Essential Genetic Interactors of SIR2 Required for Spatial Sequestration and Asymmetrical Inheritance of Protein Aggregates

Enhancing protein disaggregation restores proteasome activity in aged cells

(2016) Veronica Andersson et al.   Aging-US

Opposing roles of Ubp3-dependent deubiquitination regulate replicative life span and heat resistance

(2014) D. Oling et al.   EMBO JOURNAL

Actin Dynamics Affect Mitochondrial Quality Control and Aging in Budding Yeast

(2013) Ryo Higuchi et al.   CURRENT BIOLOGY

The asymmetric segregation of damaged proteins is stem cell–type dependent

(2013) Mary Rose Bufalino et al.   JOURNAL OF CELL BIOLOGY

Spatial sequestration of misfolded proteins by a dynamic chaperone pathway enhances cellular fitness during stress

(2013) Stéphanie Escusa-Toret et al.   NATURE CELL BIOLOGY

SNCA (α-synuclein)-induced toxicity in yeast cells is dependent on Sir2-mediated mitophagy

(2012) Belém Sampaio-Marques et al.   Autophagy

Aggresome formation and segregation of inclusions influence toxicity of α-synuclein and synphilin-1 in yeast

(2012) Erwin Swinnen et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Molecular chaperones and stress-inducible protein-sorting factors coordinate the spatiotemporal distribution of protein aggregates

(2012) Liliana Malinovska et al.   MOLECULAR BIOLOGY OF THE CELL

Confinement to Organelle-Associated Inclusion Structures Mediates Asymmetric Inheritance of Aggregated Protein in Budding Yeast

(2012) Rachel Spokoini et al.   Cell Reports

Motility and Segregation of Hsp104-Associated Protein Aggregates in Budding Yeast

(2011) Chuankai Zhou et al.   CELL

Segregation of Protein Aggregates Involves Actin and the Polarity Machinery

(2011) Beidong Liu et al.   CELL

Hsp42 is required for sequestration of protein aggregates into deposition sites inSaccharomyces cerevisiae

(2011) Sebastian Specht et al.   JOURNAL OF CELL BIOLOGY

Prion Induction by the Short-Lived, Stress-Induced Protein Lsb2 Is Regulated by Ubiquitination and Association with the Actin Cytoskeleton

(2011) Tatiana A. Chernova et al.   MOLECULAR CELL

Systematic exploration of essential yeast gene function with temperature-sensitive mutants

(2011) Zhijian Li et al.   NATURE BIOTECHNOLOGY

Super-resolution microscopy for nanosensing

(2011) James A. Galbraith et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Sir2-dependent asymmetric segregation of damaged proteins in ubp10 null mutants is independent of genomic silencing

(2010) Ivan Orlandi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The Polarisome Is Required for Segregation and Retrograde Transport of Protein Aggregates

(2010) Beidong Liu et al.   CELL

Breaking the Diffraction Barrier: Super-Resolution Imaging of Cells

(2010) Bo Huang et al.   CELL

Hos1 Deacetylates Smc3 to Close the Cohesin Acetylation Cycle

(2010) Vanessa Borges et al.   MOLECULAR CELL

Synphilin-1 Enhances α-Synuclein Aggregation in Yeast and Contributes to Cellular Stress and Cell Death in a Sir2-Dependent Manner

(2010) Sabrina Büttner et al.   PLoS One

The Genetic Landscape of a Cell

(2010) M. Costanzo et al.   SCIENCE

The Yeast AAA+ Chaperone Hsp104 Is Part of a Network That Links the Actin Cytoskeleton with the Inheritance of Damaged Proteins

(2009) P. Tessarz et al.   MOLECULAR AND CELLULAR BIOLOGY

Histone H4 lysine 16 acetylation regulates cellular lifespan

(2009) Weiwei Dang et al.   NATURE

The interaction network of the chaperonin CCT

(2008) Carien Dekker et al.   EMBO JOURNAL

Misfolded proteins partition between two distinct quality control compartments

(2008) Daniel Kaganovich et al.   NATURE

Selective benefits of damage partitioning in unicellular systems and its effects on aging

(2008) N. Erjavec et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDP-43 aggregation and cellular toxicity

(2008) B. S. Johnson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Subdiffraction Multicolor Imaging of the Nuclear Periphery with 3D Structured Illumination Microscopy

(2008) L. Schermelleh et al.   SCIENCE