PINK1 as a molecular checkpoint in the maintenance of mitochondrial function and integrity
Published 2012 View Full Article
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Title
PINK1 as a molecular checkpoint in the maintenance of mitochondrial function and integrity
Authors
Keywords
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Journal
MOLECULES AND CELLS
Volume 34, Issue 1, Pages 7-13
Publisher
Springer Nature
Online
2012-05-20
DOI
10.1007/s10059-012-0100-8
References
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Related references
Note: Only part of the references are listed.- Silent Information Regulator 2 (Sir2) and Forkhead Box O (FOXO) Complement Mitochondrial Dysfunction and Dopaminergic Neuron Loss inDrosophilaPTEN-induced Kinase 1 (PINK1) Null Mutant
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- Parkinson's Disease–Associated Kinase PINK1 Regulates Miro Protein Level and Axonal Transport of Mitochondria
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- PINK1 and Parkin Target Miro for Phosphorylation and Degradation to Arrest Mitochondrial Motility
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- Functional alteration of PARL contributes to mitochondrial dysregulation in Parkinson's disease
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- Broad activation of the ubiquitin–proteasome system by Parkin is critical for mitophagy
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- PTEN-inducible kinase 1 (PINK1)/Park6 is indispensable for normal heart function
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- p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both
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- Impaired dopaminergic neuron development and locomotor function in zebrafish with loss ofpink1function
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- Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy
- (2010) Matthew E. Gegg et al. HUMAN MOLECULAR GENETICS
- PINK1 cleavage at position A103 by the mitochondrial protease PARL
- (2010) Emma Deas et al. HUMAN MOLECULAR GENETICS
- Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics
- (2010) I. Irrcher et al. HUMAN MOLECULAR GENETICS
- DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy
- (2010) Kelly Jean Thomas et al. HUMAN MOLECULAR GENETICS
- Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin
- (2010) Atsushi Tanaka et al. JOURNAL OF CELL BIOLOGY
- Disease-causing mutations in Parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy
- (2010) Joo-Yong Lee et al. JOURNAL OF CELL BIOLOGY
- Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL
- (2010) Seok Min Jin et al. JOURNAL OF CELL BIOLOGY
- PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
- (2010) Noriyuki Matsuda et al. JOURNAL OF CELL BIOLOGY
- Parkin Suppresses c-Jun N-terminal kinase-induced cell death via transriptional regulation in Drosophila
- (2010) Soojin Hwang et al. MOLECULES AND CELLS
- PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
- (2010) Sven Geisler et al. NATURE CELL BIOLOGY
- Dopaminergic cell damage and vulnerability to MPTP in Pink1 knockdown zebrafish
- (2010) Ville Sallinen et al. NEUROBIOLOGY OF DISEASE
- Drosophila Parkin requires PINK1 for mitochondrial translocation and ubiquitinates Mitofusin
- (2010) E. Ziviani et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- DJ-1 is critical for mitochondrial function and rescues PINK1 loss of function
- (2010) L.-Y. Hao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin
- (2010) Derek P. Narendra et al. PLOS BIOLOGY
- The Loss of PGAM5 Suppresses the Mitochondrial Degeneration Caused by Inactivation of PINK1 in Drosophila
- (2010) Yuzuru Imai et al. PLoS Genetics
- The coordination of nuclear and mitochondrial communication during aging and calorie restriction
- (2009) Lydia W.S. Finley et al. AGEING RESEARCH REVIEWS
- 4E-BP Extends Lifespan upon Dietary Restriction by Enhancing Mitochondrial Activity in Drosophila
- (2009) Brian M. Zid et al. CELL
- Leucine-rich repeat kinase 2 interacts with Parkin, DJ-1 and PINK-1 in a Drosophila melanogaster model of Parkinson's disease
- (2009) K. Venderova et al. HUMAN MOLECULAR GENETICS
- Caenorhabditits elegansLRK-1 and PINK-1 Act Antagonistically in Stress Response and Neurite Outgrowth
- (2009) Julia Sämann et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Parkinson disease-associated protein kinase LRRK2 exhibits MAPKKK activity and phosphorylates MKK3/6 and MKK4/7,in vitro
- (2009) Christian Johannes Gloeckner et al. JOURNAL OF NEUROCHEMISTRY
- Loss-of-Function Analysis Suggests That Omi/HtrA2 Is Not an Essential Component of the pink1/parkin Pathway In Vivo
- (2009) J. Yun et al. JOURNAL OF NEUROSCIENCE
- Rapamycin activation of 4E-BP prevents parkinsonian dopaminergic neuron loss
- (2009) Luke S Tain et al. NATURE NEUROSCIENCE
- PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
- (2009) C. Vives-Bauza et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PINK1 controls mitochondrial localization of Parkin through direct phosphorylation
- (2008) Yongsung Kim et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The PINK1–Parkin pathway is involved in the regulation of mitochondrial remodeling process
- (2008) Jeehye Park et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
- (2008) Derek Narendra et al. JOURNAL OF CELL BIOLOGY
- Negative regulation of the deacetylase SIRT1 by DBC1
- (2008) Wenhui Zhao et al. NATURE
- DBC1 is a negative regulator of SIRT1
- (2008) Ja-Eun Kim et al. NATURE
- Correction for Yang et al., Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery
- (2008) PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cytoplasmic Pink1 activity protects neurons from dopaminergic neurotoxin MPTP
- (2008) M. E. Haque et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress
- (2008) C. A. Gautier et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The kinase domain of mitochondrial PINK1 faces the cytoplasm
- (2008) C. Zhou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The PINK1/Parkin pathway regulates mitochondrial morphology
- (2008) A. C. Poole et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila
- (2008) H. Deng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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