p53 Up-regulated Modulator of Apoptosis (PUMA) Activation Contributes to Pancreatic β-Cell Apoptosis Induced by Proinflammatory Cytokines and Endoplasmic Reticulum Stress

Signaling by IL-1β+IFN-γ and ER stress converge on DP5/Hrk activation: a novel mechanism for pancreatic β-cell apoptosis

(2009) E N Gurzov et al.   CELL DEATH AND DIFFERENTIATION

PUMA is directly activated by NF-κB and contributes to TNF-α-induced apoptosis

(2009) P Wang et al.   CELL DEATH AND DIFFERENTIATION

Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes

(2009) L Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Islet  -Cells Deficient in Bcl-xL Develop but Are Abnormally Sensitive to Apoptotic Stimuli

(2009) E. M. Carrington et al.   DIABETES

Glucose Induces Pancreatic Islet Cell Apoptosis That Requires the BH3-Only Proteins Bim and Puma and Multi-BH Domain Protein Bax

(2009) M. D. McKenzie et al.   DIABETES

Proinflammatory Cytokines Activate the Intrinsic Apoptotic Pathway in  -Cells

(2009) L. G. Grunnet et al.   DIABETES

PTPN2, a Candidate Gene for Type 1 Diabetes, Modulates Interferon- -Induced Pancreatic  -Cell Apoptosis

(2009) F. Moore et al.   DIABETES

JNK1-dependent PUMA Expression Contributes to Hepatocyte Lipoapoptosis

(2009) Sophie C. Cazanave et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Puma strikes Bax: Figure 1.

(2009) Anthony Letai   JOURNAL OF CELL BIOLOGY

Bax activation by the BH3-only protein Puma promotes cell dependence on antiapoptotic Bcl-2 family members

(2009) Tristan Gallenne et al.   JOURNAL OF CELL BIOLOGY

The Bcl-2 Family Antagonist ABT-737 Significantly Inhibits Multiple Animal Models of Autoimmunity

(2009) P. D. Bardwell et al.   JOURNAL OF IMMUNOLOGY

Stepwise Activation of BAX and BAK by tBID, BIM, and PUMA Initiates Mitochondrial Apoptosis

(2009) Hyungjin Kim et al.   MOLECULAR CELL

The role of inflammation in insulitis and β-cell loss in type 1 diabetes

(2009) Décio L. Eizirik et al.   Nature Reviews Endocrinology

Role of NF-κB in β-cell death: Figure 1

(2008) Danielle Melloul   BIOCHEMICAL SOCIETY TRANSACTIONS

Proapoptotic BH3-Only Protein Bid Is Essential For Death Receptor-Induced Apoptosis of Pancreatic  -Cells

(2008) M. D. McKenzie et al.   DIABETES

Initiation and execution of lipotoxic ER stress in pancreatic  -cells

(2008) D. A. Cunha et al.   JOURNAL OF CELL SCIENCE

Cytokine-induced β-cell apoptosis is NO-dependent, mitochondria-mediated and inhibited by BCL-XL

(2008) C. Holohan et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

JunB Inhibits ER Stress and Apoptosis in Pancreatic Beta Cells

(2008) Esteban N. Gurzov et al.   PLoS One

Bcl-XL Inhibits Membrane Permeabilization by Competing with Bax

(2008) Lieven P Billen et al.   PLOS BIOLOGY

The BCL-2 protein family: opposing activities that mediate cell death

(2007) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY