Genetic Variants on 15q25.1, Smoking, and Lung Cancer: An Assessment of Mediation and Interaction

Odds Ratios for Mediation Analysis for a Dichotomous Outcome

(2010) T. J. VanderWeele et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Mediating effects of smoking and chronic obstructive pulmonary disease on the relation between the CHRNA5-A3 genetic locus and lung cancer risk

(2010) Jian Wang et al.   CANCER

Bias Formulas for Sensitivity Analysis for Direct and Indirect Effects

(2010) Tyler J. VanderWeele   EPIDEMIOLOGY

Commentary: Gene-environment interactions and smoking-related cancers

(2010) T. E. Thorgeirsson et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Replication of Lung Cancer Susceptibility Loci at Chromosomes 15q25, 5p15, and 6p21: A Pooled Analysis From the International Lung Cancer Consortium

(2010) Therese Truong et al.   JNCI-Journal of the National Cancer Institute

Genetic variants and risk of lung cancer in never smokers: a genome-wide association study

(2010) Yafei Li et al.   LANCET ONCOLOGY

Sequence variants at CHRNB3–CHRNA6 and CYP2A6 affect smoking behavior

(2010) Thorgeir E Thorgeirsson et al.   NATURE GENETICS

Genome-wide meta-analyses identify multiple loci associated with smoking behavior

(2010)   NATURE GENETICS

Meta-analysis and imputation refines the association of 15q25 with smoking quantity

(2010) Jason Z Liu et al.   NATURE GENETICS

Multiple Independent Loci at Chromosome 15q25.1 Affect Smoking Quantity: a Meta-Analysis and Comparison with Lung Cancer and COPD

(2010) Nancy L. Saccone et al.   PLoS Genetics

Association between a 15q25 gene variant, smoking quantity and tobacco-related cancers among 17 000 individuals

(2009) Esther H Lips et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Variants in Nicotinic Receptors and Risk for Nicotine Dependence

(2008) Laura Jean Bierut et al.   AMERICAN JOURNAL OF PSYCHIATRY

Nicotinic Receptor Gene Variants Influence Susceptibility to Heavy Smoking

(2008) V. L. Stevens et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Smokers with the CHRNA Lung Cancer-Associated Variants Are Exposed to Higher Levels of Nicotine Equivalents and a Carcinogenic Tobacco-Specific Nitrosamine

(2008) L. Le Marchand et al.   CANCER RESEARCH

Intermediacy and Gene–Environment Interaction: The Example of CHRNA5-A3 Region, Smoking, Nicotine Dependence, and Lung Cancer

(2008) Sholom Wacholder et al.   JNCI-Journal of the National Cancer Institute

The CHRNA5-A3 Region on Chromosome 15q24-25.1 Is a Risk Factor Both for Nicotine Dependence and for Lung Cancer

(2008) Margaret R. Spitz et al.   JNCI-Journal of the National Cancer Institute

α-5/α-3 nicotinic receptor subunit alleles increase risk for heavy smoking

(2008) W Berrettini et al.   MOLECULAR PSYCHIATRY

Multiple roles of nicotine on cell proliferation and inhibition of apoptosis: Implications on lung carcinogenesis

(2008) A CATASSI et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

When the smoke clears ...

(2008) Stephen J. Chanock et al.   NATURE

A variant associated with nicotine dependence, lung cancer and peripheral arterial disease

(2008) Thorgeir E. Thorgeirsson et al.   NATURE

A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25

(2008) Rayjean J. Hung et al.   NATURE

Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1

(2008) Christopher I Amos et al.   NATURE GENETICS

Nicotinic acetylcholine receptors in cancer: multiple roles in proliferation and inhibition of apoptosis

(2008) Richard D. Egleton et al.   TRENDS IN PHARMACOLOGICAL SCIENCES