Human dCTP pyrophosphatase 1 promotes breast cancer cell growth and stemness through the modulation on 5-methyl-dCTP metabolism and global hypomethylation

Targeting the MUC1-C oncoprotein inhibits self-renewal capacity of breast cancer cells

(2015) Maroof Alam et al.   Oncotarget

The NTP pyrophosphatase DCTPP1 contributes to the homoeostasis and cleansing of the dNTP pool in human cells

(2014) Cristina E. Requena et al.   BIOCHEMICAL JOURNAL

Comparative Proteomics Analysis of Gastric Cancer Stem Cells

(2014) Tamami Morisaki et al.   PLoS One

5-Methyldeoxycytidine enhances the substrate activity of DNA polymerase

(2013) Tian Tian et al.   CHEMICAL COMMUNICATIONS

dCTP pyrophosphohydrase exhibits nucleic accumulation in multiple carcinomas

(2013) Y. Zhang et al.   EUROPEAN JOURNAL OF HISTOCHEMISTRY

Hypomethylation signature of tumor-initiating cells predicts poor prognosis of ovarian cancer patients

(2013) Yu-Ping Liao et al.   HUMAN MOLECULAR GENETICS

Mycobacterial MazG Safeguards Genetic Stability via Housecleaning of 5-OH-dCTP

(2013) Liang-Dong Lyu et al.   PLoS Pathogens

The emerging role of DNA methylation in epileptogenesis

(2012) Katja Kobow et al.   EPILEPSIA

Triptolide Directly Inhibits dCTP Pyrophosphatase

(2011) Timothy W. Corson et al.   CHEMBIOCHEM

Inhibition of dUTPase Induces Synthetic Lethality with Thymidylate Synthase-Targeted Therapies in Non-Small Cell Lung Cancer

(2011) P. M. Wilson et al.   MOLECULAR CANCER THERAPEUTICS

Mycobacterial MazG Is a Novel NTP Pyrophosphohydrolase Involved in Oxidative Stress Response

(2010) Liang-dong Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ABCG2: A potential marker of stem cells and novel target in stem cell and cancer therapy

(2010) Xi-wei Ding et al.   LIFE SCIENCES

Oxidation in the nucleotide pool, the DNA damage response and cellular senescence: Defective bricks build a defective house

(2010) Priyamvada Rai   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Enhanced elimination of oxidized guanine nucleotides inhibits oncogenic RAS-induced DNA damage and premature senescence

(2010) P Rai et al.   ONCOGENE

An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients

(2009) Balazs Györffy et al.   BREAST CANCER RESEARCH AND TREATMENT

Incorporation of 5-chlorocytosine into mammalian DNA results in heritable gene silencing and altered cytosine methylation patterns

(2009) V. V. Lao et al.   CARCINOGENESIS

Mouse RS21-C6 is a mammalian 2′-deoxycytidine 5′-triphosphate pyrophosphohydrolase that prefers 5-iodocytosine

(2009) Mari Nonaka et al.   FEBS Journal

dUTP pyrophosphatase expression correlates with a poor prognosis in hepatocellular carcinoma

(2009) Hajime Takatori et al.   LIVER INTERNATIONAL

Examination of Hypochlorous Acid-Induced Damage to Cytosine Residues in a CpG Dinucleotide in DNA

(2008) Joseph I. Kang et al.   CHEMICAL RESEARCH IN TOXICOLOGY