Current and Emerging Biomarkers of Cell Death in Human Disease

RIP Kinase-Mediated Necrosis as an Alternative Mechanisms of Photoreceptor Death

(2015) Yusuke Murakami et al.   Oncotarget

MDM2-p53 Interaction in Paediatric Solid Tumours: Preclinical Rationale, Biomarkers and Resistance

(2014) Giuseppe Barone et al.   CURRENT DRUG TARGETS

The impact of PKR activation: from neurodegeneration to cancer

(2014) Juan A. Marchal et al.   FASEB JOURNAL

Human cytomegalovirus suppresses Fas expression and function

(2014) S. Seirafian et al.   JOURNAL OF GENERAL VIROLOGY

Biomarkers of liver cell death

(2014) Akiko Eguchi et al.   JOURNAL OF HEPATOLOGY

Imaging Cell Death

(2014) A. A. Neves et al.   JOURNAL OF NUCLEAR MEDICINE

Self-consumption: the interplay of autophagy and apoptosis

(2014) Guillermo Mariño et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Molecular mechanisms of regulated necrosis

(2014) Lorenzo Galluzzi et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

p53-dependent Fas expression is critical for Ginsenoside Rh2 triggered caspase-8 activation in HeLa cells

(2014) Xiao-Xi Guo et al.   Protein & Cell

Coordination of autophagy with other cellular activities

(2013) Yan Wang et al.   ACTA PHARMACOLOGICA SINICA

Serum Cytokeratin-18 Fragment Levels Are Useful Biomarkers for Nonalcoholic Steatohepatitis in Children

(2013) Ariel E Feldstein et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Connect the dots

(2013) Yifei Li et al.   Autophagy

Soluble FAS ligand as a biomarker of disease recurrence in differentiated thyroid cancer

(2013) Taofeek K. Owonikoko et al.   CANCER

The non-coding transcriptome as a dynamic regulator of cancer metastasis

(2013) Francesco Crea et al.   CANCER AND METASTASIS REVIEWS

MicroRNA-181a enhances the chemoresistance of human cervical squamous cell carcinoma to cisplatin by targeting PRKCD

(2013) Yiran Chen et al.   EXPERIMENTAL CELL RESEARCH

Emerging trends of long non-coding RNAs in gene activation

(2013) Jaya Krishnan et al.   FEBS Journal

TRAIL mRNA expression in peripheral blood mononuclear cells of Egyptian SLE patients

(2013) Safaa Mostafa El-Karaksy et al.   GENE

Noncoding RNA in Oncogenesis: A New Era of Identifying Key Players

(2013) Guorui Deng et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Interconnections between apoptotic, autophagic and necrotic pathways: implications for cancer therapy development

(2013) Mayur V. Jain et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

TNF-Alpha Levels in Tears: A Novel Biomarker to Assess the Degree of Diabetic Retinopathy

(2013) C. Costagliola et al.   MEDIATORS OF INFLAMMATION

Autophagy in Human Health and Disease

(2013)   NEW ENGLAND JOURNAL OF MEDICINE

MicroRNA-497 is a potential prognostic marker in human cervical cancer and functions as a tumor suppressor by targeting the insulin-like growth factor 1 receptor

(2013) Min Luo et al.   SURGERY

A Role of RIP3-Mediated Macrophage Necrosis in Atherosclerosis Development

(2013) Juan Lin et al.   Cell Reports

MicroRNA-21 in the pathogenesis of acute kidney injury

(2013) Ya-Feng Li et al.   Protein & Cell

Role of the Crosstalk between Autophagy and Apoptosis in Cancer

(2013) Minfei Su et al.   Journal of Oncology

MicroRNAs in autophagy and their emerging roles in crosstalk with apoptosis

(2012) Jianzhen Xu et al.   Autophagy

Cellular and molecular mechanisms of muscle atrophy

(2012) P. Bonaldo et al.   Disease Models & Mechanisms

Autophagy and cancer

(2012) Kyeong Sook Choi   EXPERIMENTAL AND MOLECULAR MEDICINE

Molecules and their functions in autophagy

(2012) Jong-Ok Pyo et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

DNA damage-induced sustained p53 activation contributes to inflammation-associated hepatocarcinogenesis in rats

(2012) H-X Yan et al.   ONCOGENE

BMK1 is involved in the regulation of p53 through disrupting the PML–MDM2 interaction

(2012) Q Yang et al.   ONCOGENE

Programmed Cell Death in Animal Development and Disease

(2011) Yaron Fuchs et al.   CELL

Cell death by autophagy: facts and apparent artefacts

(2011) D Denton et al.   CELL DEATH AND DIFFERENTIATION

Dying for a cause: NETosis, mechanisms behind an antimicrobial cell death modality

(2011) Q Remijsen et al.   CELL DEATH AND DIFFERENTIATION

Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

(2011) L Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Chromosomal breaks during mitotic catastrophe trigger γH2AX–ATM–p53-mediated apoptosis

(2011) Gabriela Imreh et al.   JOURNAL OF CELL SCIENCE

Deregulated miR-155 promotes Fas-mediated apoptosis in human intervertebral disc degeneration by targeting FADD and caspase-3

(2011) Hai-Qiang Wang et al.   JOURNAL OF PATHOLOGY

FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation

(2011) Patrick-Simon Welz et al.   NATURE

Mitotic catastrophe: a mechanism for avoiding genomic instability

(2011) Ilio Vitale et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

TRAIL-induced apoptosis of human melanoma cells involves activation of caspase-4

(2010) Zhi Gang Mao et al.   APOPTOSIS

Cytoskeletal keratin glycosylation protects epithelial tissue from injury

(2010) Nam-On Ku et al.   NATURE CELL BIOLOGY

The role of defective clearance of apoptotic cells in systemic autoimmunity

(2010) Luis E. Muñoz et al.   Nature Reviews Rheumatology

MicroRNAs identified in highly purified liver-derived mitochondria may play a role in apoptosis

(2010) Betsy T. Kren et al.   RNA Biology

Shaping Development of Autophagy Inhibitors with the Structure of the Lipid Kinase Vps34

(2010) S. Miller et al.   SCIENCE

The Role of the Kinases RIP1 and RIP3 in TNF-Induced Necrosis

(2010) P. Vandenabeele et al.   Science Signaling

Systematic review: caspase-cleaved fragments of cytokeratin 18 - the promises and challenges of a biomarker for chronic liver disease

(2009) Y. YILMAZ   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Measuring soluble forms of extracellular cytokeratin 18 identifies both apoptotic and necrotic mechanisms of cell death produced by adenoviral-mediated interferon α: possible use as a surrogate marker

(2009) M B Fisher et al.   CANCER GENE THERAPY

Caspase activation pathways: some recent progress

(2009) S P Cullen et al.   CELL DEATH AND DIFFERENTIATION

Mechanisms of Drug-Induced Mitotic Catastrophe in Cancer Cells

(2009) Jose Portugal et al.   CURRENT PHARMACEUTICAL DESIGN

Life and death by death receptors

(2009) Maria Eugenia Guicciardi et al.   FASEB JOURNAL

Human Caspases: Activation, Specificity, and Regulation

(2009) Cristina Pop et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Caspases: evolutionary aspects of their functions in vertebrates

(2009) K. Sakamaki et al.   JOURNAL OF FISH BIOLOGY

Apoptosis and cancer: mutations within caspase genes

(2009) S Ghavami et al.   JOURNAL OF MEDICAL GENETICS

RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis

(2009) D.-W. Zhang et al.   SCIENCE

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

(2008) G Kroemer et al.   CELL DEATH AND DIFFERENTIATION

Crosstalk Between Autophagy and Apoptosis in Heart Disease

(2008) Kazuhiko Nishida et al.   CIRCULATION RESEARCH

Apoptosis Regulators Bim and Fas Function Concurrently to Control Autoimmunity and CD8+ T Cell Contraction

(2008) Ashley E. Weant et al.   IMMUNITY