   CIRCULATION

Symmetric dimethylarginine is a marker of detrimental outcome in the acute phase after ischaemic stroke: role of renal function

(2011) Nicole Lüneburg et al.   CLINICAL SCIENCE

Chronic lung allograft rejection and airway microvasculature: Is HIF-1 the missing link?

(2011) David S. Wilkes   JOURNAL OF CLINICAL INVESTIGATION

Studies on the Reaction of Nitric Oxide with the Hypoxia-Inducible Factor Prolyl Hydroxylase Domain 2 (EGLN1)

(2011) Rasheduzzaman Chowdhury et al.   JOURNAL OF MOLECULAR BIOLOGY

Idiopathic pulmonary fibrosis

(2011) Talmadge E King et al.   LANCET

The role of asymmetric and symmetric dimethylarginines in renal disease

(2011) Edzard Schwedhelm et al.   Nature Reviews Nephrology

Oxygen Sensing, Homeostasis, and Disease

(2011) Gregg L. Semenza   NEW ENGLAND JOURNAL OF MEDICINE

The Role of Dimethylarginine Dimethylaminohydrolase in Idiopathic Pulmonary Fibrosis

(2011) S. S. Pullamsetti et al.   Science Translational Medicine

Asymmetric dimethylarginine potentiates lung inflammation in a mouse model of allergic asthma

(2010) Elizabeth Klein et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Pulmonary Hypertension in COPD: Epidemiology, Significance, and Management

(2010) Omar A. Minai et al.   CHEST

Review article: Asymmetric dimethylarginine as a mediator of vascular dysfunction and a marker of cardiovascular disease and mortality: an intriguing interaction with diabetes mellitus

(2010) Maike Anderssohn et al.   Diabetes & Vascular Disease Research

Riociguat for chronic thromboembolic pulmonary hypertension and pulmonary arterial hypertension: a phase II study

(2010) H. A. Ghofrani et al.   EUROPEAN RESPIRATORY JOURNAL

Tumor necrosis is a new promising prognostic factor in colorectal cancer

(2010) Marion J. Pollheimer et al.   HUMAN PATHOLOGY

Dysregulation of PRMT1 and PRMT6, Type I arginine methyltransferases, is involved in various types of human cancers

(2010) Masanori Yoshimatsu et al.   INTERNATIONAL JOURNAL OF CANCER

Asymmetric dimethylarginine as an independent risk marker for mortality in ambulatory patients with peripheral arterial disease

(2010) R. H. Böger et al.   JOURNAL OF INTERNAL MEDICINE

Regulation of the ADMA-DDAH system in endothelial cells: a novel mechanism for the sterol response element binding proteins, SREBP1c and -2

(2009) Christine Y. Ivashchenko et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

l-Arginine promotes angiogenesis in the chronically hypoxic lung: a novel mechanism ameliorating pulmonary hypertension

(2009) K. Howell et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Altered Asymmetric Dimethyl Arginine Metabolism in Allergically Inflamed Mouse Lungs

(2009) Tanveer Ahmad et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Symmetric dimethylarginine predicts all-cause mortality following ischemic stroke

(2009) Friedrich Schulze et al.   ATHEROSCLEROSIS

Regenerative Therapy in Peripheral Artery Disease

(2009) Antonia Germani et al.   Cardiovascular Therapeutics

Forskolin increases angiogenesis through the coordinated cross-talk of PKA-dependent VEGF expression and Epac-mediated PI3K/Akt/eNOS signaling

(2009) Seung Namkoong et al.   CELLULAR SIGNALLING

Vascular Endothelial-Specific Dimethylarginine Dimethylaminohydrolase-1–Deficient Mice Reveal That Vascular Endothelium Plays an Important Role in Removing Asymmetric Dimethylarginine

(2009) Xinli Hu et al.   CIRCULATION

Cardiovascular disease in obstructive sleep apnoea syndrome: the role of intermittent hypoxia and inflammation

(2009) J. F. Garvey et al.   EUROPEAN RESPIRATORY JOURNAL

L-Arginine deficiency causes airway hyperresponsiveness after the late asthmatic reaction

(2009) H. Maarsingh et al.   EUROPEAN RESPIRATORY JOURNAL

The Role of Nitric Oxide Synthase Inhibition by Asymmetric Dimethylarginine in the Pathophysiology of Preeclampsia

(2009) Rainer H. Böger et al.   GYNECOLOGIC AND OBSTETRIC INVESTIGATION

Asymmetric dimethylarginine (ADMA) as a prospective marker of cardiovascular disease and mortality—An update on patient populations with a wide range of cardiovascular risk

(2009) Rainer H. Böger et al.   PHARMACOLOGICAL RESEARCH

From arginine methylation to ADMA: A novel mechanism with therapeutic potential in chronic lung diseases

(2009) Dariusz Zakrzewicz et al.   BMC Pulmonary Medicine

Alterations of the Arginine Metabolome in Asthma

(2008) Abigail Lara et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Asymmetric and symmetric dimethylarginines are of similar predictive value for cardiovascular risk in the general population

(2008) Stefan Kiechl et al.   ATHEROSCLEROSIS

Regulation of eNOS-Derived Superoxide by Endogenous Methylarginines†

(2008) Lawrence J. Druhan et al.   BIOCHEMISTRY

Regulation of hypoxic pulmonary vasoconstriction: basic mechanisms

(2008) N. Sommer et al.   EUROPEAN RESPIRATORY JOURNAL

Phosphodiesterase inhibitors for the treatment of pulmonary hypertension

(2008) M. R. Wilkins et al.   EUROPEAN RESPIRATORY JOURNAL

Changes in elastic fibres in the small airways and alveoli in COPD

(2008) P. N. Black et al.   EUROPEAN RESPIRATORY JOURNAL

Intermittent hypoxia and sleep-disordered breathing: current concepts and perspectives

(2008) P. Levy et al.   EUROPEAN RESPIRATORY JOURNAL

Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway

(2008) William G. Kaelin et al.   MOLECULAR CELL

Cardiovascular Morbidity in Obstructive Sleep Apnea

(2007) David Gozal et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Mucosal Protection by Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibition

(2007) Andreas Robinson et al.   GASTROENTEROLOGY