Review
Obstetrics & Gynecology
Maryam Kazemi, Joy Y. Kim, Cynthia Wan, Julia D. Xiong, Julia Michalak, Isabella B. Xavier, Kiran Ganga, Chau Thien Tay, Jessica A. Grieger, Stephen A. Parry, Lisa J. Moran, Marla E. Lujan
Summary: This study aimed to explore and compare the dietary and physical activity behaviors between women with polycystic ovary syndrome (PCOS) and those without PCOS. The findings indicated that women with PCOS had lower overall diet quality, poorer dietary intake (higher cholesterol and lower magnesium and zinc), and lower levels of physical activity compared to women without PCOS. These results highlight the need for targeted interventions to address these lifestyle behaviors in order to manage the complications associated with PCOS.
HUMAN REPRODUCTION UPDATE
(2022)
Article
Medicine, General & Internal
Malgorzata Mizgier, Grazyna Jarzabek-Bielecka, Dorota Formanowicz, Elzbieta Jodlowska-Siewert, Kinga Mruczyk, Angelika Cisek-Wozniak, Witold Kedzia, Justyna Opydo-Szymaczek
Summary: The study found that girls with PCOS had higher fat intake and lower levels of physical activity compared to the control group. Additionally, PCOS patients showed abnormal levels of metabolic and inflammatory markers.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Obstetrics & Gynecology
Fuensanta Navarro-Lafuente, Julian J. Arense-Gonzalo, Maria L. Sanchez-Ferrer, Maria T. Prieto-Sanchez, Ana Cutillas-Tolin, Jaime Mendiola, Evdochia Adoamnei, Esteban Gazabat-Barbado, Jesus Vioque, Alberto M. Torres-Cantero
Summary: This study suggests that higher intakes of specific fatty acids are related to some PCOS phenotypes.
REPRODUCTIVE BIOMEDICINE ONLINE
(2022)
Article
Endocrinology & Metabolism
Alexandra E. Butler, Abu Saleh Md Moin, Zeljko Reiner, Thozhukat Sathyapalan, Tannaz Jamialahmadi, Amirhossein Sahebkar, Stephen L. Atkin
Summary: Proteomic analysis was conducted to investigate the mechanism of dyslipidemia in women with polycystic ovary syndrome (PCOS), and whether it is related to obesity and insulin resistance (IR) or intrinsic to PCOS. The analysis revealed altered levels of certain proteins associated with lipid metabolism in PCOS women, suggesting increased cardiovascular risk even in the absence of obesity and IR.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Nutrition & Dietetics
Malgorzata Mizgier, Rafal Watrowski, Justyna Opydo-Szymaczek, Elzbieta Jodlowska-Siewert, Giovanni Lombardi, Witold Kedzia, Grazyna Jarzabek-Bielecka
Summary: The study found positive correlations between dietary fats and hormone parameters in PCOS and healthy girls, as well as positive correlation between SHBG and protein intake and negative correlation between SHBG and carbohydrate intake. In PCOS patients, an inverse correlation was observed between androgen concentrations and work/school and/or leisure time physical activity.
Article
Endocrinology & Metabolism
Anju E. Joham, Nadira S. Kakoly, Helena J. Teede, Arul Earnest
Summary: This study found a significantly higher incidence of hypertension among women with PCOS compared to those without, especially among obese women. PCOS was independently associated with an increased risk of hypertension, further exacerbated by obesity. Including PCOS in hypertension risk assessments may help in early identification and management of the disorder.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Obstetrics & Gynecology
Mamaru Ayenew Awoke, Arul Earnest, Anju E. Joham, Allison M. Hodge, Helena J. Teede, Wendy J. Brown, Lisa J. Moran
Summary: This study found that women with PCOS had a significantly higher rate of weight gain compared to women without PCOS, especially those with unhealthy lifestyles. The research highlighted the significant impact of lifestyle on weight gain in women with PCOS.
HUMAN REPRODUCTION
(2022)
Review
Endocrinology & Metabolism
Yujie Shang, Huifang Zhou, Ruohan He, Wentian Lu
Summary: This study found that diet is significantly related to improved fertility outcomes, reproductive endocrine, and clinical hyperandrogenism in women with PCOS. Low-carbohydrate diets were more effective in optimizing reproductive outcomes, while calorie restriction was critical in ameliorating hyperandrogenism. The positive effects were associated with the treatment duration, with longer duration leading to greater improvement.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Public, Environmental & Occupational Health
Stephanie Pirotta, Siew S. Lim, Angela Grassi, Lynn Monahan Couch, Yvonne M. Jeanes, Anju J. Joham, Helena Teede, Lisa J. Moran
Summary: Self-management strategies for physical activity are related to meeting PA recommendations, while nutrition strategies are associated with lower BMI but not diet quality, energy intake, or weight in women with PCOS.
PATIENT EDUCATION AND COUNSELING
(2022)
Article
Endocrinology & Metabolism
Aya Mousa, Kevin Huynh, Stacey J. Ellery, Boyd J. Strauss, Anju E. Joham, Barbora de Courten, Peter J. Meikle, Helena J. Teede
Summary: This study demonstrates that high levels of LPI(18:0) and low levels of DHA-containing lipids are associated with key metabolic risk factors in women with and without polycystic ovary syndrome (PCOS).
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Endocrinology & Metabolism
Claire Falzarano, Taylor Lofton, Adjoa Osei-Ntansah, Trinitee Oliver, Taylor Southward, Salim Stewart, Stanley Andrisse
Summary: Recent research has shown a high prevalence of nonalcoholic fatty liver disease (NAFLD) in women with polycystic ovary syndrome (PCOS). Women with normal weight can also develop NAFLD. The majority of studies focus on adult, premenopausal women and little attention has been given to young and adolescent women with NAFLD. Future research should include more diverse populations and study the contribution of excess androgens and insulin resistance to NAFLD risk in women with PCOS of varying weights, ages, and ethnicities.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Reproductive Biology
Narges Zaeemzadeh, Shahideh Jahanian Sadatmahalleh, Saeideh Ziaei, Anoshirvan Kazemnejad, Maryam Movahedinejad, Azadeh Mottaghi, Neda Mohamadzadeh
Summary: The dietary intake of antioxidant micronutrients was significantly lower in PCOS women with MetS compared to those without MetS, indicating a potential protective effect of these nutrients against MetS.
JOURNAL OF OVARIAN RESEARCH
(2021)
Article
Endocrinology & Metabolism
Iris Lee, Julia Vresilovic, Maryam Irfan, Robert Gallop, Anuja Dokras
Summary: The study found that there is a difference in the risk of metabolic syndrome in women with polycystic ovary syndrome between Black and White women, with Black women having a higher incidence rate. In addition to early cardiometabolic screening at the time of diagnosis, this population also requires ongoing and frequent screening.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Endocrinology & Metabolism
Izabela Chudzicka-Strugala, Anna Kubiak, Beata Banaszewska, Barbara Zwozdziak, Martyna Siakowska, Leszek Pawelczyk, Antoni J. Duleba
Summary: The study demonstrated that in women with PCOS, lifestyle modifications combined with synbiotic supplementation can significantly decrease body weight, waist circumference, hip circumference, and thigh circumference, as well as lead to a significant reduction in serum testosterone levels.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Endocrinology & Metabolism
Izabela Chudzicka-Strugala, Anna Kubiak, Beata Banaszewska, Barbara Zwozdziak, Martyna Siakowska, Leszek Pawelczyk, Antoni J. Duleba
Summary: The study found that synbiotic supplementation can enhance the effects of lifestyle modifications on weight and testosterone levels in patients with PCOS, leading to significant improvements.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Obstetrics & Gynecology
Heidi Vanden Brink, Amy D. Willis, Brittany Y. Jarrett, Annie W. Lin, Steven Soler, Sian Best, Erica L. Bender, Andrew K. Peppin, Kathleen M. Hoeger, Marla E. Lujan
FERTILITY AND STERILITY
(2016)
Article
Obstetrics & Gynecology
Annie W. Lin, Jamie S. Dollahite, Jeffery Sobal, Marla E. Lujan
HUMAN REPRODUCTION
(2018)
Editorial Material
Nutrition & Dietetics
Brittany Y. Jarrett, Annie W. Lin, Marla E. Lujan
JOURNAL OF THE ACADEMY OF NUTRITION AND DIETETICS
(2019)
Article
Medicine, Research & Experimental
Daniel O. Clark, Huiping Xu, Lyndsi Moser, Philip Adeoye, Annie W. Lin, Christy C. Tangney, Shannon L. Risacher, Andrew J. Saykin, Robert Considine, Frederick W. Unverzagt
CONTEMPORARY CLINICAL TRIALS
(2019)
Article
Health Care Sciences & Services
Nabil Alshurafa, Annie Wen Lin, Fengqing Zhu, Roozbeh Ghaffari, Josiah Hester, Edward Delp, John Rogers, Bonnie Spring
JOURNAL OF MEDICAL INTERNET RESEARCH
(2019)
Article
Nutrition & Dietetics
Annie W. Lin, Maryam Kazemi, Brittany Y. Jarrett, Heidi Vanden Brink, Kathleen M. Hoeger, Steven D. Spandorfer, Marla E. Lujan
Article
Nutrition & Dietetics
Maryam Kazemi, Brittany Y. Jarrett, Heidi Vanden Brink, Annie W. Lin, Kathleen M. Hoeger, Steven D. Spandorfer, Marla E. Lujan
Article
Public, Environmental & Occupational Health
Annie W. Lin, David Siscovick, Barbara Sternfeld, Pamela Schreiner, Cora E. Lewis, Erica T. Wang, Sharon S. Merkin, Melissa Wellons, Lyn Steffen, Ronit Calderon-Margalit, Patricia A. Cassano, Marla E. Lujan
Summary: The study found little to no association between diet and physical activity with polycystic ovary syndrome (PCOS) and its symptoms. Therefore, the need for tailored dietary and physical activity recommendations for patients with PCOS is still debated.
Article
Behavioral Sciences
Nabil Alshurafa, Shibo Zhang, Christopher Romano, Hui Zhang, Angela Fidler Pfammatter, Annie W. Lin
Summary: The study found that under free-living conditions, more bites and slower eating speed were significantly associated with higher energy intake. Obesity did not modify these associations. These results highlight how eating behaviors can impact energy balance.
Article
Biotechnology & Applied Microbiology
Annie W. Lin, Frank A. Granata IV, Abigail K. Trippel, Leslie Tello, Tammy K. Stump, Mandy Wong, Mercedes R. Carnethon, Kiarri N. Kershaw, Jennifer Makelarski, Daniel Weller
Summary: This study investigated food handling concerns and practices among Chicago residents during the COVID-19 pandemic, and found that food insecure participants were more concerned about COVID-19 foodborne transmission and engaged in unsafe food handling practices more frequently. The results highlight the need for further understanding of barriers to safe food handling knowledge and practices, particularly among those with food insecurity.
JOURNAL OF FOOD PROTECTION
(2022)
Article
Biochemistry & Molecular Biology
Adam T. Evans, Heidi Vanden Brink, Jessica S. Lim, Brittany Y. Jarrett, Annie W. Lin, Marla E. Lujan, Kathleen Hoeger
Summary: Circulating melatonin is elevated in women with polycystic ovary syndrome (PCOS), and altered patterns of melatonin excretion may be associated with reduced sleep quality in these women. This study found that women with PCOS had lower weekend sleep efficiency compared to controls, and the number of follicles per ovary was positively associated with overnight melatonin levels. These findings suggest that PCOS diagnostic features are related to melatonin production and sleep disturbances.
Article
Health Care Sciences & Services
Nabil I. Alshurafa, Tammy K. Stump, Christopher S. Romano, Angela F. Pfammatter, Annie W. Lin, Josiah Hester, Donald Hedeker, Evan Forman, Bonnie Spring
Summary: This study aims to identify automatically detectable features that predict overeating and build clusters of eating episodes based on social and psychological features. It involves a 14-day observational study with 60 obese adults, using sensors and ecological momentary assessments to collect data. Machine learning methods will be applied to analyze the features and generate clusters. This study is expected to provide new insights into the determinants of overeating.
Article
Public, Environmental & Occupational Health
Annie W. Lin, Sara H. Marchese, Laura E. Finch, Tammy Stump, Kara L. Gavin, Bonnie Spring
Summary: This study explored the associations between cancer beliefs and health behavior engagement in cancer survivors, particularly focusing on those with overweight and obesity. The results showed that engagement in healthier behaviors among survivors with overweight or obesity was related to feeling less overwhelmed by cancer risk recommendations and believing that physical activity or obesity influences cancer development. Additionally, obesity altered the associations between cancer risk beliefs and health behavior engagement in the overall sample.
PATIENT EDUCATION AND COUNSELING
(2021)
Article
Oncology
Annie Wen Lin, Sharon H. Baik, David Aaby, Leslie Tello, Twila Linville, Nabil Alshurafa, Bonnie Spring
Article
Endocrinology & Metabolism
Annie W. Lin, Elena J. Bergomi, Jamie S. Dollahite, Jeffery Sobal, Kathleen M. Hoeger, Marla E. Lujan
JOURNAL OF THE ENDOCRINE SOCIETY
(2018)
Review
Nutrition & Dietetics
Chong-Su Kim
Summary: The gut microbiota plays a crucial role in brain function through the gut-brain axis. This review highlights the effects of gut microbiota-derived dietary metabolites on cell-to-cell interactions in the central nervous system, particularly microglia, astrocytes, and neuronal cells, affecting cognitive function, mood, and behavior. The review also discusses the potential of diet-induced microbial metabolite-based therapies as novel approaches to mental health treatment.
ADVANCES IN NUTRITION
(2024)