Detection of ubiquitinated huntingtin species in intracellular aggregates
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Title
Detection of ubiquitinated huntingtin species in intracellular aggregates
Authors
Keywords
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Journal
Frontiers in Molecular Neuroscience
Volume 8, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2015-01-28
DOI
10.3389/fnmol.2015.00001
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Related references
Note: Only part of the references are listed.- Differential ubiquitination and degradation of huntingtin fragments modulated by ubiquitin-protein ligase E3A
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- Expanded Polyglutamine-containing N-terminal Huntingtin Fragments Are Entirely Degraded by Mammalian Proteasomes
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- Identification of NUB1 as a suppressor of mutant Huntingtin toxicity via enhanced protein clearance
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- The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes
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- Protein aggregates in Huntington's disease
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- Tumor Necrosis Factor Receptor-associated Factor 6 (TRAF6) Associates with Huntingtin Protein and Promotes Its Atypical Ubiquitination to Enhance Aggregate Formation
- (2011) Silvia Zucchelli et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Identifying polyglutamine protein species in situ that best predict neurodegeneration
- (2011) Jason Miller et al. Nature Chemical Biology
- Inhibiting the ubiquitin–proteasome system leads to preferential accumulation of toxic N-terminal mutant huntingtin fragments
- (2010) Xiang Li et al. HUMAN MOLECULAR GENETICS
- Huntington's disease: from molecular pathogenesis to clinical treatment
- (2010) Christopher A Ross et al. LANCET NEUROLOGY
- Modulation of Mutant Huntingtin N-Terminal Cleavage and Its Effect on Aggregation and Cell Death
- (2010) Katrin Juenemann et al. NEUROTOXICITY RESEARCH
- Polyglutamine Diseases: Where does Toxicity Come from? What is Toxicity? Where are We Going?
- (2010) T. Takahashi et al. Journal of Molecular Cell Biology
- Intranuclear Degradation of Polyglutamine Aggregates by the Ubiquitin-Proteasome System
- (2009) Atsushi Iwata et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome
- (2009) Leslie Michels Thompson et al. JOURNAL OF CELL BIOLOGY
- Adapting Proteostasis for Disease Intervention
- (2008) William E. Balch et al. SCIENCE
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