Synphilin-1 Enhances α-Synuclein Aggregation in Yeast and Contributes to Cellular Stress and Cell Death in a Sir2-Dependent Manner

The life span-prolonging effect of Sirtuin-1 is mediated by autophagy

(2010) Eugenia Morselli et al.   Autophagy

The Polarisome Is Required for Segregation and Retrograde Transport of Protein Aggregates

(2010) Beidong Liu et al.   CELL

Synphilin-1 attenuates neuronal degeneration in the A53T  -synuclein transgenic mouse model

(2010) W. W. Smith et al.   HUMAN MOLECULAR GENETICS

The molecular mechanism of mitochondria autophagy in yeast

(2010) Tomotake Kanki et al.   MOLECULAR MICROBIOLOGY

Can autophagy promote longevity?

(2010) Frank Madeo et al.   NATURE CELL BIOLOGY

Regulation of macroautophagy in Saccharomyces cerevisiae

(2010) Yuko Inoue et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Conditions of endoplasmic reticulum stress stimulate lipid droplet formation inSaccharomyces cerevisiae

(2009) Weihua Fei et al.   BIOCHEMICAL JOURNAL

Yeast unfolds the road map toward α-synuclein-induced cell death

(2009) V Franssens et al.   CELL DEATH AND DIFFERENTIATION

SIRT1: Regulation of longevity via autophagy

(2009) Antero Salminen et al.   CELLULAR SIGNALLING

Interaction with synphilin-1 promotes inclusion formation of α-synuclein: mechanistic insights and pathological implication

(2009) Yuan-Yuan Xie et al.   FASEB JOURNAL

The First N-terminal Amino Acids of α-Synuclein Are Essential for α-Helical Structure Formation In Vitro and Membrane Binding in Yeast

(2009) Katherina Vamvaca et al.   JOURNAL OF MOLECULAR BIOLOGY

Transgenic overexpression of the alpha-synuclein interacting protein synphilin-1 leads to behavioral and neuropathological alterations in mice

(2009) Silke Nuber et al.   NEUROGENETICS

Protein folding diseases and neurodegeneration: Lessons learned from yeast

(2008) Joris Winderickx et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Phosphorylation, lipid raft interaction and traffic of α-synuclein in a yeast model for Parkinson

(2008) Piotr Zabrocki et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Genetic association study of synphilin-1in idiopathic Parkinson's disease

(2008) Ronny Myhre et al.   BMC Medical Genetics

Abnormal proteins can form aggresome in yeast: aggresome-targeting signals and components of the machinery

(2008) Yan Wang et al.   FASEB JOURNAL

Autophagy-mediated clearance of aggresomes is not a universal phenomenon

(2008) Esther S.P. Wong et al.   HUMAN MOLECULAR GENETICS

Triggering Aggresome Formation

(2008) Nava Zaarur et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional Mitochondria Are Required for α-Synuclein Toxicity in Aging Yeast

(2008) Sabrina Büttner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Aggregate formation and toxicity by wild-type and R621C synphilin-1 in the nigrostriatal system of mice using adenoviral vectors

(2008) Antje Krenz et al.   JOURNAL OF NEUROCHEMISTRY

Synphilin-1 transgenic mice exhibit mild motor impairments

(2008) Hong-Guo Jin et al.   NEUROSCIENCE LETTERS

SIRT1 and neuronal diseases

(2007) Bor Luen Tang et al.   MOLECULAR ASPECTS OF MEDICINE