Sixteen years and counting: The current understanding of fibroblast growth factor receptor 3 (FGFR3) signaling in skeletal dysplasias

Fibroblast Growth Factor Receptor 3 (FGFR3) Is a Strong Heat Shock Protein 90 (Hsp90) Client

(2011) Melanie B. Laederich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Organization of the Indian hedgehog – parathyroid hormone-related protein system in the postnatal growth plate

(2011) Michael Chau et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

FGFR3 signaling induces a reversible senescence phenotype in chondrocytes similar to oncogene-induced premature senescence

(2010) Pavel Krejci et al.   BONE

New Molecular and Biological Mechanism of Antitumor Activities of KW-2478, a Novel Nonansamycin Heat Shock Protein 90 Inhibitor, in Multiple Myeloma Cells

(2010) T. Nakashima et al.   CLINICAL CANCER RESEARCH

Down-modulation of cancer targets using locked nucleic acid (LNA)-based antisense oligonucleotides without transfection

(2010) Y Zhang et al.   GENE THERAPY

NF449 Is a Novel Inhibitor of Fibroblast Growth Factor Receptor 3 (FGFR3) Signaling Active in Chondrocytes and Multiple Myeloma Cells

(2010) Pavel Krejci et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetic inactivation of ERK1 and ERK2 in chondrocytes promotes bone growth and enlarges the spinal canal

(2010) Arjun Sebastian et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

The novel JAK inhibitor AZD1480 blocks STAT3 and FGFR3 signaling, resulting in suppression of human myeloma cell growth and survival

(2010) A Scuto et al.   LEUKEMIA

Review of the recently defined molecular mechanisms underlying thanatophoric dysplasia and their potential therapeutic implications for achondroplasia

(2009) María Luisa Martínez-Frías et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Antibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in mice

(2009) Jing Qing et al.   JOURNAL OF CLINICAL INVESTIGATION

Activating mutations in FGFR3 and HRAS reveal a shared genetic origin for congenital disorders and testicular tumors

(2009) Anne Goriely et al.   NATURE GENETICS

The population-based prevalence of achondroplasia and thanatophoric dysplasia in selected regions of the US

(2008) D.K. Waller et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Regulation of articular chondrocyte proliferation and differentiation by indian hedgehog and parathyroid hormone-related protein in mice

(2008) Xuesong Chen et al.   ARTHRITIS AND RHEUMATISM

Achondroplasia

(2008) Geneviève Baujat et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

Nordihydroguaiaretic Acid Inhibits an Activated Fibroblast Growth Factor Receptor 3 Mutant and Blocks Downstream Signaling in Multiple Myeloma Cells

(2008) A. N. Meyer et al.   CANCER RESEARCH

Sprouty 2 disturbs FGFR3 degradation in thanatophoric dysplasia type II: A severe form of human achondroplasia

(2008) Changsheng Guo et al.   CELLULAR SIGNALLING

Fibroblast growth factor inhibits interferon γ-STAT1 and interleukin 6-STAT3 signaling in chondrocytes

(2008) P KREJCI et al.   CELLULAR SIGNALLING

FGFR3 promotes synchondrosis closure and fusion of ossification centers through the MAPK pathway

(2008) T. Matsushita et al.   HUMAN MOLECULAR GENETICS

FGFR3-related dwarfism and cell signaling

(2008) Daisuke Harada et al.   JOURNAL OF BONE AND MINERAL METABOLISM

STAT1 and STAT3 do not participate in FGF-mediated growth arrest in chondrocytes

(2008) P. Krejci et al.   JOURNAL OF CELL SCIENCE

Roles of Wnt signalling in bone growth, remodelling, skeletal disorders and fracture repair

(2008) Carmen E. Macsai et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Analysis of STAT1 Activation by Six FGFR3 Mutants Associated with Skeletal Dysplasia Undermines Dominant Role of STAT1 in FGFR3 Signaling in Cartilage

(2008) Pavel Krejci et al.   PLoS One

PP2A-Mediated Dephosphorylation of p107 Plays a Critical Role in Chondrocyte Cell Cycle Arrest by FGF

(2008) Victoria Kolupaeva et al.   PLoS One