Riboflavin and pantothenic acid biosynthesis are crucial for iron homeostasis and virulence in the pathogenic mold Aspergillus fumigatus

The quinoline bromoquinol exhibits broad-spectrum antifungal activity and induces oxidative stress and apoptosis in Aspergillus fumigatus

(2017) Dafna Ben Yaakov et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

The antifungal pipeline: a reality check

(2017) John R. Perfect   NATURE REVIEWS DRUG DISCOVERY

A Nonredundant Phosphopantetheinyl Transferase, PptA, Is a Novel Antifungal Target That Directs Secondary Metabolite, Siderophore, and Lysine Biosynthesis in Aspergillus fumigatus and Is Critical for Pathogenicity

(2017) Anna Johns et al.   mBio

Exploration of Sulfur Assimilation of Aspergillus fumigatus Reveals Biosynthesis of Sulfur-Containing Amino Acids as a Virulence Determinant

(2016) Jorge Amich et al.   INFECTION AND IMMUNITY

Production of cross-kingdom oxylipins by pathogenic fungi: An update on their role in development and pathogenicity

(2016) Gregory J. Fischer et al.   JOURNAL OF MICROBIOLOGY

Histidine biosynthesis plays a crucial role in metal homeostasis and virulence ofAspergillus fumigatus

(2016) Anna-Maria Dietl et al.   Virulence

Optimization of Inhibitors ofMycobacterium tuberculosisPantothenate Synthetase Based on Group Efficiency Analysis

(2015) Alvin W. Hung et al.   ChemMedChem

Essential Gene Discovery in the Basidiomycete Cryptococcus neoformans for Antifungal Drug Target Prioritization

(2015) Giuseppe Ianiri et al.   mBio

Mutant characterization andin vivoconditional repression identify aromatic amino acid biosynthesis to be essential forAspergillus fumigatusvirulence

(2015) Anna Sasse et al.   Virulence

The flavoproteome of the yeast Saccharomyces cerevisiae

(2014) Venugopal Gudipati et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Predicting essential genes for identifying potential drug targets in Aspergillus fumigatus

(2014) Yao Lu et al.   COMPUTATIONAL BIOLOGY AND CHEMISTRY

Fungal siderophore metabolism with a focus on Aspergillus fumigatus

(2014) Hubertus Haas   NATURAL PRODUCT REPORTS

Characterization of the Aspergillus fumigatus detoxification systems for reactive nitrogen intermediates and their impact on virulence

(2014) Katrin Lapp et al.   Frontiers in Microbiology

Histoplasma capsulatum Depends onDe NovoVitamin Biosynthesis for Intraphagosomal Proliferation

(2013) Andrew L. Garfoot et al.   INFECTION AND IMMUNITY

TheAspergillusGenome Database: multispecies curation and incorporation of RNA-Seq data to improve structural gene annotations

(2013) Gustavo C. Cerqueira et al.   NUCLEIC ACIDS RESEARCH

Hypoxia and Fungal Pathogenesis: To Air or Not To Air?

(2012) Nora Grahl et al.   EUKARYOTIC CELL

Tackling Human Fungal Infections

(2012) G. D. Brown et al.   SCIENCE

Iron – A Key Nexus in the Virulence of Aspergillus fumigatus

(2012) Hubertus Haas   Frontiers in Microbiology

Validation of a Self-Excising Marker in the Human Pathogen Aspergillus fumigatus by Employing the  -Rec/six Site-Specific Recombination System

(2010) T. Hartmann et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Riboflavin Biosynthetic and Regulatory Factors as Potential Novel Anti-Infective Drug Targets

(2010) Quanxin Long et al.   Chemical Biology & Drug Design

The choC gene encoding a putative phospholipid methyltransferase is essential for growth and development in Aspergillus nidulans

(2010) Li Tao et al.   CURRENT GENETICS

Evaluation of Lysine Biosynthesis as an Antifungal Drug Target: Biochemical Characterization of Aspergillus fumigatus Homocitrate Synthase and Virulence Studies

(2010) Felicitas Schöbel et al.   EUKARYOTIC CELL

Vitamin B6 biosynthesis is essential for survival and virulence of Mycobacterium tuberculosis

(2010) Thomas Dick et al.   MOLECULAR MICROBIOLOGY

Transcriptome analysis of nitrate assimilation in Aspergillus nidulans reveals connections to nitric oxide metabolism

(2010) Thorsten Schinko et al.   MOLECULAR MICROBIOLOGY

Pathway analysis of Candida albicans survival and virulence determinants in a murine infection model

(2010) J. M. Becker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HapX-Mediated Adaption to Iron Starvation Is Crucial for Virulence of Aspergillus fumigatus

(2010) Markus Schrettl et al.   PLoS Pathogens

Impaired Intestinal Vitamin B1 (Thiamin) Uptake in Thiamin Transporter-2–Deficient Mice

(2009) Jack C. Reidling et al.   GASTROENTEROLOGY

Discovery and Development of the Covalent Hydrates of Trifluoromethylated Pyrazoles as Riboflavin Synthase Inhibitors with Antibiotic Activity AgainstMycobacterium tuberculosis

(2009) Yujie Zhao et al.   JOURNAL OF ORGANIC CHEMISTRY

Essential pathway identification: fromin silicoanalysis to potential antifungal targets inAspergillus fumigatus

(2009) Jette Thykaer et al.   MEDICAL MYCOLOGY