Regulation of invadopodia by the tumor microenvironment

Membrane lipids in invadopodia and podosomes: Key structures for cancer invasion and metastasis

(2015)   Oncotarget

Regulation of the Na+/H+ Exchanger (NHE1) in Breast Cancer Metastasis

(2013) S. R. Amith et al.   CANCER RESEARCH

Tks5 and SHIP2 Regulate Invadopodium Maturation, but Not Initiation, in Breast Carcinoma Cells

(2013) Ved P. Sharma et al.   CURRENT BIOLOGY

Cancer cell metabolism regulates extracellular matrix degradation by invadopodia

(2013) Remco van Horssen et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Differential Tks5 isoform expression contributes to metastatic invasion of lung adenocarcinoma

(2013) C. M.-C. Li et al.   GENES & DEVELOPMENT

CD147, CD44, and the Epidermal Growth Factor Receptor (EGFR) Signaling Pathway Cooperate to Regulate Breast Epithelial Cell Invasiveness

(2013) G. Daniel Grass et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Notch increases the shedding of HB-EGF by ADAM12 to potentiate invadopodia formation in hypoxia

(2013) Begoña Díaz et al.   JOURNAL OF CELL BIOLOGY

Signaling inputs to invadopodia and podosomes

(2013) D. Hoshino et al.   JOURNAL OF CELL SCIENCE

HIF1α and HIF2α independently activate SRC to promote melanoma metastases

(2013) Sara C. Hanna et al.   JOURNAL OF CLINICAL INVESTIGATION

β1 integrin regulates Arg to promote invadopodial maturation and matrix degradation

(2013) Brian T. Beaty et al.   MOLECULAR BIOLOGY OF THE CELL

Advances in targeting cell surface signalling molecules for immune modulation

(2013) Sheng Yao et al.   NATURE REVIEWS DRUG DISCOVERY

Palladin promotes invasion of pancreatic cancer cells by enhancing invadopodia formation in cancer-associated fibroblasts

(2013) S M Goicoechea et al.   ONCOGENE

Autocrine HBEGF expression promotes breast cancer intravasation, metastasis and macrophage-independent invasion in vivo

(2013) Z N Zhou et al.   ONCOGENE

Macrophage contact induces RhoA GTPase signaling to trigger tumor cell intravasation

(2013) M Roh-Johnson et al.   ONCOGENE

HDAC6 Deacetylase Activity Is Required for Hypoxia-Induced Invadopodia Formation and Cell Invasion

(2013) Dominique Arsenault et al.   PLoS One

Na+-H+ Exchanger, pH Regulation and Cancer

(2013) Stephan J. Reshkin et al.   Recent Patents on Anti-Cancer Drug Discovery

Arousal of cancer-associated stromal fibroblasts

(2013) Teresa A. Brentnall   Cell Adhesion & Migration

Hypoxia-induced invadopodia formation: a role for  -PIX

(2013) N. F. Md Hashim et al.   Open Biology

Pericyte Depletion Results in Hypoxia-Associated Epithelial-to-Mesenchymal Transition and Metastasis Mediated by Met Signaling Pathway

(2012) Vesselina G. Cooke et al.   CANCER CELL

Trespassing cancer cells: ‘fingerprinting’ invasive protrusions reveals metastatic culprits

(2012) Richard L Klemke   CURRENT OPINION IN CELL BIOLOGY

Pathological roles of invadopodia in cancer invasion and metastasis

(2012) Hideki Yamaguchi   EUROPEAN JOURNAL OF CELL BIOLOGY

pH regulators in invadosomal functioning: Proton delivery for matrix tasting

(2012) Lucie Brisson et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

ATAT1/MEC-17 acetyltransferase and HDAC6 deacetylase control a balance of acetylation of alpha-tubulin and cortactin and regulate MT1-MMP trafficking and breast tumor cell invasion

(2012) Antonio Castro-Castro et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Tks5-dependent formation of circumferential podosomes/invadopodia mediates cell–cell fusion

(2012) Tsukasa Oikawa et al.   JOURNAL OF CELL BIOLOGY

N-WASP-mediated invadopodium formation is involved in intravasation and lung metastasis of mammary tumors

(2012) B. Gligorijevic et al.   JOURNAL OF CELL SCIENCE

Ableson kinases negatively regulate invadopodia function and invasion in head and neck squamous cell carcinoma by inhibiting an HB-EGF autocrine loop

(2012) K E Hayes et al.   ONCOGENE

Arousal of Cancer-Associated Stroma: Overexpression of Palladin Activates Fibroblasts to Promote Tumor Invasion

(2012) Teresa A. Brentnall et al.   PLoS One

Metabolic Regulation of Invadopodia and Invasion by Acetyl-CoA Carboxylase 1 and De novo Lipogenesis

(2012) Kristen E. N. Scott et al.   PLoS One

Hypoxia promotes ligand-independent EGF receptor signaling via hypoxia-inducible factor-mediated upregulation of caveolin-1

(2012) Y. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Network Analysis of the Focal Adhesion to Invadopodia Transition Identifies a PI3K-PKC  Invasive Signaling Axis

(2012) D. Hoshino et al.   Science Signaling

Degrading Devices: Invadosomes in Proteolytic Cell Invasion

(2011) Stefan Linder et al.   Annual Review of Cell and Developmental Biology

Formation of invadopodia-like structures by synovial cells promotes cartilage breakdown in collagen-induced arthritis: Involvement of the protein tyrosine kinase Src

(2011) Annie Lauzier et al.   ARTHRITIS AND RHEUMATISM

Twist1-Induced Invadopodia Formation Promotes Tumor Metastasis

(2011) Mark A. Eckert et al.   CANCER CELL

Pten in the Breast Tumor Microenvironment: Modeling Tumor–Stroma Coevolution: Figure 1.

(2011) Julie A. Wallace et al.   CANCER RESEARCH

An EGFR-Src-Arg-Cortactin Pathway Mediates Functional Maturation of Invadopodia and Breast Cancer Cell Invasion

(2011) C. C. Mader et al.   CANCER RESEARCH

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

A Novel Spatiotemporal RhoC Activation Pathway Locally Regulates Cofilin Activity at Invadopodia

(2011) Jose Javier Bravo-Cordero et al.   CURRENT BIOLOGY

Invadosome regulation by adhesion signaling

(2011) Olivier Destaing et al.   CURRENT OPINION IN CELL BIOLOGY

Class IIb HDAC6 regulates endothelial cell migration and angiogenesis by deacetylation of cortactin

(2011) David Kaluza et al.   EMBO JOURNAL

NHE1 mediates MDA-MB-231 cells invasion through the regulation of MT1-MMP

(2011) Yani Lin et al.   EXPERIMENTAL CELL RESEARCH

Podosomal proteins as causes of human syndromes: A role in craniofacial development?

(2011) Pilar Cejudo-Martin et al.   GENESIS

Cortactin phosphorylation regulates cell invasion through a pH-dependent pathway

(2011) Marco A. O. Magalhaes et al.   JOURNAL OF CELL BIOLOGY

Phosphoinositide 3-kinase signaling pathway mediated by p110α regulates invadopodia formation

(2011) Hideki Yamaguchi et al.   JOURNAL OF CELL BIOLOGY

Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases

(2011) Peter Carmeliet et al.   NATURE REVIEWS DRUG DISCOVERY

The 'ins' and 'outs' of podosomes and invadopodia: characteristics, formation and function

(2011) Danielle A. Murphy et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Hypoxia-Induced Invadopodia Formation Involves Activation of NHE-1 by the p90 Ribosomal S6 Kinase (p90RSK)

(2011) Fabrice Lucien et al.   PLoS One

A Cell-Based High-Content Screening Assay Reveals Activators and Inhibitors of Cancer Cell Invasion

(2011) M. Quintavalle et al.   Science Signaling

The tumor microenvironment

(2011) Cynthia E. Weber et al.   SURGICAL ONCOLOGY-OXFORD

Matrix Metalloproteinases: Regulators of the Tumor Microenvironment

(2010) Kai Kessenbrock et al.   CELL

Macrophage Diversity Enhances Tumor Progression and Metastasis

(2010) Bin-Zhi Qian et al.   CELL

Hypoxia and Hypoxia-Inducible Factors: Master Regulators of Metastasis

(2010) X. Lu et al.   CLINICAL CANCER RESEARCH

Analysis of the signaling pathways regulating Src-dependent remodeling of the actin cytoskeleton

(2010) Sabina E. Winograd-Katz et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Novel invadopodia components revealed by differential proteomic analysis

(2010) Francesca Attanasio et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Dynamic membrane remodeling at invadopodia differentiates invadopodia from podosomes

(2010) Vira V. Artym et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

HDAC6 is required for invadopodia activity and invasion by breast tumor cells

(2010) Mercedes Rey et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Extracellular engagement of ADAM12 induces clusters of invadopodia with localized ectodomain shedding activity

(2010) Reidar Albrechtsen et al.   EXPERIMENTAL CELL RESEARCH

NHE1 promotes invadopodial ECM proteolysis through acidification of the peri-invadopodial space

(2010) Giovanni Busco et al.   FASEB JOURNAL

High-throughput live-cell imaging reveals differential inhibition of tumor cell proliferation by human fibroblasts

(2010) Emilie Flaberg et al.   INTERNATIONAL JOURNAL OF CANCER

PtdIns(3,4)P2 instigates focal adhesions to generate podosomes

(2010) Tsukasa Oikawa et al.   Cell Adhesion & Migration

Lipid Rafts and Caveolin-1 Are Required for Invadopodia Formation and Extracellular Matrix Degradation by Human Breast Cancer Cells

(2009) H. Yamaguchi et al.   CANCER RESEARCH

Growth factors in tumor microenvironment

(2009) Xuejing Zhang   Frontiers in Bioscience-Landmark

Cortactin regulates cofilin and N-WASp activities to control the stages of invadopodium assembly and maturation

(2009) Matthew Oser et al.   JOURNAL OF CELL BIOLOGY

Protease-dependent versus -independent cancer cell invasion programs: three-dimensional amoeboid movement revisited

(2009) Farideh Sabeh et al.   JOURNAL OF CELL BIOLOGY

Matrix invasion by tumour cells: a focus on MT1-MMP trafficking to invadopodia

(2009) R. Poincloux et al.   JOURNAL OF CELL SCIENCE

Actin machinery and mechanosensitivity in invadopodia, podosomes and focal adhesions

(2009) C. Albiges-Rizo et al.   JOURNAL OF CELL SCIENCE

HIF-1α Modulates Energy Metabolism in Cancer Cells by Inducing Over-Expression of Specific Glycolytic Isoforms

(2009) Alvaro Marin-Hernandez et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

The Novel Adaptor Protein Tks4 (SH3PXD2B) Is Required for Functional Podosome Formation

(2009) Matthew D. Buschman et al.   MOLECULAR BIOLOGY OF THE CELL

Pten in stromal fibroblasts suppresses mammary epithelial tumours

(2009) Anthony J. Trimboli et al.   NATURE

Tks5-Dependent, Nox-Mediated Generation of Reactive Oxygen Species Is Necessary for Invadopodia Formation

(2009) B. Diaz et al.   Science Signaling

Na+/H+Exchangers and RhoA Regulate Acidic Extracellular pH-Induced Lysosome Trafficking in Prostate Cancer Cells

(2009) Joshua J. Steffan et al.   TRAFFIC

Aiming for invadopodia: organizing polarized delivery at sites of invasion

(2009) Giusi Caldieri et al.   TRENDS IN CELL BIOLOGY

Assembly and biological role of podosomes and invadopodia

(2008) Mario Gimona et al.   CURRENT OPINION IN CELL BIOLOGY

Microenvironmental regulation of cancer development

(2008) Min Hu et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

A role for the podosome/invadopodia scaffold protein Tks5 in tumor growth in vivo

(2008) B BLOUW et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Sequential signals toward podosome formation in NIH-src cells

(2008) Tsukasa Oikawa et al.   JOURNAL OF CELL BIOLOGY

Cofilin is a pH sensor for actin free barbed end formation: role of phosphoinositide binding

(2008) Christian Frantz et al.   JOURNAL OF CELL BIOLOGY

Direct regulation of TWIST by HIF-1α promotes metastasis

(2008) Muh-Hwa Yang et al.   NATURE CELL BIOLOGY

Aggressiveness of HNSCC tumors depends on expression levels of cortactin, a gene in the 11q13 amplicon

(2008) E S Clark et al.   ONCOGENE

Co-evolution of tumor cells and their microenvironment

(2008) Kornelia Polyak et al.   TRENDS IN GENETICS