Curcumin Ameliorates the Neurodegenerative Pathology in A53T α-synuclein Cell Model of Parkinson’s Disease Through the Downregulation of mTOR/p70S6K Signaling and the Recovery of Macroautophagy

PPARγ Agonist Curcumin Reduces the Amyloid-β-Stimulated Inflammatory Responses in Primary Astrocytes

(2017) Hong-Mei Wang et al.   JOURNAL OF ALZHEIMERS DISEASE

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

(2014) Daniel J. Klionsky et al.   Autophagy

Knockdown Survivin Expression Reduces the Efficacy of Curcumin Treatment in Hepatocellular Carcinoma Cells

(2012) Chin-Sheng Hung et al.   ANNALS OF SURGICAL ONCOLOGY

Curcumin-induced autophagy contributes to the decreased survival of oral cancer cells

(2012) Ji Young Kim et al.   ARCHIVES OF ORAL BIOLOGY

Isorhynchophylline, a natural alkaloid, promotes the degradation of alpha-synuclein in neuronal cells via inducing autophagy

(2012) Jia-Hong Lu et al.   Autophagy

Plant natural compounds: targeting pathways of autophagy as anti-cancer therapeutic agents

(2012) X. Zhang et al.   CELL PROLIFERATION

Aggregate Clearance of α-Synuclein inSaccharomyces cerevisiaeDepends More on Autophagosome and Vacuole Function Than on the Proteasome

(2012) Doris Petroi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Curcumin Prevents Aggregation in α-Synuclein by Increasing Reconfiguration Rate

(2012) Basir Ahmad et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Curcumin has Neuroprotection Effect on Homocysteine Rat Model of Parkinson

(2012) Zahra Mansouri et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Involvement of Macroautophagy in Multiple System Atrophy and Protein Aggregate Formation in Oligodendrocytes

(2012) Lisa Schwarz et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Extracellular signal-regulated kinase is involved in alpha-synuclein-induced mitochondrial dynamic disorders by regulating dynamin-like protein 1

(2012) Ya-Xing Gui et al.   NEUROBIOLOGY OF AGING

Effect of Trehalose on PC12 Cells Overexpressing Wild-Type or A53T Mutant α-synuclein

(2012) Dan-Mei Lan et al.   NEUROCHEMICAL RESEARCH

Curcumin inhibition of JNKs prevents dopaminergic neuronal loss in a mouse model of Parkinson’s disease through suppressing mitochondria dysfunction

(2012) Jing Pan et al.   Translational Neurodegeneration

Curcumin promotes differentiation of glioma-initiating cells by inducing autophagy

(2011) Wenzhuo Zhuang et al.   CANCER SCIENCE

Autophagy: for better or for worse

(2011) Ellen Wirawan et al.   CELL RESEARCH

Autophagy is induced by 3β-O-succinyl-lupeol (LD9-4) in A549 cells via up-regulation of Beclin 1 and down-regulation mTOR pathway

(2011) Jing Hao et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Curcumin protects against A53T alpha-synuclein-induced toxicity in a PC12 inducible cell model for Parkinsonism

(2011) Zhaohui Liu et al.   PHARMACOLOGICAL RESEARCH

Curcumin reduces α-synuclein induced cytotoxicity in Parkinson's disease cell model

(2010) Min S Wang et al.   BMC NEUROSCIENCE

The role of the Atg1/ULK1 complex in autophagy regulation

(2010) Noboru Mizushima   CURRENT OPINION IN CELL BIOLOGY

α-Synuclein impairs macroautophagy: implications for Parkinson’s disease

(2010) Ashley R. Winslow et al.   JOURNAL OF CELL BIOLOGY

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

Selective Molecular Alterations in the Autophagy Pathway in Patients with Lewy Body Disease and in Models of α-Synucleinopathy

(2010) Leslie Crews et al.   PLoS One

Glial Innate Immunity Generated by Non-Aggregated Alpha-Synuclein in Mouse: Differences between Wild-type and Parkinson's Disease-Linked Mutants

(2010) Cintia Roodveldt et al.   PLoS One

Mammalian autophagy: core molecular machinery and signaling regulation

(2009) Zhifen Yang et al.   CURRENT OPINION IN CELL BIOLOGY

Dynamic Changes in Presynaptic and Axonal Transport Proteins Combined with Striatal Neuroinflammation Precede Dopaminergic Neuronal Loss in a Rat Model of AAV  -Synucleinopathy

(2009) C. Y. Chung et al.   JOURNAL OF NEUROSCIENCE

Beclin 1 Gene Transfer Activates Autophagy and Ameliorates the Neurodegenerative Pathology in  -Synuclein Models of Parkinson's and Lewy Body Diseases

(2009) B. Spencer et al.   JOURNAL OF NEUROSCIENCE

Curcumin Inhibits the Proteasome Activity in Human Colon Cancer Cells In vitro and In vivo

(2008) V. Milacic et al.   CANCER RESEARCH

α-Synuclein Aggregates Interfere with Parkin Solubility and Distribution

(2008) Kohichi Kawahara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE

Conformational Equilibria in Monomeric α-Synuclein at the Single-Molecule Level

(2008) Massimo Sandal et al.   PLOS BIOLOGY