Experimental Evidence ofω-3 Polyunsaturated Fatty Acid Modulation of Inflammatory Cytokines and Bioactive Lipid Mediators: Their Potential Role in Inflammatory, Neurodegenerative, and Neoplastic Diseases

Mitochondrial Alterations, Oxidative Stress and Neuroinflammation in Alzheimer's Disease

(2017) M. Verri et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

A prospective cohort study on risk of acute pancreatitis related to serum triglycerides, cholesterol and fasting glucose

(2013) Björn Lindkvist et al.   PANCREATOLOGY

Omega-3 Fatty Acids Ameliorate Atherosclerosis by Favorably Altering Monocyte Subsets and Limiting Monocyte Recruitment to Aortic Lesions

(2012) Amanda L. Brown et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Endogenously synthesized n-3 polyunsaturated fatty acids in fat-1 mice ameliorate high-fat diet-induced non-alcoholic fatty liver disease

(2012) Eun-Hee Kim et al.   BIOCHEMICAL PHARMACOLOGY

DHA induces apoptosis by altering the expression and cellular location of GRP78 in colon cancer cell lines

(2012) Elena Fasano et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Omega-3 polyunsaturated fatty acids and inflammatory processes: nutrition or pharmacology?

(2012) Philip C. Calder   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Inflammation and Coronary Artery Disease: Insights From Genetic Studies

(2012) Ruth McPherson et al.   CANADIAN JOURNAL OF CARDIOLOGY

Abdominal Obesity and Cardiovascular Disease: Is Inflammation the Missing Link?

(2012) Jean-Pierre Després   CANADIAN JOURNAL OF CARDIOLOGY

Consumption of n-3 Fatty Acids and Fish Reduces Risk of Hepatocellular Carcinoma

(2012) Norie Sawada et al.   GASTROENTEROLOGY

Omega-6 docosapentaenoic acid-derived resolvins and 17-hydroxydocosahexaenoic acid modulate macrophage function and alleviate experimental colitis

(2012) Cheng-Ying Chiu et al.   INFLAMMATION RESEARCH

Fatty acids in cardiovascular health and disease: A comprehensive update

(2012) Seth J. Baum et al.   Journal of Clinical Lipidology

Titrating lovaza from 4 to 8 to 12 grams/day in patients with primary hypertriglyceridemia who had triglyceride levels >500 mg/dl despite conventional triglyceride lowering therapy

(2012) Charles J Glueck et al.   Lipids in Health and Disease

Fish Oil Improves the Lipid Profile and Reduces Inflammatory Cytokines in Wistar Rats With Precancerous Colon Lesions

(2012) Damiana Diniz Rosa et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Omega-3 fatty acids and their lipid mediators: Towards an understanding of resolvin and protectin formation

(2012) Karsten H. Weylandt et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Colorectal Cancer Chemoprevention: Is This the Future of Colorectal Cancer Prevention?

(2012) A. Manzano et al.   TheScientificWorldJOURNAL

Carcinoma origin dictates differential skewing of monocyte function

(2012) Marijn Bögels et al.   OncoImmunology

Parenteral fish-oil-based lipid emulsion improves fatty acid profiles and lipids in parenteral nutrition-dependent children

(2011) H. D. Le et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Multifaceted link between cancer and inflammation

(2011) Gautam Sethi et al.   BIOSCIENCE REPORTS

Effect of n-3 fatty acids on patients with advanced lung cancer: a double-blind, placebo-controlled study

(2011) Concetta Finocchiaro et al.   BRITISH JOURNAL OF NUTRITION

Role of lipoxins, resolvins, and other bioactive lipids in colon and pancreatic cancer

(2011) Naveena B. Janakiram et al.   CANCER AND METASTASIS REVIEWS

Effects of high-fat diets rich in either omega-3 or omega-6 fatty acids on UVB-induced skin carcinogenesis in SKH-1 mice

(2011) Y.-R. Lou et al.   CARCINOGENESIS

DHA induces apoptosis and differentiation in human melanoma cells in vitro : involvement of HuR-mediated COX-2 mRNA stabilization and β-catenin nuclear translocation

(2011) Simona Serini et al.   CARCINOGENESIS

Suppressed liver tumorigenesis in fat-1 mice with elevated omega-3 fatty acids is associated with increased omega-3 derived lipid mediators and reduced TNF- 

(2011) K. H. Weylandt et al.   CARCINOGENESIS

Anti-inflammatory and anti-angiogenic effect of long chain n-3 polyunsaturated fatty acids in intestinal microvascular endothelium

(2011) Ayman Ibrahim et al.   CLINICAL NUTRITION

Differential Anti-Cancer Effects of Purified EPA and DHA and Possible Mechanisms Involved

(2011) S. Serini et al.   CURRENT MEDICINAL CHEMISTRY

Docosahexaenoic Acid-Derived Neuroprotectin D1 Induces Neuronal Survival via Secretase- and PPARγ-Mediated Mechanisms in Alzheimer's Disease Models

(2011) Yuhai Zhao et al.   PLoS One

Analysis of omega-3 and omega-6 fatty acid-derived lipid metabolite formation in human and mouse blood samples

(2011) Beate Gomolka et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Cancer-related inflammation: Common themes and therapeutic opportunities

(2011) Frances R. Balkwill et al.   SEMINARS IN CANCER BIOLOGY

Non-mammalian fat-1 gene prevents neoplasia when introduced to a mouse hepatocarcinogenesis modelOmega-3 fatty acids prevent liver neoplasia

(2010) J. Griffitts et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Inflammation-mediated promotion of invasion and metastasis

(2010) Graziella Solinas et al.   CANCER AND METASTASIS REVIEWS

Docosahexaenoic acid alters epidermal growth factor receptor-related signaling by disrupting its lipid raft association

(2010) Kristina R. Rogers et al.   CARCINOGENESIS

Eicosapentaenoic acid reduces rectal polyp number and size in familial adenomatous polyposis

(2010) N. J. West et al.   GUT

Mechanisms of n-3 fatty acid-mediated development and maintenance of learning memory performance

(2010) Hui-Min Su   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Cox-2 expression, PGE2 and cytokines production are inhibited by endogenously synthesized n-3 PUFAs in inflamed colon of fat-1 mice

(2010) Claudia Gravaghi et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Docosahexaenoic acid reverts resistance to UV-induced apoptosis in human keratinocytes: involvement of COX-2 and HuR

(2010) Simona Serini et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Effects of omega-3 fatty acids on components of the transforming growth factor beta-1 pathway: implication for dietary modification and prevention in ovarian cancer

(2009) Arun Sharma et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Inhibitory Mechanism of Omega-3 Fatty Acids in Pancreatic Inflammation and Apoptosis

(2009) Kyung Suk Park et al.   Annals of the New York Academy of Sciences

Synergistic anti-inflammatory effects of low doses of curcumin in combination with polyunsaturated fatty acids: Docosahexaenoic acid or eicosapentaenoic acid

(2009) Constance Lay Lay Saw et al.   BIOCHEMICAL PHARMACOLOGY

Effects of Omega-3 Fatty Acids on Inflammatory Markers in Cerebrospinal Fluid and Plasma in Alzheimer’s Disease: The OmegAD Study

(2009) Yvonne Freund-Levi et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

The Epidermal Growth Factor Receptor: A Link Between Inflammation and Liver Cancer

(2009) Carmen Berasain et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Obesity-induced insulin resistance and hepatic steatosis are alleviated by ω-3 fatty acids: a role for resolvins and protectins

(2009) Ana González-Périz et al.   FASEB JOURNAL

The plasma lipidomic signature of nonalcoholic steatohepatitis

(2009) Puneet Puri et al.   HEPATOLOGY

Cellular and molecular pathways linking inflammation and cancer

(2009) Chiara Porta et al.   IMMUNOBIOLOGY

Reduced prostaglandin F2α release from blood mononuclear leukocytes after oral supplementation of ω3 fatty acids: the OmegAD study

(2009) Inger Vedin et al.   JOURNAL OF LIPID RESEARCH

Mechanism of docosahexaenoic acid-induced inhibition ofin vitroAβ1-42fibrillation and Aβ1-42-induced toxicity in SH-S5Y5 cells

(2009) Shahdat Hossain et al.   JOURNAL OF NEUROCHEMISTRY

Are all n-3 polyunsaturated fatty acids created equal?

(2009) Breanne M Anderson et al.   Lipids in Health and Disease

Antineoplastic Effects of N-3 Polyunsaturated Fatty Acids in Combination With Drugs and Radiotherapy: Preventive and Therapeutic Strategies

(2009) G. Calviello et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

α-Linolenic acid supplementation and conversion to n-3 long-chain polyunsaturated fatty acids in humans

(2009) J. Thomas Brenna et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Eicosapentaenoic acid inhibits TNF-α-induced matrix metalloproteinase-9 expression in human keratinocytes, HaCaT cells

(2008) Hyeon Ho Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Reduction of inflammation and chronic tissue damage by omega-3 fatty acids in fat-1 transgenic mice with pancreatitis

(2008) Karsten H. Weylandt et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Reduced Colitis-Associated Colon Cancer in Fat-1 (n-3 Fatty Acid Desaturase) Transgenic Mice

(2008) Q. Jia et al.   CANCER RESEARCH

Alzheimers Disease and n-3 Polyunsaturated Fatty Acids: Beneficial Effects and Possible Molecular Pathways Involved

(2008) Gabriella Calviello et al.   Current Signal Transduction Therapy

Omega-3 Free Fatty Acids for the Maintenance of Remission in Crohn Disease

(2008) Brian G. Feagan et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Experimental models and mechanisms underlying the protective effects of n-3 polyunsaturated fatty acids in Alzheimer's disease

(2008) Cynthia Boudrault et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

The protective effect of dietary eicosapentaenoic acid against impairment of spatial cognition learning ability in rats infused with amyloid β(1–40)

(2008) Michio Hashimoto et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

ω-3 Fatty Acids–Supplemented Parenteral Nutrition Decreases Hyperinflammatory Response and Attenuates Systemic Disease Sequelae in Severe Acute Pancreatitis: A Randomized and Controlled Study

(2008) Xinying Wang et al.   JOURNAL OF PARENTERAL AND ENTERAL NUTRITION

Cancer-related inflammation

(2008) Alberto Mantovani et al.   NATURE

Macrophage polarization in tumour progression

(2008) Antonio Sica et al.   SEMINARS IN CANCER BIOLOGY