Inhibition of cAMP-Activated Intestinal Chloride Secretion by Diclofenac: Cellular Mechanism and Potential Application in Cholera

High-throughput fluorescent-based NKCC functional assay in adherent epithelial cells

(2013) Monica Carmosino et al.   BMC CELL BIOLOGY

Cholera: pathophysiology and emerging therapeutic targets

(2013) Chatchai Muanprasat et al.   Future Medicinal Chemistry

Chloride channel inhibition by a red wine extract and a synthetic small molecule prevents rotaviral secretory diarrhoea in neonatal mice

(2013) Eun-A Ko et al.   GUT

An Adult Mouse Model of Vibrio cholerae-induced Diarrhea for Studying Pathogenesis and Potential Therapy of Cholera

(2013) Sutthipong Sawasvirojwong et al.   PLoS Neglected Tropical Diseases

CFTR Inhibitors for Treating Diarrheal Disease

(2012) J R Thiagarajah et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Insights into the effects of diclofenac and other non-steroidal anti-inflammatory agents on ion channels

(2012) Asfree Gwanyanya et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Cholera

(2012) Jason B Harris et al.   LANCET

Hydroxyxanthone as an inhibitor of cAMP-activated apical chloride channel in human intestinal epithelial cell

(2012) Wachiraporn Luerang et al.   LIFE SCIENCES

Novel Action of the Chalcone Isoliquiritigenin as a Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Inhibitor: Potential Therapy for Cholera and Polycystic Kidney Disease

(2011) Chatchai Muanprasat et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Rotavirus toxin NSP4 induces diarrhea by activation of TMEM16A and inhibition of Na+ absorption

(2011) Jiraporn Ousingsawat et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Disruption of the K+Channel β-Subunit KCNE3 Reveals an Important Role in Intestinal and Tracheal Cl−Transport

(2010) Patricia Preston et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Diclofenac potassium liquid-filled soft gelatin capsules in the management of patients with postbunionectomy pain: A phase III, multicenter, randomized, double-blind, placebo-controlled study conducted over 5 days

(2009) Dennis S. Riff et al.   CLINICAL THERAPEUTICS

Epac1 mediates protein kinase A–independent mechanism of forskolin-activated intestinal chloride secretion

(2009) Kazi Mirajul Hoque et al.   JOURNAL OF GENERAL PHYSIOLOGY

Chloride channels as drug targets

(2009) Alan S. Verkman et al.   NATURE REVIEWS DRUG DISCOVERY

Is 1-Aminobenzotriazole an Appropriate in Vitro Tool as a Nonspecific Cytochrome P450 Inactivator?

(2008) C. D. Linder et al.   DRUG METABOLISM AND DISPOSITION

Mechanistic Insight into Control of CFTR by AMPK

(2008) Patthara Kongsuphol et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dose translation from animal to human studies revisited

(2007) Shannon Reagan-Shaw et al.   FASEB JOURNAL