Transmembrane signal transduction by peptide hormones via family B G protein-coupled receptors
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Transmembrane signal transduction by peptide hormones via family B G protein-coupled receptors
Authors
Keywords
-
Journal
Frontiers in Pharmacology
Volume 6, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2015-11-05
DOI
10.3389/fphar.2015.00264
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Triblock peptide–linker–lipid molecular design improves potency of peptide ligands targeting family B G protein-coupled receptors
- (2015) Yuting Liu et al. CHEMICAL COMMUNICATIONS
- Activation of Corticotropin-Releasing Factor 1 Receptor: Insights from Molecular Dynamics Simulations
- (2015) Rajesh Singh et al. JOURNAL OF PHYSICAL CHEMISTRY B
- GPCR structures in drug design, emerging opportunities with new structures
- (2014) Christofer S. Tautermann BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Structure of Class B GPCRs: new horizons for drug discovery
- (2014) Andrea Bortolato et al. BRITISH JOURNAL OF PHARMACOLOGY
- Toward Fluorescent Probes for G-Protein-Coupled Receptors (GPCRs)
- (2014) Zhao Ma et al. JOURNAL OF MEDICINAL CHEMISTRY
- A Potent α/β-Peptide Analogue of GLP-1 with Prolonged Action in Vivo
- (2014) Lisa M. Johnson et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Unifying Family A GPCR Theories of Activation
- (2014) Benjamin G. Tehan et al. PHARMACOLOGY & THERAPEUTICS
- Structural features of the G-protein/GPCR interactions
- (2013) Irina S. Moreira BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Identification of key residues involved in adrenomedullin binding to the AM1receptor
- (2013) HA Watkins et al. BRITISH JOURNAL OF PHARMACOLOGY
- Insights into congenital stationary night blindness based on the structure of G90D rhodopsin
- (2013) Ankita Singhal et al. EMBO REPORTS
- Structural and Pharmacological Characterization of Novel Potent and Selective Monoclonal Antibody Antagonists of Glucose-dependent Insulinotropic Polypeptide Receptor
- (2013) Peter Ravn et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inhibitory Mechanism of an Allosteric Antibody Targeting the Glucagon Receptor
- (2013) Susmith Mukund et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structure of class B GPCR corticotropin-releasing factor receptor 1
- (2013) Kaspar Hollenstein et al. NATURE
- Structure of the human glucagon class B G-protein-coupled receptor
- (2013) Fai Yiu Siu et al. NATURE
- A β-Peptide Agonist of the GLP-1 Receptor, a Class B GPCR
- (2013) Elizabeth V. Denton et al. ORGANIC LETTERS
- Polar transmembrane interactions drive formation of ligand-specific and signal pathway-biased family B G protein-coupled receptor conformations
- (2013) D. Wootten et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Insights into the structure of class B GPCRs
- (2013) Kaspar Hollenstein et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Interaction of Protease-Activated Receptor 2 with G Proteins and β-Arrestin 1 Studied by Bioluminescence Resonance Energy Transfer
- (2013) Mohammed Akli Ayoub et al. Frontiers in Endocrinology
- Calcium-Dependent Ligand Binding and G-protein Signaling of Family B GPCR Parathyroid Hormone 1 Receptor Purified in Nanodiscs
- (2012) Nivedita Mitra et al. ACS Chemical Biology
- Structure and mechanism for recognition of peptide hormones by Class B G-protein-coupled receptors
- (2012) Kuntal Pal et al. ACTA PHARMACOLOGICA SINICA
- Differential determinants for coupling of distinct G proteins with the class B secretin receptor
- (2012) Gene L. Garcia et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Spatial proximity between the VPAC1 receptor and the amino terminus of agonist and antagonist peptides reveals distinct sites of interaction
- (2012) Emilie Ceraudo et al. FASEB JOURNAL
- Mapping spatial approximations between the amino terminus of secretin and each of the extracellular loops of its receptor using cysteine trapping
- (2012) Maoqing Dong et al. FASEB JOURNAL
- Modulation of the Interaction between Neurotensin Receptor NTS1 and Gq Protein by Lipid
- (2012) Sayaka Inagaki et al. JOURNAL OF MOLECULAR BIOLOGY
- Similarity between class A and class B G-protein-coupled receptors exemplified through calcitonin gene-related peptide receptor modelling and mutagenesis studies
- (2012) S. Vohra et al. Journal of the Royal Society Interface
- The GPCR Network: a large-scale collaboration to determine human GPCR structure and function
- (2012) Raymond C. Stevens et al. NATURE REVIEWS DRUG DISCOVERY
- Predicted structure of agonist-bound glucagon-like peptide 1 receptor, a class B G protein-coupled receptor
- (2012) A. Kirkpatrick et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Molecular basis for negative regulation of the glucagon receptor
- (2012) C. M. Koth et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Glucagon-like peptide-1 receptor dimerization differentially regulates agonist signaling but does not affect small molecule allostery
- (2012) K. G. Harikumar et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Distinct roles of metabotropic glutamate receptor dimerization in agonist activation and G-protein coupling
- (2012) D. El Moustaine et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Insights into the impact of phenolic residue incorporation at each position along secretin for receptor binding and biological activity
- (2012) Maoqing Dong et al. REGULATORY PEPTIDES
- Receptor Oligomerization in Family B1 of G-Protein-Coupled Receptors: Focus on BRET Investigations and the Link between GPCR Oligomerization and Binding Cooperativity
- (2012) Sarah Norklit Roed et al. Frontiers in Endocrinology
- Importance of Each Residue within Secretin for Receptor Binding and Biological Activity
- (2011) Maoqing Dong et al. BIOCHEMISTRY
- Artificial membrane-like environments for in vitro studies of purified G-protein coupled receptors
- (2011) Eugene Serebryany et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Extracellular loops 1 and 3 and their associated transmembrane regions of the calcitonin receptor-like receptor are needed for CGRP receptor function
- (2011) James Barwell et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- The structure and function of the glucagon-like peptide-1 receptor and its ligands
- (2011) Dan Donnelly BRITISH JOURNAL OF PHARMACOLOGY
- The Family B1 GPCR: Structural Aspects and Interaction with Accessory Proteins
- (2011) Alain Couvineau et al. CURRENT DRUG TARGETS
- Second Extracellular Loop of Human Glucagon-like Peptide-1 Receptor (GLP-1R) Has a Critical Role in GLP-1 Peptide Binding and Receptor Activation
- (2011) Cassandra Koole et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Molecular Basis of Secretin Docking to Its Intact Receptor Using Multiple Photolabile Probes Distributed throughout the Pharmacophore
- (2011) Maoqing Dong et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Refinement of Glucagon-like Peptide 1 Docking to Its Intact Receptor Using Mid-region Photolabile Probes and Molecular Modeling
- (2011) Laurence J. Miller et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Residues within the Transmembrane Domain of the Glucagon-Like Peptide-1 Receptor Involved in Ligand Binding and Receptor Activation: Modelling the Ligand-Bound Receptor
- (2011) K. Coopman et al. MOLECULAR ENDOCRINOLOGY
- Structure of the human histamine H1 receptor complex with doxepin
- (2011) Tatsuro Shimamura et al. NATURE
- Crystal structure of metarhodopsin II
- (2011) Hui-Woog Choe et al. NATURE
- The structural basis of agonist-induced activation in constitutively active rhodopsin
- (2011) Jörg Standfuss et al. NATURE
- The structural basis for agonist and partial agonist action on a β1-adrenergic receptor
- (2011) Tony Warne et al. NATURE
- Crystal structure of the β2 adrenergic receptor–Gs protein complex
- (2011) Søren G. F. Rasmussen et al. NATURE
- Inactive-state preassembly of Gq-coupled receptors and Gq heterotrimers
- (2011) Kou Qin et al. Nature Chemical Biology
- Analysis of the glucagon receptor first extracellular loop by the substituted cysteine accessibility method
- (2011) David J. Roberts et al. PEPTIDES
- Regulation of G Protein-Coupled Receptor Function by Na+/H+ Exchange Regulatory Factors
- (2011) J. A. Ardura et al. PHARMACOLOGICAL REVIEWS
- Crystal Structure of the PAC1R Extracellular Domain Unifies a Consensus Fold for Hormone Recognition by Class B G-Protein Coupled Receptors
- (2011) Shiva Kumar et al. PLoS One
- Stabilized G protein binding site in the structure of constitutively active metarhodopsin-II
- (2011) X. Deupi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural basis for extracellular interactions between calcitonin receptor-like receptor and receptor activity-modifying protein 2 for adrenomedullin-specific binding
- (2011) Seisuke Kusano et al. PROTEIN SCIENCE
- Structural insights into RAMP modification of secretin family G protein-coupled receptors: implications for drug development
- (2011) Julia K. Archbold et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Structure and Activation of the Visual Pigment Rhodopsin
- (2010) Steven O. Smith Annual Review of Biophysics
- Complexes between photoactivated rhodopsin and transducin: progress and questions
- (2010) Beata Jastrzebska et al. BIOCHEMICAL JOURNAL
- Molecular basis of parathyroid hormone receptor signaling and trafficking: a family B GPCR paradigm
- (2010) Jean-Pierre Vilardaga et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Mutational and Cysteine Scanning Analysis of the Glucagon Receptor N-terminal Domain
- (2010) Martine Prévost et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dimeric Arrangement of the Parathyroid Hormone Receptor and a Structural Mechanism for Ligand-induced Dissociation
- (2010) Augen A. Pioszak et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structural Basis for Hormone Recognition by the Human CRFR2α G Protein-coupled Receptor
- (2010) Kuntal Pal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Na/H Exchanger Regulatory Factors Control Parathyroid Hormone Receptor Signaling by Facilitating Differential Activation of Gα Protein Subunits
- (2010) Bin Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Identification of Determinants of Glucose-Dependent Insulinotropic Polypeptide Receptor That Interact with N-Terminal Biologically Active Region of the Natural Ligand
- (2010) T. Yaqub et al. MOLECULAR PHARMACOLOGY
- Structures of the CXCR4 Chemokine GPCR with Small-Molecule and Cyclic Peptide Antagonists
- (2010) B. Wu et al. SCIENCE
- Structure of the Human Dopamine D3 Receptor in Complex with a D2/D3 Selective Antagonist
- (2010) E. Y. T. Chien et al. SCIENCE
- Crystal Structure of the Ectodomain Complex of the CGRP Receptor, a Class-B GPCR, Reveals the Site of Drug Antagonism
- (2010) Ernst ter Haar et al. STRUCTURE
- Structure-function relationships of the N-terminus of receptor activity-modifying proteins
- (2009) Tao Qi et al. BRITISH JOURNAL OF PHARMACOLOGY
- Molecular Basis of Glucagon-like Peptide 1 Docking to Its Intact Receptor Studied with Carboxyl-terminal Photolabile Probes
- (2009) Quan Chen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structural Basis for Parathyroid Hormone-related Protein Binding to the Parathyroid Hormone Receptor and Design of Conformation-selective Peptides
- (2009) Augen A. Pioszak et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Crystal Structure of Glucagon-like Peptide-1 in Complex with the Extracellular Domain of the Glucagon-like Peptide-1 Receptor
- (2009) Christina Rye Underwood et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Molecular and Conformational Determinants of Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) for Activation of the PAC1 Receptor
- (2009) Steve Bourgault et al. JOURNAL OF MEDICINAL CHEMISTRY
- Alanine Scanning Mutagenesis of the Second Extracellular Loop of Type 1 Corticotropin-Releasing Factor Receptor Revealed Residues Critical for Peptide Binding
- (2009) K. Gkountelias et al. MOLECULAR PHARMACOLOGY
- Functional Importance of a Structurally Distinct Homodimeric Complex of the Family B G Protein-Coupled Secretin Receptor
- (2009) F. Gao et al. MOLECULAR PHARMACOLOGY
- Sustained cyclic AMP production by parathyroid hormone receptor endocytosis
- (2009) Sébastien Ferrandon et al. Nature Chemical Biology
- Fine-tuning of GPCR activity by receptor-interacting proteins
- (2009) Stefanie L. Ritter et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Helix movement is coupled to displacement of the second extracellular loop in rhodopsin activation
- (2009) Shivani Ahuja et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Mapping interaction sites within the N-terminus of the calcitonin gene-related peptide receptor; the role of residues 23–60 of the calcitonin receptor-like receptor
- (2009) James Barwell et al. PEPTIDES
- The effect of ligand efficacy on the formation and stability of a GPCR-G protein complex
- (2009) X. J. Yao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Passing the baton in class B GPCRs: peptide hormone activation via helix induction?
- (2009) Christoph Parthier et al. TRENDS IN BIOCHEMICAL SCIENCES
- Residue 17 of Sauvagine Cross-links to the First Transmembrane Domain of Corticotropin-releasing Factor Receptor 1 (CRFR1)
- (2008) Iman Assil-Kishawi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Molecular Recognition of Corticotropin-releasing Factor by Its G-protein-coupled Receptor CRFR1
- (2008) Augen A. Pioszak et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Crystal Structure of the Ligand-bound Glucagon-like Peptide-1 Receptor Extracellular Domain
- (2008) Steffen Runge et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Rapid Incorporation of Functional Rhodopsin into Nanoscale Apolipoprotein Bound Bilayer (NABB) Particles
- (2008) Sourabh Banerjee et al. JOURNAL OF MOLECULAR BIOLOGY
- Conformational Changes in the Parathyroid Hormone Receptor Associated with Activation by Agonist
- (2008) Beena E. Thomas et al. MOLECULAR ENDOCRINOLOGY
- Spatial Approximation between Secretin Residue Five and the Third Extracellular Loop of Its Receptor Provides New Insight into the Molecular Basis of Natural Agonist Binding
- (2008) M. Dong et al. MOLECULAR PHARMACOLOGY
- Crystal structure of opsin in its G-protein-interacting conformation
- (2008) Patrick Scheerer et al. NATURE
- Structural diversity of G protein-coupled receptors and significance for drug discovery
- (2008) Malin C. Lagerström et al. NATURE REVIEWS DRUG DISCOVERY
- First Cytoplasmic Loop of Glucagon-like Peptide-1 Receptor Can Function at the Third Cytoplasmic Loop Position of Rhodopsin
- (2008) Takahiro Yamashita et al. PHOTOCHEMISTRY AND PHOTOBIOLOGY
- Two protonation switches control rhodopsin activation in membranes
- (2008) M. Mahalingam et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- High-resolution distance mapping in rhodopsin reveals the pattern of helix movement due to activation
- (2008) C. Altenbach et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Prolonged signaling at the parathyroid hormone receptor by peptide ligands targeted to a specific receptor conformation
- (2008) M. Okazaki et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Molecular recognition of parathyroid hormone by its G protein-coupled receptor
- (2008) Augen A. Pioszak et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The 2.6 Angstrom Crystal Structure of a Human A2A Adenosine Receptor Bound to an Antagonist
- (2008) V.-P. Jaakola et al. SCIENCE
- Class-B GPCR activation: is ligand helix-capping the key?
- (2008) Jean-Michel Neumann et al. TRENDS IN BIOCHEMICAL SCIENCES
- GPCR monomers and oligomers: it takes all kinds
- (2008) Vsevolod V. Gurevich et al. TRENDS IN NEUROSCIENCES
- The Vasoactive Intestinal Peptide (VIP) α-Helix Up to C Terminus Interacts with the N-Terminal Ectodomain of the Human VIP/Pituitary Adenylate Cyclase-Activating Peptide 1 Receptor: Photoaffinity, Molecular Modeling, and Dynamics
- (2007) Emilie Ceraudo et al. MOLECULAR ENDOCRINOLOGY
- Altered Selectivity of Parathyroid Hormone (PTH) and PTH-Related Protein (PTHrP) for Distinct Conformations of the PTH/PTHrP Receptor
- (2007) Thomas Dean et al. MOLECULAR ENDOCRINOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now