The generation of induced pluripotent stem cells for macular degeneration as a drug screening platform: identification of curcumin as a protective agent for retinal pigment epithelial cells against oxidative stress

Oxidative Stress, Hypoxia, and Autophagy in the Neovascular Processes of Age-Related Macular Degeneration

(2014) Janusz Blasiak et al.   Biomed Research International

Role of antioxidant enzymes and small molecular weight antioxidants in the pathogenesis of age-related macular degeneration (AMD)

(2013) Paulina Tokarz et al.   BIOGERONTOLOGY

Genetic factors and AMD

(2013) Ian MacDonald et al.   CANADIAN JOURNAL OF OPHTHALMOLOGY-JOURNAL CANADIEN D OPHTALMOLOGIE

A Review of Therapeutic Effects of Curcumin

(2013) Ali Noorafshan et al.   CURRENT PHARMACEUTICAL DESIGN

A Commentary on iPS Cells: Potential Applications in Autologous Transplantation, Study of Illnesses and Drug Screening

(2013) Gaetano Romano et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Curcumin Ameliorates the Neurodegenerative Pathology in A53T α-synuclein Cell Model of Parkinson’s Disease Through the Downregulation of mTOR/p70S6K Signaling and the Recovery of Macroautophagy

(2013) Tian-Fang Jiang et al.   Journal of Neuroimmune Pharmacology

Cytotoxic Effects of Curcumin in Human Retinal Pigment Epithelial Cells

(2013) Margrit Hollborn et al.   PLoS One

Efficient Generation of Integration-Free iPS Cells from Human Adult Peripheral Blood Using BCL-XL Together with Yamanaka Factors

(2013) Rui-Jun Su et al.   PLoS One

Retinal iron homeostasis in health and disease

(2013) Delu Song et al.   Frontiers in Aging Neuroscience

Co-morbidity of depression and anxiety in common age-related eye diseases: a population-based study of 662 adults

(2013) Ranmalee Eramudugolla et al.   Frontiers in Aging Neuroscience

Corneal repair by human corneal keratocyte-reprogrammed iPSCs and amphiphatic carboxymethyl-hexanoyl chitosan hydrogel

(2012) Yueh Chien et al.   BIOMATERIALS

iPS cell modeling of Best disease: insights into the pathophysiology of an inherited macular degeneration

(2012) Ruchira Singh et al.   HUMAN MOLECULAR GENETICS

Embryonic stem cell trials for macular degeneration: a preliminary report

(2012) Steven D Schwartz et al.   LANCET

How does the macula protect itself from oxidative stress?

(2012) James T. Handa   MOLECULAR ASPECTS OF MEDICINE

Generation of induced pluripotent stem cells from a small amount of human peripheral blood using a combination of activated T cells and Sendai virus

(2012) Tomohisa Seki et al.   Nature Protocols

Age-related macular degeneration: the importance of family history as a risk factor

(2011) Humma Shahid et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

INNER SEGMENT–OUTER SEGMENT JUNCTIONAL LAYER INTEGRITY AND CORRESPONDING RETINAL SENSITIVITY IN DRY AND WET FORMS OF AGE-RELATED MACULAR DEGENERATION

(2011) Gennady Landa et al.   RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES

Curcumin as a therapeutic agent: the evidence from in vitro, animal and human studies

(2010) Jenny Epstein et al.   BRITISH JOURNAL OF NUTRITION

Reprogramming of Human Peripheral Blood Cells to Induced Pluripotent Stem Cells

(2010) Judith Staerk et al.   Cell Stem Cell

An imbalance of human complement regulatory proteins CFHR1, CFHR3 and factor H influences risk for age-related macular degeneration (AMD)

(2010) Lars G. Fritsche et al.   HUMAN MOLECULAR GENETICS

Generation of induced pluripotent stem cells from human blood

(2009) Y.-H. Loh et al.   BLOOD

Generation of Induced Pluripotent Stem Cells from Human Cord Blood

(2009) Alexandra Haase et al.   Cell Stem Cell

Technical Challenges in Using Human Induced Pluripotent Stem Cells to Model Disease

(2009) Krishanu Saha et al.   Cell Stem Cell

Induced pluripotent stem cells generated without viral integration

(2009) Reto Eggenschwiler et al.   HEPATOLOGY

In vitro differentiation of retinal cells from human pluripotent stem cells by small-molecule induction

(2009) F. Osakada et al.   JOURNAL OF CELL SCIENCE

Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome

(2009) Noemi FUSAKI et al.   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Generation of pluripotent stem cells from patients with type 1 diabetes

(2009) R. Maehr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Disease-Specific Induced Pluripotent Stem Cells

(2008) In-Hyun Park et al.   CELL

Curcumin protects retinal cells from light-and oxidant stress-induced cell death

(2008) Md Nawajes A. Mandal et al.   FREE RADICAL BIOLOGY AND MEDICINE

Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases

(2008) Bharat B. Aggarwal et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Age-Related Macular Degeneration

(2008) Rama D. Jager et al.   NEW ENGLAND JOURNAL OF MEDICINE

Induced Pluripotent Stem Cells Generated Without Viral Integration

(2008) M. Stadtfeld et al.   SCIENCE

Induced Pluripotent Stem Cells Generated from Patients with ALS Can Be Differentiated into Motor Neurons

(2008) J. T. Dimos et al.   SCIENCE