Informed Conditioning on Clinical Covariates Increases Power in Case-Control Association Studies

Genetic Variants on 15q25.1, Smoking, and Lung Cancer: An Assessment of Mediation and Interaction

(2012) Tyler J. VanderWeele et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Analysis of case–control association studies with known risk variants

(2012) Noah Zaitlen et al.   BIOINFORMATICS

Link Functions in Multi-Locus Genetic Models: Implications for Testing, Prediction, and Interpretation

(2012) David Clayton   GENETIC EPIDEMIOLOGY

Including known covariates can reduce power to detect genetic effects in case-control studies

(2012) Matti Pirinen et al.   NATURE GENETICS

Association analyses identify multiple new lung cancer susceptibility loci and their interactions with smoking in the Chinese population

(2012) Jing Dong et al.   NATURE GENETICS

Stratifying Type 2 Diabetes Cases by BMI Identifies Genetic Risk Variants in LAMA1 and Enrichment for Risk Variants in Lean Compared to Obese Cases

(2012) John R. B. Perry et al.   PLoS Genetics

Estimating Missing Heritability for Disease from Genome-wide Association Studies

(2011) Sang Hong Lee et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Interactions Between Genetic Variants and Breast Cancer Risk Factors in the Breast and Prostate Cancer Cohort Consortium

(2011) D. Campa et al.   JNCI-Journal of the National Cancer Institute

A rare penetrant mutation in CFH confers high risk of age-related macular degeneration

(2011) Soumya Raychaudhuri et al.   NATURE GENETICS

Identification of low-frequency variants associated with gout and serum uric acid levels

(2011) Patrick Sulem et al.   NATURE GENETICS

Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study

(2011) Zsofia Kote-Jarai et al.   NATURE GENETICS

A rare variant in MYH6 is associated with high risk of sick sinus syndrome

(2011) Hilma Holm et al.   NATURE GENETICS

Characterizing Associations and SNP-Environment Interactions for GWAS-Identified Prostate Cancer Risk Markers—Results from BPC3

(2011) Sara Lindstrom et al.   PLoS One

Genome-Wide Gene-Environment Study Identifies Glutamate Receptor Gene GRIN2A as a Parkinson's Disease Modifier Gene via Interaction with Coffee

(2011) Taye H. Hamza et al.   PLoS Genetics

A Common Variant at Chromosome 9P21.3 Is Associated With Age of Onset of Coronary Disease but Not Subsequent Mortality

(2010) Katrina L. Ellis et al.   Circulation-Cardiovascular Genetics

Chipping away at the genetics of smoking behavior

(2010) Christopher I Amos et al.   NATURE GENETICS

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

(2010) Benjamin F Voight et al.   NATURE GENETICS

New approaches to population stratification in genome-wide association studies

(2010) Alkes L. Price et al.   NATURE REVIEWS GENETICS

Gene–environment-wide association studies: emerging approaches

(2010) Duncan Thomas   NATURE REVIEWS GENETICS

Association of Trypanolytic ApoL1 Variants with Kidney Disease in African Americans

(2010) G. Genovese et al.   SCIENCE

A Unifying Framework for Evaluating the Predictive Power of Genetic Variants Based on the Level of Heritability Explained

(2010) Hon-Cheong So et al.   PLoS Genetics

The Genetic Interpretation of Area under the ROC Curve in Genomic Profiling

(2010) Naomi R. Wray et al.   PLoS Genetics

Common genetic variants on 5p15.33 contribute to risk of lung adenocarcinoma in a Chinese population

(2009) Guangfu Jin et al.   CARCINOGENESIS

Genome-wide association scans for secondary traits using case-control samples

(2009) Genevieve M. Monsees et al.   GENETIC EPIDEMIOLOGY

Common variants at five new loci associated with early-onset inflammatory bowel disease

(2009) Marcin Imielinski et al.   NATURE GENETICS

Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants

(2009) Sekar Kathiresan et al.   NATURE GENETICS

Power of deep, all-exon resequencing for discovery of human trait genes

(2009) G. V. Kryukov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A comprehensive analysis of phase I and phase II metabolism gene polymorphisms and risk of non-small cell lung cancer in smokers

(2008) Shanbeh Zienolddiny et al.   CARCINOGENESIS

When the smoke clears ...

(2008) Stephen J. Chanock et al.   NATURE

Data and Theory Point to Mainly Additive Genetic Variance for Complex Traits

(2008) William G. Hill et al.   PLoS Genetics

Rationale, Design, and Methodology of the Women's Genome Health Study: A Genome-Wide Association Study of More Than 25 000 Initially Healthy American Women

(2007) P. M Ridker et al.   CLINICAL CHEMISTRY