Mycobacterium tuberculosis ClpP1 and ClpP2 Function Together in Protein Degradation and Are Required for Viability in vitro and During Infection

The Natural Product Cyclomarin Kills Mycobacterium Tuberculosis by Targeting the ClpC1 Subunit of the Caseinolytic Protease

(2011) Esther K. Schmitt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Identifying Vulnerable Pathways in Mycobacterium tuberculosis by Using a Knockdown Approach

(2011) Paul Carroll et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Depletion of antibiotic targets has widely varying effects on growth

(2011) J.-R. Wei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prokaryotic Ubiquitin-Like Protein Provides a Two-Part Degron to Mycobacterium Proteasome Substrates

(2010) K. E. Burns et al.   JOURNAL OF BACTERIOLOGY

ClgR regulation of chaperone and protease systems is essential for Mycobacterium tuberculosis parasitism of the macrophage

(2010) M. Estorninho et al.   MICROBIOLOGY-SGM

Molecular analysis of the prokaryotic ubiquitin-like protein (Pup) conjugation pathway in Mycobacterium tuberculosis

(2010) Francisca A. Cerda-Maira et al.   MOLECULAR MICROBIOLOGY

Emerging principles in protease-based drug discovery

(2010) Marcin Drag et al.   NATURE REVIEWS DRUG DISCOVERY

Characterization of a Clp Protease Gene Regulator and the Reaeration Response in Mycobacterium tuberculosis

(2010) Ashley M. Sherrid et al.   PLoS One

The antibiotic ADEP reprogrammes ClpP, switching it from a regulated to an uncontrolled protease

(2009) Janine Kirstein et al.   EMBO Molecular Medicine

Proteases in bacterial pathogenesis

(2009) Hanne Ingmer et al.   RESEARCH IN MICROBIOLOGY

Mycobacterium tuberculosis ftsH expression in response to stress and viability

(2009) Manjot Kiran et al.   TUBERCULOSIS

β-Lactones as Specific Inhibitors of ClpP Attenuate the Production of Extracellular Virulence Factors ofStaphylococcus aureus

(2008) Thomas Böttcher et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Controlled degradation by ClpXP protease tunes the levels of the excision repair protein UvrA to the extent of DNA damage

(2008) Mihaela Pruteanu et al.   MOLECULAR MICROBIOLOGY