Impact of Dimensionality and Network Disruption on Microrheology of Cancer Cells in 3D Environments

Probing the Stochastic, Motor-Driven Properties of the Cytoplasm Using Force Spectrum Microscopy

(2014) Ming Guo et al.   CELL

Generation of 3D functional microvascular networks with human mesenchymal stem cells in microfluidic systems

(2014) Jessie S. Jeon et al.   Integrative Biology

Mechanotransduction of fluid stresses governs 3D cell migration

(2014) W. J. Polacheck et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Guidance of Cell Migration by Substrate Dimension

(2013) Stephanie S. Chang et al.   BIOPHYSICAL JOURNAL

Dimensions in cell migration

(2013) Andrew D Doyle et al.   CURRENT OPINION IN CELL BIOLOGY

A serial micropipette microfluidic device with applications to cancer cell repeated deformation studies

(2013) Michael Mak et al.   Integrative Biology

Mechanisms of tumor cell extravasation in an in vitro microvascular network platform

(2013) Michelle B. Chen et al.   Integrative Biology

Physical limits of cell migration: Control by ECM space and nuclear deformation and tuning by proteolysis and traction force

(2013) Katarina Wolf et al.   JOURNAL OF CELL BIOLOGY

From Structure to Function: Mitochondrial Morphology, Motion and Shaping in Vascular Smooth Muscle

(2013) John G. McCarron et al.   JOURNAL OF VASCULAR RESEARCH

Mechanical decision trees for investigating and modulating single-cell cancer invasion dynamics

(2013) Michael Mak et al.   LAB ON A CHIP

Molecular motors robustly drive active gels to a critically connected state

(2013) José Alvarado et al.   Nature Physics

Characterizing deformability and surface friction of cancer cells

(2013) S. Byun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Elucidating mechanical transition effects of invading cancer cells with a subnucleus-scaled microfluidic serial dimensional modulation device

(2012) Michael Mak et al.   LAB ON A CHIP

Dual-objective STORM reveals three-dimensional filament organization in the actin cytoskeleton

(2012) Ke Xu et al.   NATURE METHODS

High-throughput ballistic injection nanorheology to measure cell mechanics

(2012) Pei-Hsun Wu et al.   Nature Protocols

Microfluidic assay for simultaneous culture of multiple cell types on surfaces or within hydrogels

(2012) Yoojin Shin et al.   Nature Protocols

Stochastic Force Generation by Small Ensembles of Myosin II Motors

(2012) Thorsten Erdmann et al.   PHYSICAL REVIEW LETTERS

Cellular Traction Stresses Increase with Increasing Metastatic Potential

(2012) Casey M. Kraning-Rush et al.   PLoS One

Cell Stiffness Is a Biomarker of the Metastatic Potential of Ovarian Cancer Cells

(2012) Wenwei Xu et al.   PLoS One

Dynamic Mechanisms of Cell Rigidity Sensing: Insights from a Computational Model of Actomyosin Networks

(2012) Carlos Borau et al.   PLoS One

Hydrodynamic stretching of single cells for large population mechanical phenotyping

(2012) D. R. Gossett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Three-dimensional microfluidic model for tumor cell intravasation and endothelial barrier function

(2012) I. K. Zervantonakis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell Shape and Substrate Rigidity Both Regulate Cell Stiffness

(2011) Shang-You Tee et al.   BIOPHYSICAL JOURNAL

A microfabricated deformability-based flow cytometer with application to malaria

(2011) Hansen Bow et al.   LAB ON A CHIP

Interstitial flow influences direction of tumor cell migration through competing mechanisms

(2011) W. J. Polacheck et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fluid Mechanics of Microrheology

(2010) Todd M. Squires et al.   Annual Review of Fluid Mechanics

Cancer Cell Stiffness: Integrated Roles of Three-Dimensional Matrix Stiffness and Transforming Potential

(2010) Erin L. Baker et al.   BIOPHYSICAL JOURNAL

A distinctive role for focal adhesion proteins in three-dimensional cell motility

(2010) Stephanie I. Fraley et al.   NATURE CELL BIOLOGY

Metastasis: tumor cells becoming MENAcing

(2010) Frank Gertler et al.   TRENDS IN CELL BIOLOGY

Particle-Tracking Microrheology of Living Cells: Principles and Applications

(2009) Denis Wirtz   Annual Review of Biophysics

Extracellular Matrix Stiffness and Architecture Govern Intracellular Rheology in Cancer

(2009) Erin L. Baker et al.   BIOPHYSICAL JOURNAL

Vascular Smooth Muscle Cell Durotaxis Depends on Substrate Stiffness Gradient Strength

(2009) Brett C. Isenberg et al.   BIOPHYSICAL JOURNAL

Mechanics, malignancy, and metastasis: The force journey of a tumor cell

(2009) Sanjay Kumar et al.   CANCER AND METASTASIS REVIEWS

The Mechanics and Fluctuation Spectrum of Active Gels†

(2009) Alex J. Levine et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Microrheology of Microtubule Solutions and Actin-Microtubule Composite Networks

(2009) Vincent Pelletier et al.   PHYSICAL REVIEW LETTERS

Actin polymerization driven mitochondrial transport in mating S. cerevisiae

(2009) E. N. Senning et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microfabricated tissue gauges to measure and manipulate forces from 3D microtissues

(2009) W. R. Legant et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Computational Analysis of Viscoelastic Properties of Crosslinked Actin Networks

(2009) Taeyoon Kim et al.   PLoS Computational Biology

Contact Guidance Mediated Three-Dimensional Cell Migration is Regulated by Rho/ROCK-Dependent Matrix Reorganization

(2008) Paolo P. Provenzano et al.   BIOPHYSICAL JOURNAL

Intracellular Microrheology of Motile Amoeba proteus

(2008) Salman S. Rogers et al.   BIOPHYSICAL JOURNAL

Cell migration into scaffolds under co-culture conditions in a microfluidic platform

(2008) Seok Chung et al.   LAB ON A CHIP

Out-of-Equilibrium Microrheology inside Living Cells

(2008) Claire Wilhelm   PHYSICAL REVIEW LETTERS

Anisotropic rheology and directional mechanotransduction in vascular endothelial cells

(2008) J. C. del Alamo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA