Genome-Wide Association Study of CSF Levels of 59 Alzheimer's Disease Candidate Proteins: Significant Associations with Proteins Involved in Amyloid Processing and Inflammation

Haplotypes Across ACE and the Risk of Alzheimer's Disease: The Three-City Study

(2017) Amélie Bruandet et al.   JOURNAL OF ALZHEIMERS DISEASE

Phosphorylated Tau-Aβ 42 Ratio as a Continuous Trait for Biomarker Discovery for Early-Stage Alzheimer’s Disease in Multiplex Immunoassay Panels of Cerebrospinal Fluid

(2014) Oscar Harari et al.   BIOLOGICAL PSYCHIATRY

Trans-Signaling Is a Dominant Mechanism for the Pathogenic Actions of Interleukin-6 in the Brain

(2014) I. L. Campbell et al.   JOURNAL OF NEUROSCIENCE

Variants in PPP3R1 and MAPT are associated with more rapid functional decline in Alzheimer's disease: The Cache County Dementia Progression Study

(2013) David Peterson et al.   Alzheimers & Dementia

Genetic analysis of quantitative phenotypes in AD and MCI: imaging, cognition and biomarkers

(2013) Li Shen et al.   Brain Imaging and Behavior

Multiethnic Meta-Analysis of Genome-Wide Association Studies in >100 000 Subjects Identifies 23 Fibrinogen-Associated Loci but No Strong Evidence of a Causal Association Between Circulating Fibrinogen and Cardiovascular Disease

(2013) Maria Sabater-Lleal et al.   CIRCULATION

Genetic variation associated with circulating monocyte count in the eMERGE Network

(2013) David R. Crosslin et al.   HUMAN MOLECULAR GENETICS

Influence of TSPO Genotype on 11C-PBR28 Standardized Uptake Values

(2013) K. K. Yoder et al.   JOURNAL OF NUCLEAR MEDICINE

Whole-exome sequencing and imaging genetics identify functional variants for rate of change in hippocampal volume in mild cognitive impairment

(2013) K Nho et al.   MOLECULAR PSYCHIATRY

Identification of functional variants from whole-exome sequencing, combined with neuroimaging genetics

(2013) K Nho et al.   MOLECULAR PSYCHIATRY

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

(2013) Jean-Charles Lambert et al.   NATURE GENETICS

GWAS of Cerebrospinal Fluid Tau Levels Identifies Risk Variants for Alzheimer’s Disease

(2013) Carlos Cruchaga et al.   NEURON

Genetic Loci Associated with Alzheimer’s Disease and Cerebrospinal Fluid Biomarkers in a Finnish Case-Control Cohort

(2013) Lyzel S. Elias-Sonnenschein et al.   PLoS One

Influence of Genetic Variation on Plasma Protein Levels in Older Adults Using a Multi-Analyte Panel

(2013) Sungeun Kim et al.   PLoS One

Mitochondrial Haplotypes Associated with Biomarkers for Alzheimer’s Disease

(2013) Perry G. Ridge et al.   PLoS One

Mechanisms of HIV Entry into the CNS: Increased Sensitivity of HIV Infected CD14+CD16+ Monocytes to CCL2 and Key Roles of CCR2, JAM-A, and ALCAM in Diapedesis

(2013) Dionna W. Williams et al.   PLoS One

Functional IL6R 358Ala Allele Impairs Classical IL-6 Receptor Signaling and Influences Risk of Diverse Inflammatory Diseases

(2013) Ricardo C. Ferreira et al.   PLoS Genetics

A Genome-Wide Association Study for Coronary Artery Disease Identifies a Novel Susceptibility Locus in the Major Histocompatibility Complex

(2012) Robert W. Davies et al.   Circulation-Cardiovascular Genetics

Annotation of functional variation in personal genomes using RegulomeDB

(2012) A. P. Boyle et al.   GENOME RESEARCH

Cerebrospinal fluid APOE levels: an endophenotype for genetic studies for Alzheimer's disease

(2012) Carlos Cruchaga et al.   HUMAN MOLECULAR GENETICS

CCL2 Is Associated with a Faster Rate of Cognitive Decline during Early Stages of Alzheimer's Disease

(2012) Karin Westin et al.   PLoS One

MultiPhen: Joint Model of Multiple Phenotypes Can Increase Discovery in GWAS

(2012) Paul F. O’Reilly et al.   PLoS One

Meta-Analysis of Genome-Wide Association Studies in >80 000 Subjects Identifies Multiple Loci for C-Reactive Protein Levels

(2011) Abbas Dehghan et al.   CIRCULATION

Functional analysis of APOE locus genetic variation implicates regional enhancers in the regulation of both TOMM40 and APOE

(2011) Lynn M Bekris et al.   JOURNAL OF HUMAN GENETICS

CC Chemokine Receptor 2 Deficiency Aggravates Cognitive Impairments and Amyloid Pathology in a Transgenic Mouse Model of Alzheimer's Disease

(2011) G. Naert et al.   JOURNAL OF NEUROSCIENCE

Identification of IL6R and chromosome 11q13.5 as risk loci for asthma

(2011) Manuel AR Ferreira et al.   LANCET

Fine Mapping of Genetic Variants in BIN1, CLU, CR1 and PICALM for Association with Cerebrospinal Fluid Biomarkers for Alzheimer's Disease

(2011) John S. K. Kauwe et al.   PLoS One

Alzheimer's Disease: The Challenge of the Second Century

(2011) D. M. Holtzman et al.   Science Translational Medicine

Update on the biomarker core of the Alzheimer's Disease Neuroimaging Initiative subjects

(2010) John Q. Trojanowski et al.   Alzheimers & Dementia

Exploration of disease mechanism in acute kidney injury using a multiplex bead array assay: a nested case–control pilot study

(2010) Orfeas Liangos et al.   BIOMARKERS

Genome-wide association reveals genetic effects on human Aβ 42 and τ protein levels in cerebrospinal fluids: a case control study

(2010) Mi-Ryung Han et al.   BMC Neurology

Interleukin-6 receptor gene polymorphisms were associated with sporadic Alzheimer's disease in Chinese Han

(2010) Min Wang et al.   BRAIN RESEARCH

The role of monocyte chemoattractant protein MCP1/CCL2 in neuroinflammatory diseases

(2010) Grégory Conductier et al.   JOURNAL OF NEUROIMMUNOLOGY

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

Genome-wide association study of CSF biomarkers A 1-42, t-tau, and p-tau181p in the ADNI cohort

(2010) S. Kim et al.   NEUROLOGY

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

(2010) K. Wang et al.   NUCLEIC ACIDS RESEARCH

A genome-wide association study identifies new loci for ACE activity: potential implications for response to ACE inhibitor

(2010) C-M Chung et al.   PHARMACOGENOMICS JOURNAL

SNPs Associated with Cerebrospinal Fluid Phospho-Tau Levels Influence Rate of Decline in Alzheimer's Disease

(2010) Carlos Cruchaga et al.   PLoS Genetics

Cerebrospinal Fluid Biomarkers and Rate of Cognitive Decline in Very Mild Dementia of the Alzheimer Type

(2009) Barbara J. Snider et al.   ARCHIVES OF NEUROLOGY

ADAM17-mediated shedding of the IL6R induces cleavage of the membrane stub by γ-secretase

(2009) Athena Chalaris et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Genome-Wide Association Scan Identifies Variants near Matrix Metalloproteinase ( MMP ) Genes on Chromosome 11q21–22 Strongly Associated With Serum MMP-1 Levels

(2009) Yu-Ching Cheng et al.   Circulation-Cardiovascular Genetics

Relationships between biomarkers in aging and dementia

(2009) W. J. Jagust et al.   NEUROLOGY

An age effect on the association of common variants of ACE with Alzheimer's disease

(2009) Nicole Helbecque et al.   NEUROSCIENCE LETTERS

CALHM1 P86L polymorphism does not alter amyloid-β or tau in cerebrospinal fluid

(2009) Vilmantas Giedraitis et al.   NEUROSCIENCE LETTERS

CCL2 Accelerates Microglia-Mediated Aβ Oligomer Formation and Progression of Neurocognitive Dysfunction

(2009) Tomomi Kiyota et al.   PLoS One

Missing data imputation and haplotype phase inference for genome-wide association studies

(2008) Sharon R. Browning   HUMAN GENETICS

Alzheimer’s disease risk variants show association with cerebrospinal fluid amyloid beta

(2008) John S. K. Kauwe et al.   NEUROGENETICS

Variation in MAPT is associated with cerebrospinal fluid tau levels in the presence of amyloid-beta deposition

(2008) J. S. K. Kauwe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Genome-Wide Association Study Identifies Protein Quantitative Trait Loci (pQTLs)

(2008) David Melzer et al.   PLoS Genetics

Matrix metalloproteinase 3 haplotypes and dementia and Alzheimer's disease

(2007) Christiane Reitz et al.   NEUROBIOLOGY OF AGING