Hypoxia promotes breast cancer cell invasion through HIF-1α-mediated up-regulation of the invadopodial actin bundling protein CSRP2

Integration of hypoxic HIF-α signaling in blood cancers

(2017) L Schito et al.   ONCOGENE

Tumor Cell Invadopodia: Invasive Protrusions that Orchestrate Metastasis

(2017) Robert J. Eddy et al.   TRENDS IN CELL BIOLOGY

Cysteine and glycine-rich protein 2 (CSRP2) transcript levels correlate with leukemia relapse and leukemia-free survival in adults with B-cell acute lymphoblastic leukemia and normal cytogenetics

(2017) Shu-Juan Wang et al.   Oncotarget

The hypoxic tumor microenvironment: A driving force for breast cancer progression

(2016) Gregg L. Semenza   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer

(2016) Aifu Lin et al.   NATURE CELL BIOLOGY

Hypoxic control of metastasis

(2016) E. B. Rankin et al.   SCIENCE

CRP2, a new invadopodia actin bundling factor critically promotes breast cancer cell invasion and metastasis

(2016) Céline Hoffmann et al.   Oncotarget

H19 Noncoding RNA, an Independent Prognostic Factor, Regulates Essential Rb-E2F and CDK8-β-Catenin Signaling in Colorectal Cancer

(2016) Masahisa Ohtsuka et al.   EBioMedicine

Invadopodia: a new therapeutic target to block cancer metastasis

(2015) Konstantin Stoletov et al.   Expert Review of Anticancer Therapy

Hypoxia-inducible factor 1 and breast cancer metastasis

(2015) Zhao-ji Liu et al.   Journal of Zhejiang University-SCIENCE B

The Invadopodia Scaffold Protein Tks5 Is Required for the Growth of Human Breast Cancer Cells In Vitro and In Vivo

(2015) Barbara Blouw et al.   PLoS One

Hypoxia-Inducible Factor-1 Promotes Pancreatic Ductal Adenocarcinoma Invasion and Metastasis by Activating Transcription of the Actin-Bundling Protein Fascin

(2014) X. Zhao et al.   CANCER RESEARCH

Stratifying fascin and cortactin function in invadopodium formation using inhibitory nanobodies and targeted subcellular delocalization

(2014) Isabel Van Audenhove et al.   FASEB JOURNAL

Human Muscle LIM Protein Dimerizes along the Actin Cytoskeleton and Cross-Links Actin Filaments

(2014) Céline Hoffmann et al.   MOLECULAR AND CELLULAR BIOLOGY

Extravasation during bladder cancer metastasis requires cortactin-mediated invadopodia formation

(2014) NORIKO TOKUI et al.   Molecular Medicine Reports

Regulation of invadopodia by the tumor microenvironment

(2014) Christine M Gould et al.   Cell Adhesion & Migration

Invadopodia Are Required for Cancer Cell Extravasation and Are a Therapeutic Target for Metastasis

(2014) Hon S. Leong et al.   Cell Reports

Multiparametric Classification Links Tumor Microenvironments with Tumor Cell Phenotype

(2014) Bojana Gligorijevic et al.   PLOS BIOLOGY

Tks5 and SHIP2 Regulate Invadopodium Maturation, but Not Initiation, in Breast Carcinoma Cells

(2013) Ved P. Sharma et al.   CURRENT BIOLOGY

Role of hypoxia-inducible factors in breast cancer metastasis

(2013) Daniele M Gilkes et al.   Future Oncology

Notch increases the shedding of HB-EGF by ADAM12 to potentiate invadopodia formation in hypoxia

(2013) Begoña Díaz et al.   JOURNAL OF CELL BIOLOGY

HIF1α and HIF2α independently activate SRC to promote melanoma metastases

(2013) Sara C. Hanna et al.   JOURNAL OF CLINICAL INVESTIGATION

HDAC6 Deacetylase Activity Is Required for Hypoxia-Induced Invadopodia Formation and Cell Invasion

(2013) Dominique Arsenault et al.   PLoS One

N-WASP-mediated invadopodium formation is involved in intravasation and lung metastasis of mammary tumors

(2012) B. Gligorijevic et al.   JOURNAL OF CELL SCIENCE

Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy

(2012) Gregg L. Semenza   TRENDS IN PHARMACOLOGICAL SCIENCES

Degrading Devices: Invadosomes in Proteolytic Cell Invasion

(2011) Stefan Linder et al.   Annual Review of Cell and Developmental Biology

Hypoxia-Induced Invadopodia Formation Involves Activation of NHE-1 by the p90 Ribosomal S6 Kinase (p90RSK)

(2011) Fabrice Lucien et al.   PLoS One

The Actin-Bundling Protein Fascin Stabilizes Actin in Invadopodia and Potentiates Protrusive Invasion

(2010) Ang Li et al.   CURRENT BIOLOGY

Actin, microtubules, and vimentin intermediate filaments cooperate for elongation of invadopodia

(2010) Marie Schoumacher et al.   JOURNAL OF CELL BIOLOGY

An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients

(2009) Balazs Györffy et al.   BREAST CANCER RESEARCH AND TREATMENT

Actin machinery and mechanosensitivity in invadopodia, podosomes and focal adhesions

(2009) C. Albiges-Rizo et al.   JOURNAL OF CELL SCIENCE

Activation of Matrix Metalloproteinase-2 (MMP-2) by Membrane Type 1 Matrix Metalloproteinase through an Artificial Receptor for ProMMP-2 Generates Active MMP-2

(2008) Yuki Nishida et al.   CANCER RESEARCH