Synergistic effects of TOR and proteasome pathways on the yeast transcriptome and cell growth

Ubiquitin and Proteasomes in Transcription

(2012) Fuqiang Geng et al.   Annual Review of Biochemistry

Cap-dependent mRNA translation and the ubiquitin-proteasome system cooperate to promote ERBB2-dependent esophageal cancer phenotype

(2012) O A Issaenko et al.   CANCER GENE THERAPY

Dynamic13C-labeling experiments prove important differences in protein turnover rate between twoSaccharomyces cerevisiaestrains

(2012) Kuk-Ki Hong et al.   FEMS YEAST RESEARCH

Yeast Endosulfines Control Entry into Quiescence and Chronological Life Span by Inhibiting Protein Phosphatase 2A

(2012) Séverine Bontron et al.   Cell Reports

The role of proteosome-mediated proteolysis in modulating potentially harmful transcription factor activity in Saccharomyces cerevisiae

(2011) Nicola Bonzanni et al.   BIOINFORMATICS

Promotion of Heat Shock Factor Hsf1 Degradation via Adaptor Protein Filamin A-interacting Protein 1-Like (FILIP-1L)

(2011) Yanzhong Hu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

JmjN interacts with JmjC to ensure selective proteolysis of Gis1 by the proteasome

(2011) Z. Quan et al.   MICROBIOLOGY-SGM

DEPTOR, an mTOR Inhibitor, Is a Physiological Substrate of SCFβTrCP E3 Ubiquitin Ligase and Regulates Survival and Autophagy

(2011) Yongchao Zhao et al.   MOLECULAR CELL

mTOR Generates an Auto-Amplification Loop by Triggering the βTrCP- and CK1α-Dependent Degradation of DEPTOR

(2011) Shanshan Duan et al.   MOLECULAR CELL

mTOR Drives Its Own Activation via SCFβTrCP-Dependent Degradation of the mTOR Inhibitor DEPTOR

(2011) Daming Gao et al.   MOLECULAR CELL

Initiation of the yeast G0program requires Igo1 and Igo2, which antagonize activation of decapping of specific nutrient-regulated mRNAs

(2011) Xuan Luo et al.   RNA Biology

Down-regulation of the ubiquitin–proteasome proteolysis system by amino acids and insulin involves the adenosine monophosphate-activated protein kinase and mammalian target of rapamycin pathways in rat hepatocytes

(2010) Nattida Chotechuang et al.   AMINO ACIDS

The proteasome and its regulatory roles in gene expression

(2010) Jaechan Kwak et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Proteolytic and non-proteolytic roles of ubiquitin and the ubiquitin proteasome system in transcriptional regulation

(2010) Kavita P. Bhat et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

mTORC1 signaling requires proteasomal function and the involvement of CUL4-DDB1 ubiquitin E3 ligase

(2010) Papia Ghosh et al.   CELL CYCLE

Gcn4p-mediated transcriptional repression of ribosomal protein genes under amino-acid starvation

(2010) Yoo Jin Joo et al.   EMBO JOURNAL

The mammalian target of rapamycin inhibitor RAD001 (everolimus) synergizes with chemotherapeutic agents, ionizing radiation and proteasome inhibitors in pre-B acute lymphocytic leukemia

(2010) P. Saunders et al.   HAEMATOLOGICA

Integration of General Amino Acid Control and Target of Rapamycin (TOR) Regulatory Pathways in Nitrogen Assimilation in Yeast

(2010) Kirk A. Staschke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Initiation of the TORC1-Regulated G0 Program Requires Igo1/2, which License Specific mRNAs to Evade Degradation via the 5′-3′ mRNA Decay Pathway

(2010) Nicolas Talarek et al.   MOLECULAR CELL

YEASTRACT: providing a programmatic access to curated transcriptional regulatory associations in Saccharomyces cerevisiae through a web services interface

(2010) D. Abdulrehman et al.   NUCLEIC ACIDS RESEARCH

Integrated multilaboratory systems biology reveals differences in protein metabolism between two reference yeast strains

(2010) André B. Canelas et al.   Nature Communications

Repression of protein translation and mTOR signaling by proteasome inhibitor in colon cancer cells

(2009) William Ka Kei Wu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival

(2009) Timothy R. Peterson et al.   CELL

Proteasomal Degradation of Rpn4 in Saccharomyces cerevisiae Is Critical for Cell Viability Under Stressed Conditions

(2009) X. Wang et al.   GENETICS

The Transcription Activity of Gis1 Is Negatively Modulated by Proteasome-mediated Limited Proteolysis

(2009) Nianshu Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The 19 S Proteasome Subcomplex Establishes a Specific Protein Interaction Network at the Promoter for Stimulated Transcriptional Initiationin Vivo

(2009) Shivani Malik et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1

(2009) Carson C. Thoreen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteasome Subunits Relocalize during Human Cytomegalovirus Infection, and Proteasome Activity Is Necessary for Efficient Viral Gene Transcription

(2009) K. Tran et al.   JOURNAL OF VIROLOGY

Gis1 is required for transcriptional reprogramming of carbon metabolism and the stress response during transition into stationary phase in yeast

(2009) N. Zhang et al.   MICROBIOLOGY-SGM

Active-Site Inhibitors of mTOR Target Rapamycin-Resistant Outputs of mTORC1 and mTORC2

(2009) Morris E Feldman et al.   PLOS BIOLOGY

Ubiquitin-independent degradation of proteins by the proteasome

(2008) Isabelle Jariel-Encontre et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Disruption of Rpn4-Induced Proteasome Expression in Saccharomyces cerevisiae Reduces Cell Viability Under Stressed Conditions

(2008) X. Wang et al.   GENETICS

Yeast Yak1 kinase, a bridge between PKA and stress-responsive transcription factors, Hsf1 and Msn2/Msn4

(2008) Peter Lee et al.   MOLECULAR MICROBIOLOGY

Caffeine extends yeast lifespan by targeting TORC1

(2008) Valeria Wanke et al.   MOLECULAR MICROBIOLOGY

A comprehensive strategy enabling high-resolution functional analysis of the yeast genome

(2008) David K Breslow et al.   NATURE METHODS

Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation

(2008) A. Y. Choo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA