Drug allergy

Drug reaction with Eosinophilia and Systemic Symptoms (DRESS) / Drug-induced Hypersensitivity Syndrome (DIHS): a review of current concepts

(2012) Paulo Ricardo Criado et al.   ANAIS BRASILEIROS DE DERMATOLOGIA

Hypersensitivity to antineoplastic agents: mechanisms and treatment with rapid desensitization

(2012) Mariana Castells et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Mechanisms involved in the Abacavir-mediated hypersensitivity syndrome

(2012) Anuska Llano et al.   CELL RESEARCH

Subthreshold desensitization of human basophils re-capitulates the loss of Syk and FcεRI expression characterized by other methods of desensitization

(2012) D. MacGlashan   CLINICAL AND EXPERIMENTAL ALLERGY

Hypersensitivity reactions in the anesthesia setting/allergic reactions to anesthetics

(2012) Paul M. Mertes et al.   Current Opinion in Allergy and Clinical Immunology

Role of immune reactions in drug-induced liver injury (DILI)

(2012) Cynthia Ju et al.   DRUG METABOLISM REVIEWS

Avidity determines T-cell reactivity in abacavir hypersensitivity

(2012) Jacqueline Adam et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Immune hemolytic anemia caused by drugs

(2012) George Garratty   Expert Opinion On Drug Safety

Recent advances in the genetics and immunology of Stevens-Johnson syndrome and toxic epidermal necrosis

(2012) Wen-Hung Chung et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Genetic and immune predictors for hypersensitivity syndrome to antiepileptic drugs

(2012) Manuela G. Neuman et al.   Translational Research

In silico analysis of HLA associations with drug-induced liver injury: use of a HLA-genotyped DNA archive from healthy volunteers

(2012) Ana Alfirevic et al.   Genome Medicine

Multiple drug hypersensitivity: normal Treg cell function but enhanced in vivo activation of drug-specific T cells

(2011) B. Daubner et al.   ALLERGY

Icatibant: a novel approach to the treatment of angioedema related to the use of angiotensin-converting enzyme inhibitors

(2011) Mauro Gallitelli et al.   AMERICAN JOURNAL OF EMERGENCY MEDICINE

Drug Hypersensitivity and Human Leukocyte Antigens of the Major Histocompatibility Complex

(2011) Mandvi Bharadwaj et al.   Annual Review of Pharmacology and Toxicology

Desensitization regimens for drug allergy: state of the art in the 21st century

(2011) A. Liu et al.   CLINICAL AND EXPERIMENTAL ALLERGY

ACE Inhibitor–Induced Angioedema

(2011) Monali Vasekar et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Immediate adverse reactions to biologicals: from pathogenic mechanisms to prophylactic management

(2011) Alessandra Vultaggio et al.   Current Opinion in Allergy and Clinical Immunology

Role of aspirin desensitization in the management of chronic rhinosinusitis

(2011) Habib Rizk   Current Opinion in Otolaryngology & Head and Neck Surgery

Genetic association studies in drug-induced liver injury

(2011) Ann K. Daly et al.   DRUG METABOLISM REVIEWS

Oral drug challenges in non-steroidal anti-inflammatory drug-induced urticaria, angioedema and anaphylaxis

(2011) T. Chaudhry et al.   INTERNAL MEDICINE JOURNAL

Enhanced antigenicity leads to altered immunogenicity in sulfamethoxazole-hypersensitive patients with cystic fibrosis

(2011) Ayman Elsheikh et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Immune pathomechanism of drug hypersensitivity reactions

(2011) Werner J. Pichler et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Shared and restricted T-cell receptor use is crucial for carbamazepine-induced Stevens-Johnson syndrome

(2011) Tai-Ming Ko et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The predominant drug-specific T-cell population may switch from cytotoxic T cells to regulatory T cells during the course of anticonvulsant-induced hypersensitivity

(2011) Takaaki Hanafusa et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Direct Evidence for the Formation of Diastereoisomeric Benzylpenicilloyl Haptens from Benzylpenicillin and Benzylpenicillenic Acid in Patients

(2011) X. Meng et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Mechanisms of drug-induced liver injury: from bedside to bench

(2011) Shannan Tujios et al.   Nature Reviews Gastroenterology & Hepatology

HLA-A*3101 and Carbamazepine-Induced Hypersensitivity Reactions in Europeans

(2011) Mark McCormack et al.   NEW ENGLAND JOURNAL OF MEDICINE

Human N-acetyltransferase 1 *10 and *11 alleles increase protein expression through distinct mechanisms and associate with sulfamethoxazole-induced hypersensitivity

(2011) Danxin Wang et al.   Pharmacogenetics and Genomics

Polymorphisms of Aspirin-Metabolizing EnzymesCYP2C9,NAT2andUGT1A6in Aspirin-Intolerant Urticaria

(2011) Nami Shrestha Palikhe et al.   Allergy Asthma & Immunology Research

General considerations on rapid desensitization for drug hypersensitivity - a consensus statement

(2010) J. R. Cernadas et al.   ALLERGY

Delayed drug hypersensitivity: models of T-cell stimulation

(2010) Jacqueline Adam et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Basophils are potent antigen-presenting cells that selectively induce Th2 cells

(2010) Kenji Nakanishi   EUROPEAN JOURNAL OF IMMUNOLOGY

Clinical practice

(2010) Hans de Groot et al.   EUROPEAN JOURNAL OF PEDIATRICS

Cross-Reactivity in Drug Hypersensitivity Reactions to Sulfasalazine and Sulfamethoxazole

(2010) Anna Zawodniak et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Molecular and structural determinants of adamantyl susceptibility to HLA-DRs allelic variants: an in silico approach to understand the mechanism of MLEs

(2010) Zaheer-ul-Haq et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Drug Antigenicity, Immunogenicity, and Costimulatory Signaling: Evidence for Formation of a Functional Antigen through Immune Cell Metabolism

(2010) A. Elsheikh et al.   JOURNAL OF IMMUNOLOGY

The Complex Clinical Picture of β-Lactam Hypersensitivity: Penicillins, Cephalosporins, Monobactams, Carbapenems, and Clavams

(2010) Maria J. Torres et al.   MEDICAL CLINICS OF NORTH AMERICA

Drug-induced liver injury: past, present and future

(2010) Ann K Daly   PHARMACOGENOMICS

Aspirin sensitivity and desensitization for asthma and sinusitis

(2009) Donald D. Stevenson   CURRENT ALLERGY AND ASTHMA REPORTS

The Variable Clinical Picture of Drug-Induced Hypersensitivity Syndrome/Drug Rash with Eosinophilia and Systemic Symptoms in Relation to the Eliciting Drug

(2009) Yoko Kano et al.   IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA

Determinants of allergenicity

(2009) Claudia Traidl-Hoffmann et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Defective Regulatory T Cells In Patients with Severe Drug Eruptions: Timing of the Dysfunction Is Associated with the Pathological Phenotype and Outcome

(2009) R. Takahashi et al.   JOURNAL OF IMMUNOLOGY

"Danger" Conditions Increase Sulfamethoxazole-Protein Adduct Formation in Human Antigen-Presenting Cells

(2009) S. N. Lavergne et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

AllerHunter: A SVM-Pairwise System for Assessment of Allergenicity and Allergic Cross-Reactivity in Proteins

(2009) Hon Cheng Muh et al.   PLoS One

Characterisation of flucloxacillin and 5-hydroxymethyl flucloxacillin haptenated HSAin vitroandin vivo

(2009) Rosalind E. Jenkins et al.   Proteomics Clinical Applications

In vivo dynamics of intraepidermal CD8+ T cells and CD4+ T cells during the evolution of fixed drug eruption

(2008) Y. Mizukawa et al.   BRITISH JOURNAL OF DERMATOLOGY

Fixed drug eruption: A prototypic disorder mediated by effector memory T cells

(2008) Yoshiko Mizukawa et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Human Leukocyte Antigen Class I-Restricted Activation of CD8+ T Cells Provides the Immunogenetic Basis of a Systemic Drug Hypersensitivity

(2008) Diana Chessman et al.   IMMUNITY