Crosstalk between the Unfolded Protein Response and NF-κB-Mediated Inflammation in the Progression of Chronic Kidney Disease

4-Phenylbutyrate Inhibits Tunicamycin-Induced Acute Kidney Injury via CHOP/GADD153 Repression

(2014) Rachel E. Carlisle et al.   PLoS One

Prevalence estimates of chronic kidney disease in Canada: results of a nationally representative survey

(2013) P. Arora et al.   CANADIAN MEDICAL ASSOCIATION JOURNAL

Oral Treatment Targeting the Unfolded Protein Response Prevents Neurodegeneration and Clinical Disease in Prion-Infected Mice

(2013) J. A. Moreno et al.   Science Translational Medicine

IRE1: ER stress sensor and cell fate executor

(2013) Yani Chen et al.   TRENDS IN CELL BIOLOGY

Aberrant Recruitment and Activation of T Cells in Diabetic Nephropathy

(2012) Ju-Young Moon et al.   AMERICAN JOURNAL OF NEPHROLOGY

The unfolded protein response at the crossroads of cellular life and death during endoplasmic reticulum stress

(2012) Richard Jäger et al.   BIOLOGY OF THE CELL

The interplay between endoplasmic reticulum stress and inflammation

(2012) Sumaira Z Hasnain et al.   IMMUNOLOGY AND CELL BIOLOGY

Integrated Stress Response Modulates Cellular Redox State via Induction of Cystathionine γ-Lyase

(2012) Jeffrey G. Dickhout et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The impact of the unfolded protein response on human disease

(2012) Shiyu Wang et al.   JOURNAL OF CELL BIOLOGY

Discovery of 7-Methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a Potent and Selective First-in-Class Inhibitor of Protein Kinase R (PKR)-like Endoplasmic Reticulum Kinase (PERK)

(2012) Jeffrey M. Axten et al.   JOURNAL OF MEDICINAL CHEMISTRY

ER stress-induced inflammation: does it aid or impede disease progression?

(2012) Abhishek D. Garg et al.   TRENDS IN MOLECULAR MEDICINE

Structure–function analysis of the tertiary bile acid TUDCA for the resolution of endoplasmic reticulum stress in intestinal epithelial cells

(2011) Emanuel Berger et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cleavage of the CD11b extracellular domain by the leukocyte serprocidins is critical for neutrophil detachment during chemotaxis

(2011) K. Zen et al.   BLOOD

Cardiorenal syndrome in heart failure: A cardiologist's perspective

(2011) Peter P. Liu   CANADIAN JOURNAL OF CARDIOLOGY

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(2011) Chih-Kang Chiang et al.   MOLECULAR MEDICINE

Crosstalk in NF-κB signaling pathways

(2011) Andrea Oeckinghaus et al.   NATURE IMMUNOLOGY

The Unfolded Protein Response: Integrating Stress Signals Through the Stress Sensor IRE1α

(2011) Claudio Hetz et al.   PHYSIOLOGICAL REVIEWS

T lymphocytes mediate hypertension and kidney damage in Dahl salt-sensitive rats

(2010) Carmen De Miguel et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma

(2010) I. Papandreou et al.   BLOOD

Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease

(2010) Gökhan S. Hotamisligil   CELL

Endoplasmic reticulum stress as a progression factor for kidney injury

(2010) Reiko Inagi   CURRENT OPINION IN PHARMACOLOGY

Chronic kidney disease: a public health priority and harbinger of premature cardiovascular disease

(2010) P. Stenvinkel   JOURNAL OF INTERNAL MEDICINE

NF- B in Renal Inflammation

(2010) A. B. Sanz et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Albumin Overload Induces Apoptosis in Renal Tubular Epithelial Cells through a CHOP-Dependent Pathway

(2010) Xiaowei Wu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Effects of 4-phenylbutyric acid on the process and development of diabetic nephropathy induced in rats by streptozotocin: Regulation of endoplasmic reticulum stress-oxidative activation

(2010) Zhi-Feng Luo et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Endoplasmic Reticulum Stress and Renal Disease

(2009) Jeffrey G. Dickhout et al.   ANTIOXIDANTS & REDOX SIGNALING

Serum Indoxyl Sulfate Is Associated with Vascular Disease and Mortality in Chronic Kidney Disease Patients

(2009) F. C. Barreto et al.   Clinical Journal of the American Society of Nephrology

Activation of the Akt-NF- B Pathway by Subtilase Cytotoxin through the ATF6 Branch of the Unfolded Protein Response

(2009) H. Yamazaki et al.   JOURNAL OF IMMUNOLOGY

Monocyte Chemoattractant Protein-1 (MCP-1): An Overview

(2009) Satish L. Deshmane et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

The chemical chaperone 4-phenylbutyrate inhibits adipogenesis by modulating the unfolded protein response

(2009) Sana Basseri et al.   JOURNAL OF LIPID RESEARCH

Endoplasmic reticulum stress in proteinuric kidney disease

(2009) Andrey V. Cybulsky   KIDNEY INTERNATIONAL

Endoplasmic Reticulum Stress in the Kidney as a Novel Mediator of Kidney Injury

(2009) Reiko Inagi   NEPHRON EXPERIMENTAL NEPHROLOGY

Cyclosporine-Induced Endoplasmic Reticulum Stress Triggers Tubular Phenotypic Changes and Death

(2008) N. Pallet et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Dysfunction of the ER chaperone BiP accelerates the renal tubular injury

(2008) Keita Kimura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Role of Inflammation in the Development of Renal Damage and Dysfunction in Angiotensin II–Induced Hypertension

(2008) Tang-Dong Liao et al.   HYPERTENSION

Up regulation of the GRP-78 and GADD-153 and down regulation of Bcl-2 proteins in primary glomerular diseases: a possible involvement of the ER stress pathway in glomerulonephritis

(2008) Suchita Markan et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

From endoplasmic-reticulum stress to the inflammatory response

(2008) Kezhong Zhang et al.   NATURE

TNF-α inhibition reduces renal injury in DOCA-salt hypertensive rats

(2007) Ahmed A. Elmarakby et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY