Tight Coordination of Protein Translation and HSF1 Activation Supports the Anabolic Malignant State
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Title
Tight Coordination of Protein Translation and HSF1 Activation Supports the Anabolic Malignant State
Authors
Keywords
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Journal
SCIENCE
Volume 341, Issue 6143, Pages 1238303-1238303
Publisher
American Association for the Advancement of Science (AAAS)
Online
2013-07-19
DOI
10.1126/science.1238303
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- (2012) L. Whitesell et al. CURRENT MOLECULAR MEDICINE
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- (2011) Xiongjie Jin et al. Cell Metabolism
- Synthesis of Rocaglamide Hydroxamates and Related Compounds as Eukaryotic Translation Inhibitors: Synthetic and Biological Studies
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- Antitumor Activity and Mechanism of Action of the Cyclopenta[b]benzofuran, Silvestrol
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