Aberrant Autolysosomal Regulation Is Linked to The Induction of Embryonic Senescence: Differential Roles of Beclin 1 and p53 in Vertebrate Spns1 Deficiency
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Title
Aberrant Autolysosomal Regulation Is Linked to The Induction of Embryonic Senescence: Differential Roles of Beclin 1 and p53 in Vertebrate Spns1 Deficiency
Authors
Keywords
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Journal
PLoS Genetics
Volume 10, Issue 6, Pages e1004409
Publisher
Public Library of Science (PLoS)
Online
2014-06-27
DOI
10.1371/journal.pgen.1004409
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- The essence of senescence
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- (2009) Karen H. Vousden et al. CELL
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