Integrative Modelling of the Influence of MAPK Network on Cancer Cell Fate Decision

Dynamical modeling and analysis of large cellular regulatory networks

(2013) D. Bérenguier et al.   CHAOS

Dynamics of p53 and NF-κB regulation in response to DNA damage and identification of target proteins suitable for therapeutic intervention

(2012) Rainer Poltz et al.   BMC Systems Biology

Continuous time boolean modeling for biological signaling: application of Gillespie algorithm

(2012) Gautier Stoll et al.   BMC Systems Biology

Dual specificity phosphatases 10 and 16 are positive regulators of EGF-stimulated ERK activity: Indirect regulation of ERK signals by JNK/p38 selective MAPK phosphatases

(2012) Ann R. Finch et al.   CELLULAR SIGNALLING

Targeting the MAPK–RAS–RAF signaling pathway in cancer therapy

(2012) Libero Santarpia et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Oncogenic FGFR3 gene fusions in bladder cancer

(2012) Sarah V. Williams et al.   HUMAN MOLECULAR GENETICS

Deregulation of Rab and Rab Effector Genes in Bladder Cancer

(2012) Joel R. Ho et al.   PLoS One

Modeling mechanistic biological networks: An advanced Boolean approach

(2011) T. Handorf et al.   BIOINFORMATICS

Novel mitogen-activated protein kinase kinase inhibitors

(2011) Mark S Chapman et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Sixteen years and counting: The current understanding of fibroblast growth factor receptor 3 (FGFR3) signaling in skeletal dysplasias

(2011) Silvie Foldynova-Trantirkova et al.   HUMAN MUTATION

A Dynamical Systems Model for Combinatorial Cancer Therapy Enhances Oncolytic Adenovirus Efficacy by MEK-Inhibition

(2011) Neda Bagheri et al.   PLoS Computational Biology

Targeting the MAPK pathway in melanoma: Why some approaches succeed and other fail

(2010) Gajanan S. Inamdar et al.   BIOCHEMICAL PHARMACOLOGY

The MAPK cascades: Signaling components, nuclear roles and mechanisms of nuclear translocation

(2010) Alexander Plotnikov et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The role of MAP kinases and MAP kinase phosphatase-1 in resistance to breast cancer treatment

(2010) Kelly K. Haagenson et al.   CANCER AND METASTASIS REVIEWS

Systemic therapy of metastatic bladder cancer in the molecular era: current status and future promise

(2010) Ioannis Zachos et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Molecular targeted therapy for patients with melanoma: the promise of MAPK pathway inhibition and beyond

(2010) Ryan J Sullivan et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Dynamically consistent reduction of logical regulatory graphs

(2010) Aurélien Naldi et al.   THEORETICAL COMPUTER SCIENCE

Mathematical Modelling of Cell-Fate Decision in Response to Death Receptor Engagement

(2010) Laurence Calzone et al.   PLoS Computational Biology

Logical modelling of regulatory networks with GINsim 2.3

(2009) A. Naldi et al.   BIOSYSTEMS

Computational modelling of cancerous mutations in the EGFR/ERK signalling pathway

(2009) Richard J Orton et al.   BMC Systems Biology

Targeting the RAF–MEK–ERK pathway in cancer therapy

(2009) Clara Montagut et al.   CANCER LETTERS

Mechanism of TGF-β signaling to growth arrest, apoptosis, and epithelial–mesenchymal transition

(2009) Carl-Henrik Heldin et al.   CURRENT OPINION IN CELL BIOLOGY

The p38 MAPK inhibitors for the treatment of inflammatory diseases and cancer

(2009) Hae-Young Yong et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Targeting MAPK (Ras/ERK) and PI3K/Akt pathways in pituitary tumorigenesis

(2009) Mehtap Cakir et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

The subcellular localization of MEK and ERK—A novel nuclear translocation signal (NTS) paves a way to the nucleus

(2009) Eldar Zehorai et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Internal coarse-graining of molecular systems

(2009) J. Feret et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Logic of EGFR/ErbB Signaling: Theoretical Properties and Analysis of High-Throughput Data

(2009) Regina Samaga et al.   PLoS Computational Biology

Graphic requirements for multistability and attractive cycles in a Boolean dynamical framework

(2008) Élisabeth Remy et al.   ADVANCES IN APPLIED MATHEMATICS

Molecular Pathogenesis and Diagnostics of Bladder Cancer

(2008) Anirban P. Mitra et al.   Annual Review of Pathology-Mechanisms of Disease

The complexity of mitogen-activated protein kinases (MAPKs) made simple

(2008) M. Krishna et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Therapeutic strategies for inhibiting oncogenic BRAF signaling

(2008) Ensar Halilovic et al.   CURRENT OPINION IN PHARMACOLOGY

CellDesigner 3.5: A Versatile Modeling Tool for Biochemical Networks

(2008) A. Funahashi et al.   PROCEEDINGS OF THE IEEE

Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival

(2007) Melissa R. Junttila et al.   FASEB JOURNAL