The small GTPase RAB-35 defines a third pathway that is required for the recognition and degradation of apoptotic cells

Apoptosis and Clearance of Apoptotic Cells

(2018) Shigekazu Nagata   Annual Review of Immunology

Rab35 protein regulates evoked exocytosis of endothelial Weibel–Palade bodies

(2017) Anja Biesemann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Folliculin Interacts with Rab35 to Regulate EGF-Induced EGFR Degradation

(2017) Jianchao Zheng et al.   Frontiers in Pharmacology

Programmed Cell Death During Caenorhabditis elegans Development

(2016) Barbara Conradt et al.   GENETICS

The life cycle of phagosomes: formation, maturation, and resolution

(2016) Roni Levin et al.   IMMUNOLOGICAL REVIEWS

Activity-Dependent Degradation of Synaptic Vesicle Proteins Requires Rab35 and the ESCRT Pathway

(2016) Patricia Sheehan et al.   JOURNAL OF NEUROSCIENCE

Rab35 GTPase: A Central Regulator of Phosphoinositides and F-actin in Endocytic Recycling and Beyond

(2016) Kerstin Klinkert et al.   TRAFFIC

Programmed Cell Death During Caenorhabditis elegans Development

(2016) Barbara Conradt et al.   GENETICS

PtdIns(4,5)P2and PtdIns3P coordinate to regulate phagosomal sealing for apoptotic cell clearance

(2015) Shiya Cheng et al.   JOURNAL OF CELL BIOLOGY

Identification of an oncogenic RAB protein

(2015) D. B. Wheeler et al.   SCIENCE

New genetic regulators question relevance of abundant yolk protein production in C. elegans

(2015) Liesbeth Van Rompay et al.   Scientific Reports

Age-Specific Cancer Incidence Rates Increase Through the Oldest Age Groups

(2014) Jigisha P. Thakkar et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

The autophagic roles of Rab small GTPases and their upstream regulators

(2014) Zsuzsanna Szatmári et al.   Autophagy

Small GTPase CDC-42 promotes apoptotic cell corpse clearance in response to PAT-2 and CED-1 in C. elegans

(2014) L J Neukomm et al.   CELL DEATH AND DIFFERENTIATION

The role of the hypervariable C-terminal domain in Rab GTPases membrane targeting

(2014) F. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phagocytic receptor signaling regulates clathrin and epsin-mediated cytoskeletal remodeling during apoptotic cell engulfment in C. elegans

(2013) Q. Shen et al.   DEVELOPMENT

Membrane extraction of Rab proteins by GDP dissociation inhibitor characterized using attenuated total reflection infrared spectroscopy

(2013) K. Gavriljuk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An ARF6/Rab35 GTPase Cascade for Endocytic Recycling and Successful Cytokinesis

(2012) Laurent Chesneau et al.   CURRENT BIOLOGY

The C. elegans Rab Family: Identification, Classification and Toolkit Construction

(2012) Maria E. Gallegos et al.   PLoS One

LAAT-1 Is the Lysosomal Lysine/Arginine Transporter That Maintains Amino Acid Homeostasis

(2012) B. Liu et al.   SCIENCE

Crystal structure of folliculin reveals a hidDENN function in genetically inherited renal cancer

(2012) R. K. Nookala et al.   Open Biology

Two PI 3-Kinases and One PI 3-Phosphatase Together Establish the Cyclic Waves of Phagosomal PtdIns(3)P Critical for the Degradation of Apoptotic Cells

(2012) Nan Lu et al.   PLOS BIOLOGY

Integrin α PAT-2/CDC-42 Signaling Is Required for Muscle-Mediated Clearance of Apoptotic Cells in Caenorhabditis elegans

(2012) Hsiao-Han Hsieh et al.   PLoS Genetics

Crystal structure of the cell corpse engulfment protein CED-2 in Caenorhabditis elegans

(2011) Yanyong Kang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Rab35 regulates phagosome formation through recruitment of ACAP2 in macrophages during Fc R-mediated phagocytosis

(2011) Y. Egami et al.   JOURNAL OF CELL SCIENCE

Rab35 GTPase and OCRL phosphatase remodel lipids and F-actin for successful cytokinesis

(2011) Daphné Dambournet et al.   NATURE CELL BIOLOGY

One lipid, multiple functions: how various pools of PI(4,5)P2 are created in the plasma membrane

(2010) Katarzyna Kwiatkowska   CELLULAR AND MOLECULAR LIFE SCIENCES

Apoptosis: Conserved Roles for Integrins in Clearance

(2010) Veera D'mello et al.   CURRENT BIOLOGY

Engulfment of Apoptotic Cells in C. elegans Is Mediated by Integrin α/SRC Signaling

(2010) Tsung-Yuan Hsu et al.   CURRENT BIOLOGY

Recycling of the Ca2+-activated K+Channel, KCa2.3, Is Dependent upon RME-1, Rab35/EPI64C, and an N-terminal Domain

(2010) Yajuan Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Connecdenn Family, Rab35 Guanine Nucleotide Exchange Factors Interfacing with the Clathrin Machinery

(2010) Andrea L. Marat et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Clearance of apoptotic cells: implications in health and disease

(2010) Michael R. Elliott et al.   JOURNAL OF CELL BIOLOGY

Regulation of exosome secretion by Rab35 and its GTPase-activating proteins TBC1D10A–C

(2010) Chieh Hsu et al.   JOURNAL OF CELL BIOLOGY

Rab35 Mediates Transport of Cdc42 and Rac1 to the Plasma Membrane during Phagocytosis

(2010) J. Shim et al.   MOLECULAR AND CELLULAR BIOLOGY

Three sorting nexins drive the degradation of apoptotic cells in response to PtdIns(3)P signaling

(2010) Nan Lu et al.   MOLECULAR BIOLOGY OF THE CELL

Identification of two evolutionarily conserved genes regulating processing of engulfed apoptotic cells

(2010) Jason M. Kinchen et al.   NATURE

Sequential action of Caenorhabditis elegans Rab GTPases regulates phagolysosome formation during apoptotic cell degradation

(2010) P. Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Far-red fluorescent tags for protein imaging in living tissues

(2009) Dmitry Shcherbo et al.   BIOCHEMICAL JOURNAL

C. elegans Rab GTPase activating protein TBC-2 promotes cell corpse degradation by regulating the small GTPase RAB-5

(2009) W. Li et al.   DEVELOPMENT

Rab35 regulates neurite outgrowth and cell shape

(2009) Julien Chevallier et al.   FEBS LETTERS

Live-Cell Imaging in Caenorhabditis elegans Reveals the Distinct Roles of Dynamin Self-Assembly and Guanosine Triphosphate Hydrolysis in the Removal of Apoptotic Cells

(2009) Bin He et al.   MOLECULAR BIOLOGY OF THE CELL

Rab GTPases as coordinators of vesicle traffic

(2009) Harald Stenmark   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Rab35 Controls Actin Bundling by Recruiting Fascin as an Effector Protein

(2009) J. Zhang et al.   SCIENCE

C. elegans Rab GTPase 2 is required for the degradation of apoptotic cells

(2008) Q. Lu et al.   DEVELOPMENT

Regulation of endocytic recycling by C. elegans Rab35 and its regulator RME-4, a coated-pit protein

(2008) Miyuki Sato et al.   EMBO JOURNAL

Rab35 and Its GAP EPI64C in T Cells Regulate Receptor Recycling and Immunological Synapse Formation

(2008) Genaro Patino-Lopez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Major Histocompatibility Complex Class II-Peptide Complexes Internalize Using a Clathrin- and Dynamin-independent Endocytosis Pathway

(2008) Even Walseng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The small GTPase Rab2 functions in the removal of apoptotic cells inCaenorhabditis elegans

(2008) Paolo M. Mangahas et al.   JOURNAL OF CELL BIOLOGY

SopB promotes phosphatidylinositol 3-phosphate formation onSalmonellavacuoles by recruiting Rab5 and Vps34

(2008) Gustavo V. Mallo et al.   JOURNAL OF CELL BIOLOGY

A pathway for phagosome maturation during engulfment of apoptotic cells

(2008) Jason M. Kinchen et al.   NATURE CELL BIOLOGY

Phagocytic Receptor CED-1 Initiates a Signaling Pathway for Degrading Engulfed Apoptotic Cells

(2008) Xiaomeng Yu et al.   PLOS BIOLOGY

Systemic lupus erythematosus in the elderly

(2007) J. Rovenský et al.   AUTOIMMUNITY REVIEWS