Synthetic feedback control using an RNAi-based gene-regulatory device

Kinetic and Equilibrium Binding Characterization of Aptamers to Small Molecules using a Label-Free, Sensitive, and Scalable Platform

(2014) Andrew L. Chang et al.   ANALYTICAL CHEMISTRY

A quantitative framework for the forward design of synthetic miRNA circuits

(2014) Ryan J Bloom et al.   NATURE METHODS

Synthetic biology in mammalian cells: next generation research tools and therapeutics

(2014) Florian Lienert et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Protein-responsive ribozyme switches in eukaryotic cells

(2014) Andrew B. Kennedy et al.   NUCLEIC ACIDS RESEARCH

Physical Constraints on Biological Integral Control Design for Homeostasis and Sensory Adaptation

(2013) Jordan Ang et al.   BIOPHYSICAL JOURNAL

Synthetic mammalian transgene negative autoregulation

(2013) V. Shimoga et al.   Molecular Systems Biology

A yeast-based rapid prototype platform for gene control elements in mammalian cells

(2012) Kathy Y. Wei et al.   BIOTECHNOLOGY AND BIOENGINEERING

Foundations for the design and implementation of synthetic genetic circuits

(2012) Adrian L. Slusarczyk et al.   NATURE REVIEWS GENETICS

A versatile cis-blocking and trans-activation strategy for ribozyme characterization

(2012) Andrew B. Kennedy et al.   NUCLEIC ACIDS RESEARCH

A high-throughput, quantitative cell-based screen for efficient tailoring of RNA device activity

(2012) Joe C. Liang et al.   NUCLEIC ACIDS RESEARCH

MicroRNAs can generate thresholds in target gene expression

(2011) Shankar Mukherji et al.   NATURE GENETICS

Feedback Control of Protein Expression in Mammalian Cells by Tunable Synthetic Translational Inhibition

(2011) James A. Stapleton et al.   ACS Synthetic Biology

Rationally designed logic integration of regulatory signals in mammalian cells

(2010) Madeleine Leisner et al.   Nature Nanotechnology

Design of small molecule-responsive microRNAs based on structural requirements for Drosha processing

(2010) Chase L. Beisel et al.   NUCLEIC ACIDS RESEARCH

Reprogramming Cellular Behavior with RNA Controllers Responsive to Endogenous Proteins

(2010) S. J. Culler et al.   SCIENCE

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Frameworks for Programming Biological Function through RNA Parts and Devices

(2009) Maung Nyan Win et al.   CHEMISTRY & BIOLOGY

Conditional RNA Interference Mediated by Allosteric Ribozyme

(2009) Deepak Kumar et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Coupled RNA Processing and Transcription of Intergenic Primary MicroRNAs

(2009) M. Ballarino et al.   MOLECULAR AND CELLULAR BIOLOGY

A tunable synthetic mammalian oscillator

(2009) Marcel Tigges et al.   NATURE

The second wave of synthetic biology: from modules to systems

(2009) Priscilla E. M. Purnick et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Stem Cells, the Molecular Circuitry of Pluripotency and Nuclear Reprogramming

(2008) Rudolf Jaenisch et al.   CELL

Model-guided design of ligand-regulated RNAi for programmable control of gene expression

(2008) Chase L Beisel et al.   Molecular Systems Biology

MicroRNA-directed transcriptional gene silencing in mammalian cells

(2008) D. H. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA