Molecular Mechanisms Underlying the Role of MicroRNAs in the Chemoresistance of Pancreatic Cancer
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Molecular Mechanisms Underlying the Role of MicroRNAs in the Chemoresistance of Pancreatic Cancer
Authors
Keywords
-
Journal
Biomed Research International
Volume 2014, Issue -, Pages 1-17
Publisher
Hindawi Limited
Online
2014-08-29
DOI
10.1155/2014/678401
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The TGF -miR200-MIG6 Pathway Orchestrates the EMT-Associated Kinase Switch That Induces Resistance to EGFR Inhibitors
- (2014) E. Izumchenko et al. CANCER RESEARCH
- HER2 aberrations in cancer: Implications for therapy
- (2014) Min Yan et al. CANCER TREATMENT REVIEWS
- MicroRNAs in personalized cancer therapy
- (2014) S. Sethi et al. CLINICAL GENETICS
- A microRNA meta-signature for pancreatic ductal adenocarcinoma
- (2014) Adam E Frampton et al. EXPERT REVIEW OF MOLECULAR DIAGNOSTICS
- MicroRNA expression signatures for the prediction of BRCA1/2 mutation-associated hereditary breast cancer in paraffin-embedded formalin-fixed breast tumors
- (2014) Miljana Tanic et al. INTERNATIONAL JOURNAL OF CANCER
- miRNAs for the Detection of MultiDrug Resistance: Overview and Perspectives
- (2014) Andreas Gisel et al. MOLECULES
- Differentially Expressed miRNAs in Cancer-Stem-Like Cells: Markers for Tumor Cell Aggressiveness of Pancreatic Cancer
- (2014) Bin Bao et al. STEM CELLS AND DEVELOPMENT
- Circulating miR-210 as a Novel Hypoxia Marker in Pancreatic Cancer
- (2014) Allen S. Ho et al. Translational Oncology
- Role of pancreatic stellate cells in chemoresistance in pancreatic cancer
- (2014) Joshua A. McCarroll et al. Frontiers in Physiology
- Multicenter phase II trial to investigate safety and efficacy of gemcitabine combined with cetuximab as adjuvant therapy in pancreatic cancer (ATIP)
- (2013) H. Fensterer et al. ANNALS OF ONCOLOGY
- miR-210 regulates the interaction between pancreatic cancer cells and stellate cells
- (2013) Tetsuya Takikawa et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Stromal disrupting effects of nab-paclitaxel in pancreatic cancer
- (2013) R Alvarez et al. BRITISH JOURNAL OF CANCER
- Clinical impact of circulating miR-221 in plasma of patients with pancreatic cancer
- (2013) T Kawaguchi et al. BRITISH JOURNAL OF CANCER
- miR-320c regulates gemcitabine-resistance in pancreatic cancer via SMARCC1
- (2013) Y Iwagami et al. BRITISH JOURNAL OF CANCER
- Aberrant MicroRNAs Expression Patterns in Pancreatic Cancer and Their Clinical Translation
- (2013) Yiqi Du et al. CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS
- Targeting microRNAs in Pancreatic Cancer: Microplayers in the Big Game
- (2013) S. Khan et al. CANCER RESEARCH
- miRNA in clinical practice: Pancreatic cancer
- (2013) Marine Humeau et al. CLINICAL BIOCHEMISTRY
- miRNAs in Insulin Resistance and Diabetes-Associated Pancreatic Cancer: The ‘Minute and Miracle’ Molecule Moving as a Monitor in the ‘Genomic Galaxy’
- (2013) Chiranjib Chakraborty et al. CURRENT DRUG TARGETS
- MicroRNAs as therapeutic targets in chemoresistance
- (2013) Michela Garofalo et al. DRUG RESISTANCE UPDATES
- MicroRNAs Cooperatively Inhibit a Network of Tumor Suppressor Genes to Promote Pancreatic Tumor Growth and Progression
- (2013) Adam E. Frampton et al. GASTROENTEROLOGY
- The HER2-miR125a5p/miR125b loop in gastric and esophageal carcinogenesis
- (2013) Matteo Fassan et al. HUMAN PATHOLOGY
- An Undesired Effect of Chemotherapy
- (2013) Sumit Arora et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Candidate microRNA biomarkers of pancreatic ductal adenocarcinoma: meta-analysis, experimental validation and clinical significance
- (2013) Ming-Zhe Ma et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Hypoxia induces the overexpression of microRNA-21 in pancreatic cancer cells
- (2013) Thomas A. Mace et al. JOURNAL OF SURGICAL RESEARCH
- MicroRNAs and other non-coding RNAs as targets for anticancer drug development
- (2013) Hui Ling et al. NATURE REVIEWS DRUG DISCOVERY
- Long non-coding RNA identification over mouse brain development by integrative modeling of chromatin and genomic features
- (2013) Jie Lv et al. NUCLEIC ACIDS RESEARCH
- Macrophages mediate gemcitabine resistance of pancreatic adenocarcinoma by upregulating cytidine deaminase
- (2013) N Weizman et al. ONCOGENE
- Sweating the Small Stuff
- (2013) Siuwah Tang et al. PANCREAS
- Toward a Better Understanding of Pancreatic Ductal Adenocarcinoma
- (2013) Christian Partensky PANCREAS
- Pancreatic Cancer
- (2013) Emil Lou et al. PANCREAS
- Differential Processing of let-7a Precursors Influences RRM2 Expression and Chemosensitivity in Pancreatic Cancer: Role of LIN-28 and SET Oncoprotein
- (2013) Yangzom Doma Bhutia et al. PLoS One
- MicroRNA-mediated control of macrophages and its implications for cancer
- (2013) Mario Leonardo Squadrito et al. TRENDS IN IMMUNOLOGY
- MiR-148a regulates the growth and apoptosis in pancreatic cancer by targeting CCKBR and Bcl-2
- (2013) Rui Zhang et al. TUMOR BIOLOGY
- Clinical and molecular characterization of HER2 amplified-pancreatic cancer
- (2013) Angela Chou et al. Genome Medicine
- MicroRNAs in Kidney Fibrosis and Diabetic Nephropathy: Roles on EMT and EndMT
- (2013) Swayam Prakash Srivastava et al. Biomed Research International
- MicroRNA-gene signaling pathways in pancreatic cancer
- (2013) Dimitrios Iliopoulos et al. Biomedical Journal
- The good, the bad and the ugly: a tale of miR-101, miR-21 and miR-155 in pancreatic intraductal papillary mucinous neoplasms
- (2012) S. Caponi et al. ANNALS OF ONCOLOGY
- Pancreatic adenocarcinoma: ESMO-ESDO Clinical Practice Guidelines for diagnosis, treatment and follow-up
- (2012) T. Seufferlein et al. ANNALS OF ONCOLOGY
- MicroRNA-10a is Overexpressed in Human Pancreatic Cancer and Involved in Its Invasiveness Partially via Suppression of the HOXA1 Gene
- (2012) Kenoki Ohuchida et al. ANNALS OF SURGICAL ONCOLOGY
- MicroRNA-214 Regulates the Acquired Resistance to Gefitinib via the PTEN/AKT Pathway in EGFR-mutant Cell Lines
- (2012) Yong-Sheng Wang et al. Asian Pacific Journal of Cancer Prevention
- Multicentre phase II trial of trastuzumab and capecitabine in patients with HER2 overexpressing metastatic pancreatic cancer
- (2012) J Harder et al. BRITISH JOURNAL OF CANCER
- MicroRNAs in Stress Signaling and Human Disease
- (2012) Joshua T. Mendell et al. CELL
- The Pancreas Cancer Microenvironment
- (2012) C. Feig et al. CLINICAL CANCER RESEARCH
- Advances in Biomarker Research for Pancreatic Cancer
- (2012) Kruttika Bhat et al. CURRENT PHARMACEUTICAL DESIGN
- miR-17-5p Inhibitor Enhances Chemosensitivity to Gemcitabine Via Upregulating Bim Expression in Pancreatic Cancer Cells
- (2012) Hai-jiao Yan et al. DIGESTIVE DISEASES AND SCIENCES
- Treatment options for advanced pancreatic cancer: a review
- (2012) Rahma Warsame et al. Expert Review of Anticancer Therapy
- Landscape of transcription in human cells
- (2012) Sarah Djebali et al. NATURE
- New biomarkers and targets in pancreatic cancer and their application to treatment
- (2012) Eithne Costello et al. Nature Reviews Gastroenterology & Hepatology
- Long non-coding RNAs and cancer: a new frontier of translational research?
- (2012) R Spizzo et al. ONCOGENE
- Expression of MicroRNAs in Patients With Pancreatic Cancer and Its Prognostic Significance
- (2012) Ioannis G. Papaconstantinou et al. PANCREAS
- MicroRNAs Targeting Oncogenes Are Down-Regulated in Pancreatic Malignant Transformation from Benign Tumors
- (2012) Long R. Jiao et al. PLoS One
- Hypoxia-Induced Aggressiveness of Pancreatic Cancer Cells Is Due to Increased Expression of VEGF, IL-6 and miR-21, Which Can Be Attenuated by CDF Treatment
- (2012) Bin Bao et al. PLoS One
- High-Throughput MicroRNA (miRNAs) Arrays Unravel the Prognostic Role of MiR-211 in Pancreatic Cancer
- (2012) Elisa Giovannetti et al. PLoS One
- Causes, consequences, and remedies for growth-induced solid stress in murine and human tumors
- (2012) T. Stylianopoulos et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- nab -Paclitaxel Potentiates Gemcitabine Activity by Reducing Cytidine Deaminase Levels in a Mouse Model of Pancreatic Cancer
- (2012) Kristopher K. Frese et al. Cancer Discovery
- The role of inflammatory cells in fostering pancreatic cancer cell growth and invasion
- (2012) Eithne Costello Frontiers in Physiology
- MicroRNA Expression as a Predictive Marker for Gemcitabine Response after Surgical Resection of Pancreatic Cancer
- (2011) Kenoki Ohuchida et al. ANNALS OF SURGICAL ONCOLOGY
- Neoadjuvant/Preoperative Gemcitabine for Patients with Localized Pancreatic Cancer: A Meta-analysis of Prospective Studies
- (2011) Angelo Andriulli et al. ANNALS OF SURGICAL ONCOLOGY
- Bcl-2 Upregulation Induced by miR-21 Via a Direct Interaction Is Associated with Apoptosis and Chemoresistance in MIA PaCa-2 Pancreatic Cancer Cells
- (2011) Jie Dong et al. ARCHIVES OF MEDICAL RESEARCH
- MicroRNA 421 suppresses DPC4/Smad4 in pancreatic cancer
- (2011) Jun Hao et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- A microRNA gene expression signature predicts response to erlotinib in epithelial cancer cell lines and targets EMT
- (2011) J L Bryant et al. BRITISH JOURNAL OF CANCER
- MicroRNA-10b Expression Correlates with Response to Neoadjuvant Therapy and Survival in Pancreatic Ductal Adenocarcinoma
- (2011) M. Preis et al. CLINICAL CANCER RESEARCH
- microRNA-10b: A New Marker or the Marker of Pancreatic Ductal Adenocarcinoma?
- (2011) T. Setoyama et al. CLINICAL CANCER RESEARCH
- MicroRNA Molecular Profiles Associated with Diagnosis, Clinicopathologic Criteria, and Overall Survival in Patients with Resectable Pancreatic Ductal Adenocarcinoma
- (2011) N. B. Jamieson et al. CLINICAL CANCER RESEARCH
- Molecular mechanisms underlying the role of microRNAs (miRNAs) in anticancer drug resistance and implications for clinical practice
- (2011) Elisa Giovannetti et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- Occupational risk factors and pancreatic cancer: A review of recent findings
- (2011) Gabriella Andreotti et al. MOLECULAR CARCINOGENESIS
- Non-coding RNAs in human disease
- (2011) Manel Esteller NATURE REVIEWS GENETICS
- FOLFIRINOX versus Gemcitabine for Metastatic Pancreatic Cancer
- (2011) Thierry Conroy et al. NEW ENGLAND JOURNAL OF MEDICINE
- Molecular Pathogenesis of Pancreatic Cancer and Clinical Perspectives
- (2011) D. Matthaios et al. ONCOLOGY
- Elevated microRNA miR-21 Levels in Pancreatic Cyst Fluid Are Predictive of Mucinous Precursor Lesions of Ductal Adenocarcinoma
- (2011) Ji Kon Ryu et al. PANCREATOLOGY
- Targeting Epigenetic Regulation of miR-34a for Treatment of Pancreatic Cancer by Inhibition of Pancreatic Cancer Stem Cells
- (2011) Dara Nalls et al. PLoS One
- Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas
- (2011) Markus Vogt et al. VIRCHOWS ARCHIV
- MicroRNAmiR-17-5pis overexpressed in pancreatic cancer, associated with a poor prognosis, and involved in cancer cell proliferation and invasion
- (2010) Jun Yu et al. CANCER BIOLOGY & THERAPY
- miRNA-96 Suppresses KRAS and Functions as a Tumor Suppressor Gene in Pancreatic Cancer
- (2010) S. Yu et al. CANCER RESEARCH
- MicroRNA-21 in Pancreatic Cancer: Correlation with Clinical Outcome and Pharmacologic Aspects Underlying Its Role in the Modulation of Gemcitabine Activity
- (2010) Elisa Giovannetti et al. CANCER RESEARCH
- EGFR Promotes Lung Tumorigenesis by Activating miR-7 through a Ras/ERK/Myc Pathway That Targets the Ets2 Transcriptional Repressor ERF
- (2010) Y.-T. Chou et al. CANCER RESEARCH
- Gemcitabine Sensitivity Can Be Induced in Pancreatic Cancer Cells through Modulation of miR-200 and miR-21 Expression by Curcumin or Its Analogue CDF
- (2010) Shadan Ali et al. CANCER RESEARCH
- The miR-217 microRNA functions as a potential tumor suppressor in pancreatic ductal adenocarcinoma by targeting KRAS
- (2010) Wu-Gan Zhao et al. CARCINOGENESIS
- MicroRNA-21 Is Induced Early in Pancreatic Ductal Adenocarcinoma Precursor Lesions
- (2010) M. C. du Rieu et al. CLINICAL CHEMISTRY
- PALB2 mutations in European familial pancreatic cancer families
- (2010) EP Slater et al. CLINICAL GENETICS
- MicroRNA 483-3p suppresses the expression of DPC4/Smad4 in pancreatic cancer
- (2010) Jun Hao et al. FEBS LETTERS
- Stromal biology and therapy in pancreatic cancer
- (2010) A. Neesse et al. GUT
- Adjuvant Chemotherapy With Fluorouracil Plus Folinic Acid vs Gemcitabine Following Pancreatic Cancer Resection
- (2010) John P. Neoptolemos et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Randomized Phase III Trial of Gemcitabine Plus Cisplatin Compared With Single-Agent Gemcitabine As First-Line Treatment of Patients With Advanced Pancreatic Cancer: The GIP-1 Study
- (2010) Giuseppe Colucci et al. JOURNAL OF CLINICAL ONCOLOGY
- Dysregulation of miR-15a and miR-214 in human pancreatic cancer
- (2010) Xing J Zhang et al. Journal of Hematology & Oncology
- MicroRNA, hsa-miR-200c, is an independent prognostic factor in pancreatic cancer and its upregulation inhibits pancreatic cancer invasion but increases cell proliferation
- (2010) Jun Yu et al. Molecular Cancer
- miR-192/miR-215 Influence 5-Fluorouracil Resistance through Cell Cycle-Mediated Mechanisms Complementary to Its Post-transcriptional Thymidilate Synthase Regulation
- (2010) Valentina Boni et al. MOLECULAR CANCER THERAPEUTICS
- Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model
- (2010) Li Ma et al. NATURE BIOTECHNOLOGY
- Advanced pancreatic carcinoma: current treatment and future challenges
- (2010) Anastasios Stathis et al. Nature Reviews Clinical Oncology
- Human SMG-1 is Involved in Gemcitabine-Induced Primary microRNA-155/BIC Up-Regulation in Human Pancreatic Cancer PANC-1 Cells
- (2010) Qi-sheng Xia et al. PANCREAS
- Role of primary miRNA polymorphic variants in metastatic colon cancer patients treated with 5-fluorouracil and irinotecan
- (2010) V Boni et al. PHARMACOGENOMICS JOURNAL
- Identification of MicroRNA-21 as a Biomarker for Chemoresistance and Clinical Outcome Following Adjuvant Therapy in Resectable Pancreatic Cancer
- (2010) Jin-Hyeok Hwang et al. PLoS One
- MicroRNA-21 induces resistance to 5-fluorouracil by down-regulating human DNA MutS homolog 2 (hMSH2)
- (2010) N. Valeri et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Up-regulation of miR-200 and let-7 by Natural Agents Leads to the Reversal of Epithelial-to-Mesenchymal Transition in Gemcitabine-Resistant Pancreatic Cancer Cells
- (2009) Y. Li et al. CANCER RESEARCH
- HER2 overexpression correlates with survival after curative resection of pancreatic cancer
- (2009) Masahiro Komoto et al. CANCER SCIENCE
- Non-codingRNA sequence variations in human chronic lymphocytic leukemia and colorectal cancer
- (2009) Sylwia E. Wojcik et al. CARCINOGENESIS
- MicroRNAs and genomic variations: from Proteus tricks to Prometheus gift
- (2009) M. Fabbri et al. CARCINOGENESIS
- MiR-21 Indicates Poor Prognosis in Tongue Squamous Cell Carcinomas as an Apoptosis Inhibitor
- (2009) J. Li et al. CLINICAL CANCER RESEARCH
- SMAD4 Gene Mutations Are Associated with Poor Prognosis in Pancreatic Cancer
- (2009) A. Blackford et al. CLINICAL CANCER RESEARCH
- Elevated expression of microRNAs 155, 203, 210 and 222 in pancreatic tumors is associated with poorer survival
- (2009) Thomas Greither et al. INTERNATIONAL JOURNAL OF CANCER
- Phase III Randomized Comparison of Gemcitabine Versus Gemcitabine Plus Capecitabine in Patients With Advanced Pancreatic Cancer
- (2009) David Cunningham et al. JOURNAL OF CLINICAL ONCOLOGY
- DPC4 Gene Status of the Primary Carcinoma Correlates With Patterns of Failure in Patients With Pancreatic Cancer
- (2009) Christine A. Iacobuzio-Donahue et al. JOURNAL OF CLINICAL ONCOLOGY
- Small RNA: A Large Contributor to Carcinogenesis?
- (2009) Imran Bhatti et al. JOURNAL OF GASTROINTESTINAL SURGERY
- MicroRNA-200c mitigates invasiveness and restores sensitivity to microtubule-targeting chemotherapeutic agents
- (2009) D. R. Cochrane et al. MOLECULAR CANCER THERAPEUTICS
- MicroRNA-21 modulates biological functions of pancreatic cancer cells including their proliferation, invasion, and chemoresistance
- (2009) T. Moriyama et al. MOLECULAR CANCER THERAPEUTICS
- Next generation oncology drug development: opportunities and challenges
- (2009) Martin E. Gutierrez et al. Nature Reviews Clinical Oncology
- Causes and consequences of microRNA dysregulation in cancer
- (2009) Carlo M. Croce NATURE REVIEWS GENETICS
- Antisense Inhibition of microRNA-21 or -221 Arrests Cell Cycle, Induces Apoptosis, and Sensitizes the Effects of Gemcitabine in Pancreatic Adenocarcinoma
- (2009) Jong-Kook Park et al. PANCREAS
- MicroRNA miR-34 Inhibits Human Pancreatic Cancer Tumor-Initiating Cells
- (2009) Qing Ji et al. PLoS One
- Regulation of HIF-1α and VEGF by miR-20b Tunes Tumor Cells to Adapt to the Alteration of Oxygen Concentration
- (2009) Zhang Lei et al. PLoS One
- Exomic Sequencing Identifies PALB2 as a Pancreatic Cancer Susceptibility Gene
- (2009) S. Jones et al. SCIENCE
- Role of MicroRNA miR-27a and miR-451 in the regulation of MDR1/P-glycoprotein expression in human cancer cells
- (2008) Hua Zhu et al. BIOCHEMICAL PHARMACOLOGY
- Meta-analysis of randomized trials: evaluation of benefit from gemcitabine-based combination chemotherapy applied in advanced pancreatic cancer
- (2008) Volker Heinemann et al. BMC CANCER
- Coordinated Epidermal Growth Factor Receptor Pathway Gene Overexpression Predicts Epidermal Growth Factor Receptor Inhibitor Sensitivity in Pancreatic Cancer
- (2008) A. Jimeno et al. CANCER RESEARCH
- Regulation of Epidermal Growth Factor Receptor Signaling in Human Cancer Cells by MicroRNA-7
- (2008) Rebecca J. Webster et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The role of microRNA expression pattern in human intrahepatic cholangiocarcinoma
- (2008) Lei Chen et al. JOURNAL OF HEPATOLOGY
- MicroRNA-10a Binds the 5′UTR of Ribosomal Protein mRNAs and Enhances Their Translation
- (2008) Ulf Andersson Ørom et al. MOLECULAR CELL
- MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation
- (2008) Yvonne Tay et al. NATURE
- Circulating microRNAs as stable blood-based markers for cancer detection
- (2008) P. S. Mitchell et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses
- (2008) S. Jones et al. SCIENCE
- MicroRNAs: Control and Loss of Control in Human Physiology and Disease
- (2008) Min Li et al. WORLD JOURNAL OF SURGERY
- Quantitative differential expression analysis reveals miR-7 as major islet microRNA
- (2007) Valia Bravo-Egana et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Pancreatic Cancer–Associated Diabetes Mellitus: Prevalence and Temporal Association With Diagnosis of Cancer
- (2007) Suresh T. Chari et al. GASTROENTEROLOGY
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started