Engineering dynamic cell cycle control with synthetic small molecule-responsive RNA devices

Engineering Complex Synthetic Transcriptional Programs with CRISPR RNA Scaffolds

(2015) Jesse G. Zalatan et al.   CELL

High-throughput cellular RNA device engineering

(2015) Brent Townshend et al.   NATURE METHODS

Control of alphavirus-based gene expression using engineered riboswitches

(2015) Christie L. Bell et al.   VIROLOGY

Synthetic feedback control using an RNAi-based gene-regulatory device

(2015) Ryan J Bloom et al.   Journal of Biological Engineering

Long-Term Episomal Transgene Expression from Mitotically Stable Integration-Deficient Lentiviral Vectors

(2014) Hanna Kymäläinen et al.   HUMAN GENE THERAPY

A general design strategy for protein-responsive riboswitches in mammalian cells

(2014) Simon Ausländer et al.   NATURE METHODS

Protein-responsive ribozyme switches in eukaryotic cells

(2014) Andrew B. Kennedy et al.   NUCLEIC ACIDS RESEARCH

Artificial riboswitches for gene expression and replication control of DNA and RNA viruses

(2014) Patrick Ketzer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-Based Single-Gene Circuits Buffer Protein Synthesis Rates against Perturbations

(2014) Timothy J. Strovas et al.   ACS Synthetic Biology

Merging high-quality biochemical fractionation with a refined flow cytometry approach to monitor nucleocytoplasmic protein expression throughout the unperturbed mammalian cell cycle

(2013) Margit Rosner et al.   Nature Protocols

Dynamically Reshaping Signaling Networks to Program Cell Fate via Genetic Controllers

(2013) K. E. Galloway et al.   SCIENCE

Amplifying Genetic Logic Gates

(2013) J. Bonnet et al.   SCIENCE

Synthetic Biology: Advancing the Design of Diverse Genetic Systems

(2013) Yen-Hsiang Wang et al.   Annual Review of Chemical and Biomolecular Engineering

A yeast-based rapid prototype platform for gene control elements in mammalian cells

(2012) Kathy Y. Wei et al.   BIOTECHNOLOGY AND BIOENGINEERING

High-throughput enzyme evolution in Saccharomyces cerevisiae using a synthetic RNA switch

(2012) Joshua K. Michener et al.   METABOLIC ENGINEERING

A high-throughput, quantitative cell-based screen for efficient tailoring of RNA device activity

(2012) Joe C. Liang et al.   NUCLEIC ACIDS RESEARCH

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Synthetic Reversal of Epigenetic Silencing

(2011) Karmella A. Haynes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Model-Driven Engineering of RNA Devices to Quantitatively Program Gene Expression

(2011) J. M. Carothers et al.   SCIENCE

A Synthetic Optogenetic Transcription Device Enhances Blood-Glucose Homeostasis in Mice

(2011) H. Ye et al.   SCIENCE

Multi-Input RNAi-Based Logic Circuit for Identification of Specific Cancer Cells

(2011) Z. Xie et al.   SCIENCE

Progressive Activation of CyclinB1-Cdk1 Coordinates Entry to Mitosis

(2010) Olivier Gavet et al.   DEVELOPMENTAL CELL

Genetic control of mammalian T-cell proliferation with synthetic RNA regulatory systems

(2010) Y. Y. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reprogramming Cellular Behavior with RNA Controllers Responsive to Endogenous Proteins

(2010) S. J. Culler et al.   SCIENCE

A Synthetic Genetic Edge Detection Program

(2009) Jeffrey J. Tabor et al.   CELL

Independent and high-level dual-gene expression in adult stem-progenitor cells from a single lentiviral vector

(2009) J Tian et al.   GENE THERAPY

Keeping an eye on retinoblastoma control of human embryonic stem cells

(2009) Jamie F. Conklin et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

A tunable synthetic mammalian oscillator

(2009) Marcel Tigges et al.   NATURE

Automated design of synthetic ribosome binding sites to control protein expression

(2009) Howard M Salis et al.   NATURE BIOTECHNOLOGY

Synthetic Gene Networks That Count

(2009) A. E. Friedland et al.   SCIENCE

Using Engineered Scaffold Interactions to Reshape MAP Kinase Pathway Signaling Dynamics

(2008) C. J. Bashor et al.   SCIENCE